Zobrazeno 1 - 10
of 329
pro vyhledávání: '"George G, Chen"'
Autor:
Chen Tan, Lingwa Wang, Yifan Yang, Shizhi He, George G. Chen, Jason YK. Chan, Michael CF. Tong, C.A. van Hasselt, Wenbin Xu, Ling Feng, Ru Wang, Jugao Fang
Publikováno v:
Genes and Diseases, Vol 11, Iss 3, Pp 101022- (2024)
Externí odkaz:
https://doaj.org/article/d42408c51eac4629af4d8ccde9f5c55c
Autor:
Peter S. Y. Yu, Kin Wai Chan, Rainbow W. H. Lau, Innes Y. P. Wan, George G. Chen, Calvin S. H. Ng
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
Abstract Multiportal video-assisted thoracic surgery (VATS) for major lung resection causes less immunochemokine production compared to thoracotomy. Whether uniportal VATS is similarly associated with lower early postoperative circulating levels of i
Externí odkaz:
https://doaj.org/article/7330289d71f84833be0351e0dd0aec20
Autor:
Zhongqin Gong, Shucai Yang, Minghui Wei, Alexander C. Vlantis, Jason Y. K. Chan, C. Andrew van Hasselt, Dongcai Li, Xianhai Zeng, Lingbin Xue, Michael C. F. Tong, George G. Chen
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The incidence of thyroid cancer was predominant in women, indicating that the sex hormone may have a role in thyroid cancer development. Generally, the sex hormone exerts its function by binding to the correspondent nuclear receptors. Therefore, aber
Externí odkaz:
https://doaj.org/article/5bdcecf656f142669a720827f210e1d1
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-17 (2020)
Abstract Background Translationally controlled tumor protein (TCTP) is linked to lung cancer. However, upon lung cancer carcinogens stimulation, there were no reports on the relationship between TCTP and lung cell carcinogenic epithelial–mesenchyma
Externí odkaz:
https://doaj.org/article/0d8144078cf4465cb08fd483ac79088c
Autor:
Shucai Yang, Zhongqin Gong, Zhimin Liu, Minghui Wei, Lingbin Xue, Alexander C. Vlantis, Yang Zhang, Jason YK. Chan, C Andrew van Hasselt, Xianhai Zeng, Shuqi Qiu, Nelson Tang, Jing Du, Wei Wei, Michael CF Tong, George G. Chen
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
PurposeThe inhibition of estrogen receptor alpha (ERα) or the activation of ERβ can inhibit papillary thyroid cancer (PTC), but the precise mechanism is not known. We aimed to explore the role of ERα and ERβ on the production of endogenous peroxi
Externí odkaz:
https://doaj.org/article/ecae1b796bb14602b96cc0f5636698c4
Autor:
Ming-Yue Li, Li-Zhong Liu, Wende Li, Calvin S. H. Ng, Yi Liu, Angel W. Y. Kong, Zhili Zhao, Shanshan Wang, Haolong Qi, Hao Jia, Shucai Yang, Jing Du, Xiang Long, Rocky L. K. Ho, Ernest C. W. Chak, Innes Y. P. Wan, Tony S. K. Mok, Malcolm J. Underwood, Nirmal Kumar Gali, Zhi Ning, George G. Chen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-14 (2019)
Abstract Background Epidemiological observations have demonstrated that ambient fine particulate matter with d p
Externí odkaz:
https://doaj.org/article/a362d6757316468cab6f77995e283c81
Autor:
Chenzi Zhang, Xiangjun He, Yvonne K. Kwok, Feng Wang, Junyi Xue, Hui Zhao, Kin Wah Suen, Chi Chiu Wang, Jianwei Ren, George G. Chen, Paul B. S. Lai, Jiangchao Li, Yin Xia, Andrew M. Chan, Wai-Yee Chan, Bo Feng
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-17 (2018)
Abstract Background Cultured human cells are pivotal models to study human gene functions, but introducing complete loss of function in diploid or aneuploid cells has been a challenge. The recently developed CRISPR/Cas9-mediated homology-independent
Externí odkaz:
https://doaj.org/article/babef728911e4c0d8644a39e604dde1c
Publikováno v:
Translational Oncology, Vol 11, Iss 2, Pp 559-566 (2018)
OBJECTIVE: To investigate the correlation between the expression of PD-L1 and HIF-1α in hepatocellular carcinoma (HCC) tissue and further analyze the association with clinical parameters and the prognostic value of coexpression in HCC patients. METH
Externí odkaz:
https://doaj.org/article/2c770cc70da34ff2ac3973d65056dd29
Autor:
Xiaomeng Dai, Jun Xue, Jianli Hu, Sheng-li Yang, George G. Chen, Paul B.S. Lai, Chao Yu, Cui Zeng, Xiefan Fang, Xiaoli Pan, Tao Zhang
Publikováno v:
Translational Oncology, Vol 10, Iss 4, Pp 511-517 (2017)
BACKGROUND: Recurrence or metastasis of hepatocellular carcinoma (HCC) is mainly intrahepatic after curative resection, demonstrating that the peritumoral environment is important but often neglected. Programmed death ligand 1 (PD-L1) in intratumoral
Externí odkaz:
https://doaj.org/article/fcece2c240e042fabb998fa05c876704
Autor:
Shucai Yang, Yi Liu, Ming-Yue Li, Calvin S. H. Ng, Sheng-li Yang, Shanshan Wang, Chang Zou, Yujuan Dong, Jing Du, Xiang Long, Li-Zhong Liu, Innes Y. P. Wan, Tony Mok, Malcolm J. Underwood, George G. Chen
Publikováno v:
Molecular Cancer, Vol 16, Iss 1, Pp 1-12 (2017)
Abstract Background The role of cancer cell FOXP3 in tumorigenesis is conflicting. We aimed to study FOXP3 expression and regulation, function and clinical implication in human non-small cell lung cancer (NSCLC). Methods One hundred and six patients
Externí odkaz:
https://doaj.org/article/51415db869b94c3884e9cb358c38e2c3