Zobrazeno 1 - 10
of 20
pro vyhledávání: '"George Griesgraber"'
Publikováno v:
Antimicrobial Agents and Chemotherapy. 46:1357-1363
In vitro studies have demonstrated that water-soluble, nontoxic phosphoramidates of azidothymidine (zidovudine [AZT]) have significant and specific anti-human immunodeficiency virus and anticancer activity. Although polar, these compounds are interna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6ecfaa4984cc205455a81a9d242d997
https://doi.org/10.1128/aac.46.5.1357-1363.2002
https://doi.org/10.1128/aac.46.5.1357-1363.2002
Publikováno v:
Journal of Medicinal Chemistry. 44:223-231
A series of phosphoramidate monoesters of 3'-azido-3'-deoxythymidine (AZT) bearing aliphatic amino acid methyl esters (3a, 3c, 4a, 4c, 5-7) and methyl amides (3b, 3d, 4b, 4d) was prepared and evaluated for anti-HIV-1 activity in peripheral blood mono
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb9bfd27057940718e94f63a136961cd
https://doi.org/10.1021/jm000260r
https://doi.org/10.1021/jm000260r
Autor:
Yat Sun Or, Angela M. Nilius, Rodger F. Henry, Pauline M. Johnson, George Griesgraber, Daniel T. W. Chu, Jacob J. Plattner, Robert K. Flamm
Publikováno v:
The Journal of Antibiotics. 49:465-477
The 11,12-cyclic carbazate of 3-keto-6-O-methylerythromycin A (4) was prepared. This compound shows in vitro antibacterial activity comparable to erythromycin A (1) against erythromycin-susceptible organisms and increased activity against some erythr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56d0227d3f059102bcd211a9e8c2d8a1
https://doi.org/10.7164/antibiotics.49.465
https://doi.org/10.7164/antibiotics.49.465
Publikováno v:
Journal of the American Chemical Society. 117:197-210
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0829ac53cebe94a2b11ad1567978cab4
https://doi.org/10.1021/ja00106a024
https://doi.org/10.1021/ja00106a024
Publikováno v:
ChemInform. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::059d2d78b5f252878bb5fcca1dfb8b23
https://doi.org/10.1002/chin.199204052
https://doi.org/10.1002/chin.199204052
Publikováno v:
ChemInform. 23
We have developed a new iterative and convergent synthesis of alternating (1,3,5...) polyol chains based on enantiomerically enriched (94% ee) chloro nitrile 1. Chloro nitrile 1 is both a potential nucleophile and a potential electrophile; orthogonal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff98906d7a3db8a2acea7bf71ebbcbf5
https://doi.org/10.1002/chin.199233137
https://doi.org/10.1002/chin.199233137
Publikováno v:
ChemInform. 24
Milbemycin spiroacetal 4 was prepared from (4S,5R)-4,5-dimethylpentan-5-olide 5 and (R)-1-(benzyloxymethyl)oxirane by alkylation and stereoselective reductive decyanation of the intermediate spiroacetal cyanohydrin 7.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15a784b6dfbaa7d6eba3f1edb5cea7a3
https://doi.org/10.1002/chin.199324175
https://doi.org/10.1002/chin.199324175
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a002df24297dd57e7ed3da33fb97575
https://doi.org/10.1002/chin.199430247
https://doi.org/10.1002/chin.199430247
Autor:
George Griesgraber, Yat Sun Or, Jacob J. Plattner, Daniel T. W. Chu, Robert K. Flamm, Rodger F. Henry, Pauline M. Johnson, Angela M. Nilius
Publikováno v:
ChemInform. 27
The 11,12-cyclic carbazate of 3-keto-6-O-methylerythromycin A (4) was prepared. This compound shows in vitro antibacterial activity comparable to erythromycin A (1) against erythromycin-susceptible organisms and increased activity against some erythr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::179c1d36929578598206c6aee19496ce
https://doi.org/10.1002/chin.199643237
https://doi.org/10.1002/chin.199643237
Publikováno v:
The Journal of Organic Chemistry. 57:1559-1563
We have developed a new iterative and convergent synthesis of alternating (1,3,5...) polyol chains based on enantiomerically enriched (94% ee) chloro nitrile 1. Chloro nitrile 1 is both a potential nucleophile and a potential electrophile; orthogonal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff85f1837b5ed0cc1385164826cd9d89
https://doi.org/10.1021/jo00031a041
https://doi.org/10.1021/jo00031a041