Výsledky vyhledávání - "George Ed, Rainger"

Akademický článek

PR3 and elastase alter PAR1 signaling and trigger vWF release via a calcium-independent mechanism from glomerular endothelial cells.

Autor: Samantha P Tull, Anne Bevins, Sahithi Jyothsna Kuravi, Simon C Satchell, Bahjat Al-Ani, Stephen P Young, Lorraine Harper, Julie M Williams, George Ed Rainger, Caroline O S Savage

Publikováno v: PLoS ONE, Vol 7, Iss 8, p e43916 (2012)

Neutrophil proteases, proteinase-3 (PR3) and elastase play key roles in glomerular endothelial cell (GEC) injury during glomerulonephritis. Endothelial protease-activated receptors (PARs) are potential serine protease targets in glomerulonephritis. W

Externí odkaz: https://doaj.org/article/a2e295cee5e945f693e5615d7542b4eb

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Podocytes regulate neutrophil recruitment by glomerular endothelial cells via IL-6-mediated crosstalk

Autor: Sahithi J, Kuravi, Helen M, McGettrick, Simon C, Satchell, Moin A, Saleem, Lorraine, Harper, Julie M, Williams, George Ed, Rainger, Caroline O S, Savage

Publikováno v: The Journal of Immunology Author Choice

Stromal cells actively modulate the inflammatory process, in part by influencing the ability of neighboring endothelial cells to support the recruitment of circulating leukocytes. We hypothesized that podocytes influence the ability of glomerular end

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7853ec017d1ce76df0d2a00dfcb9ef5d
https://pubmed.ncbi.nlm.nih.gov/24872191

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