Zobrazeno 1 - 6
of 6
pro vyhledávání: '"George Essien Umanah"'
Autor:
Mohammand Aasif Dar, Yongchun Wang, Zhaohao Liao, Andrey Turchinovich, George Essien Umanah, Gaspare La Rocca, Christopher B. Umbricht, Kenneth W. Witwer, Bonita H. Powell, Martha A. Zeiger
Thyroid cancer is the most prevalent endocrine malignancy. We and others have shown that several microRNAs, which are post-transcriptional gene regulators, are aberrantly expressed in anaplastic thyroid cancer (ATC) and papillary thyroid cancer (PTC)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a915db6e7aa733e32f915893e216c37
https://doi.org/10.1101/2020.03.24.006072
https://doi.org/10.1101/2020.03.24.006072
Autor:
Fabienne C. Fiesel, Daniel A. Stevens, Stewart Neifert, Ted M. Dawson, Kathleen Allen, Hojin Kang, Sung Ung Kang, Joo Ho Shin, Leslie A. Scarffe, Yun Il Lee, Haisong Jiang, George Essien Umanah, Wolfdieter Springer, Saurav Brahmachari, Valina L. Dawson, Seung Pil Yun, Tae In Kam, Yunjong Lee, Sangwoo Ham, Jungwoo Wren Kim, Han Seok Ko
Publikováno v:
Cell Reports, Vol 18, Iss 4, Pp 918-932 (2017)
Mutations in PTEN-induced putative kinase 1 (PINK1) and parkin cause autosomal-recessive Parkinson’s disease through a common pathway involving mitochondrial quality control. Parkin inactivation leads to accumulation of the parkin interacting subst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6e7052624dbf2b06109d126d8b9bac
https://doi.org/10.1016/j.celrep.2016.12.090
https://doi.org/10.1016/j.celrep.2016.12.090
Autor:
Hyejin Park, Rong Chen, Nikhil Panicker, Han Seok Ko, Valina L. Dawson, Shaida A. Andrabi, Xiaobo Mao, Tae In Kam, Ted M. Dawson, Alexander Pantelyat, Shih Ching Chou, Senthilkumar S. Karuppagounder, Liana S. Rosenthal, Saurav Brahmachari, Guy G. Poirier, Juan C. Troncoso, George Essien Umanah, Lynn M. Bekris, Chen Qi, Seung Pil Yun, James B. Leverenz, Olga Pletnikova
Publikováno v:
Science. 362
PAR promotes α-synuclein toxicity How pathologic α-synuclein (α-syn) leads to neurodegeneration in Parkinson's disease (PD) remains poorly understood. Kam et al. studied the α-syn preformed fibril (α-syn PFF) model of sporadic PD (see the Perspe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd532fdb1d3ad3b98bdb6879d1df55f
https://doi.org/10.1126/science.aat8407
https://doi.org/10.1126/science.aat8407
Autor:
Gabsang Lee, Sangjune Kim, Xiaobo Mao, Xiling Yin, Seung-Hwan Kwon, Peter Rhee, Ted M. Dawson, Valina L. Dawson, Senthilkumar S. Karuppagounder, Hojae Lee, Dong-Hoon Kim, Han Seok Ko, George Essien Umanah, Veera Venkata Ratnam Bandaru, Akhilesh Pandey, Seung Pil Yun, Saebom Lee
Accumulating evidence suggests that α-synuclein (α-syn) occurs physiologically as a helically folded tetramer that resists aggregation. However, the mechanisms underlying the regulation of formation of α-syn tetramers are still mostly unknown. Cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ffaab84cda5a89832103f31fc648f41
https://europepmc.org/articles/PMC5789900/
https://europepmc.org/articles/PMC5789900/
Autor:
Yu Liang, Saurav Brahmachari, Valina L. Dawson, Sung Ung Kang, Creg J. Workman, Seung Pil Yun, Yulan Xiong, Ho Chul Kang, Xiling Yin, George Essien Umanah, Ted M. Dawson, Rong Chen, Senthilkumar S. Karuppagounder, Chen Qi, Nikhil Panicker, Sharon Lam, Jinchong Xu, Michael Tianhao Ou, Shaida A. Andrabi, Dario A. A. Vignali, Joel Tyson, Joo Ho Shin, Jianmin Zhang, Dong-Hoon Kim, Hyejin Park, Rafaella Araújo Gonçalves, James A. Keiler, Xiaobo Mao, Han Seok Ko, Shu Zhang, Preston Ge, Tae In Kam
Publikováno v:
Science (New York, N.Y.). 353(6307)
INTRODUCTION Parkinson’s disease (PD) is the second most common neurodegenerative disorder and leads to slowness of movement, tremor, rigidity, and, in the later stages of PD, cognitive impairment. Pathologically, PD is characterized by the accumul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::870b0163a8b475067bed9f2629b196bb
https://pubmed.ncbi.nlm.nih.gov/27708090
https://pubmed.ncbi.nlm.nih.gov/27708090
Autor:
Xiaobo Mao1,2,3 (AUTHOR), Ou, Michael Tianhao1,2 (AUTHOR), Karuppagounder, Senthilkumar S.1,2,3 (AUTHOR), Tae-In Kam1,2,3 (AUTHOR), Xiling Yin1,2,3 (AUTHOR), Yulan Xiong1,2,3,4 (AUTHOR), Ge, Preston1,2 (AUTHOR), Essien Umanah, George1,2,3 (AUTHOR), Brahmachari, Saurav1,2,3 (AUTHOR), Joo-Ho Shin1,2,5 (AUTHOR), Ho Chul Kang1,2,6 (AUTHOR), Jianmin Zhang1,2,7 (AUTHOR), Jinchong Xu\1,2,3 (AUTHOR), Rong Chen1,2,3 (AUTHOR), Hyejin Park1,2,3 (AUTHOR), Andrabi, Shaida A.1,2,3,8 (AUTHOR), Sung Ung Kang1,2,3 (AUTHOR), Araújo Gonçalves, Rafaella1,2,9 (AUTHOR), Yu Liang1,2 (AUTHOR), Shu Zhang1,2 (AUTHOR)
Publikováno v:
Science. 9/30/2016, Vol. 353 Issue 6307, paah3374-1-aah3374-12. 12p. 6 Graphs.