Zobrazeno 1 - 10
of 14
pro vyhledávání: '"George G. Bierkamper"'
Autor:
George G. Bierkamper, Kris Alan Smith
Publikováno v:
European Journal of Pharmacology. 176:45-55
Neonatal Long-Evans hooded rats were treated with AY-9944, a cholesterol biosynthesis inhibitor, every 6 days for 7 weeks to induce a permanent absence-like epileptic condition. AY-9944-treated rats averaged 50 +/- 15 generalized non-motor seizures p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51cfef074bda346bd2ad6799ebe82936
https://doi.org/10.1016/0014-2999(90)90130-x
https://doi.org/10.1016/0014-2999(90)90130-x
Publikováno v:
Brain Research. 186:474-479
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a5138f9a3d26c1e35ab736bf1d85313
https://doi.org/10.1016/0006-8993(80)90994-4
https://doi.org/10.1016/0006-8993(80)90994-4
Publikováno v:
Epilepsia. 19:155-167
UMMARY The present study was designed to elucidate cerebral cortical cholesterol changes observed earlier in cobalt-induced epilepsy in the rat. This model is produced by insertion of cobalt metal rods into the cerebral cortex. Seven days after impla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::211cf3689ea9f12b3ae8c7ee27ebf085
https://doi.org/10.1111/j.1528-1157.1978.tb05026.x
https://doi.org/10.1111/j.1528-1157.1978.tb05026.x
Autor:
George G. Bierkamper
Publikováno v:
European Journal of Pharmacology. 73:343-348
The effects of the anticholinesterase agent, diisopropyfluorophosphate (DFP) on neuromuscular transmission were explored using intracellular recording techniques in a vascular perfused rat phrenic nerve-hemidiaphragm preparation. This study was desig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a35b96094662b34bdc8b9ef4a6b80f4
https://doi.org/10.1016/0014-2999(81)90235-1
https://doi.org/10.1016/0014-2999(81)90235-1
Publikováno v:
Brain Research. 150:343-351
Earlier work in our and other laboratories suggest that alteration of brain lipids, primarily sterols, could be a precondition for the development of epileptiform activity. The present study further tests this hypothesis by attempting to produce chro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::521fc09127ac9e143c9d2c66bc654ea9
https://doi.org/10.1016/0006-8993(78)90285-8
https://doi.org/10.1016/0006-8993(78)90285-8
Autor:
George G. Bierkamper, Alan M. Goldberg
Publikováno v:
Brain Research. 202:234-237
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b419432f6c5a47236a2c531eb5cb5454
https://doi.org/10.1016/s0006-8993(80)80052-7
https://doi.org/10.1016/s0006-8993(80)80052-7
Publikováno v:
Epilepsia. 23:243-255
U18666A, an inhibitor of desmosterol reductase (a terminal enzyme in cholesterol synthesis), has been found to produce chronic epileptiform activity in laboratory animals. Since desmosterol might substitute for cholesterol in neuronal membranes witho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b751949256285a83bafd2b2345df045c
https://doi.org/10.1111/j.1528-1157.1982.tb06189.x
https://doi.org/10.1111/j.1528-1157.1982.tb06189.x
Publikováno v:
Life sciences. 43(1)
Following severe thermal injury, patients are resistant to non-depolarizing muscle relaxants. Although this resistance has been well documented clinically, little is known about its etiology. We have tested the hypothesis that circulating factors con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::627d7a257995e5108e0abb7aad335be7
https://pubmed.ncbi.nlm.nih.gov/2968490
https://pubmed.ncbi.nlm.nih.gov/2968490
Publikováno v:
European journal of pharmacology. 115(1)
Acethylcholine (ACh) synthesis by motor nerve terminals requires an adequate supply of its precursor, choline. The results reported here show that diisopropylfluorophosphate (DFP), an acetylcholinesterase inhibitor commonly used in ACh release studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3153f024bb3a2309141d7f31860fcc3d
https://pubmed.ncbi.nlm.nih.gov/4043234
https://pubmed.ncbi.nlm.nih.gov/4043234
Autor:
William R. Millington, Michael J. Kuhar, Marco A. Zarbin, George G. Bierkamper, Elias Aizenman
Publikováno v:
Brain research. 340(2)
[125I]alpha-Bungarotoxin (alpha-BuTX) binding sites accumulate both proximal and distal to a ligature positioned around the sciatic nerve of rats. [125I]alpha-BuTX binding sites, localized using quantitative receptor autoradiography, were found to ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f4032f198661ff58980d4f0762e571
https://pubmed.ncbi.nlm.nih.gov/4027653
https://pubmed.ncbi.nlm.nih.gov/4027653