Early cognitive development in children born to women with epilepsy: A prospective report

Autor: Jenna Love, Rebecca Bromley, Lauren McEwan, Jill Clayton-Smith, George E. Mawer, Laura Purdy, James Kelly, Gus A. Baker, Xin Sin, Maria Briggs

Publikováno v: Epilepsia. 51:2058-2065

Summary Purpose: In this prospective study the early cognitive development of children born to women with epilepsy (n = 198) was assessed and compared to a group of children representative of the general population (n = 230). Methods: The children we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f1d99ab37a18c3bac0c07def2b40b36e
https://doi.org/10.1111/j.1528-1167.2010.02668.x

IQ at 6 years after in utero exposure to anti epileptic drugs::A controlled cohort study

Autor: Gus A. Baker, Morris J. Cohen, Maria Briggs, Rebekah Shallcross, Rachel Kneen, Rebecca Bromley, Kimford J. Meador, Alison Gummery, Jill Clayton-Smith, George E. Mawer, Christopher P Cheyne, Marta García-Fiñana, David W. Loring

Publikováno v: Baker, G A, Bromley, R, Briggs, M, Cheyne, C P, Cohen, M J, García-Fiñana, M, Gummery, A, Kneen, R, Loring, D W, Mawer, G, Meador, K J, Shallcross, R & Clayton-Smith, J 2015, ' IQ at 6 years after in utero exposure to anti epileptic drugs: : A controlled cohort study ' Neurology, vol 84, no. 4, pp. 382-390 . DOI: 10.1212/WNL.0000000000001182
Neurology

Objective. To delineate the risk to child IQ associated with commonly prescribed antiepileptic drugs. Methods. Children born to women with epilepsy (n=243) and women without epilepsy (n=287) were recruited during pregnancy and followed prospectively.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d9ecb0ce46cb59fbd4d18bf3850bce
https://www.research.manchester.ac.uk/portal/en/publications/iq-at-6-years-after-in-utero-exposure-to-anti-epileptic-drugs(44c65618-a468-4e22-82a2-c8acebb0c2e9).html

The Long-Term Use of Gabapentin, Lamotrigine, and Vigabatrin in Patients with Chronic Epilepsy

Autor: George E. Mawer, David Chadwick, Josemir W. Sander, P. B. C. Fenwick, Ian C. K. Wong

Publikováno v: Epilepsia. 40:1439-1445

Summary: Purpose: To compare the long-term retention of gabapentin (GBP), lamotrigine (LTG), and vigabatrin (VGB) by patients with chronic epilepsy and the reasons for treatment discontinuation. To assess the likelihood of seizure freedom, seizure-re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3386191492b94f5e9470ae5054b33b84
https://doi.org/10.1111/j.1528-1157.1999.tb02017.x

The longer term outcome of children born to mothers with epilepsy

Autor: Jill Clayton-Smith, George E. Mawer, Paola Nicolaides, David Chadwick, Joanne Gorry, Usha Kini, Jon G Ayres, J. Vinten, J. Gregg, L Pickering, Gus A. Baker, Helen Coyle, L Tunnicliffe, N Adab, Alan Fryer

Objectives: To determine the prevalence of cognitive delay and possible associated dysmorphic features in children exposed to antiepileptic drugs (AEDs) in utero. Design: Retrospective study of children born to mothers with epilepsy. Setting: Regiona

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e731a9c1cd92bb0647c90ef9be397bd8
https://europepmc.org/articles/PMC1738809/

A pharmacoepidemiologic study of factors influencing the outcome of treatment with lamotrigine in chronic epilepsy

Autor: Samden D. Lhatoo, Josemir W. Sander, Ian C. K. Wong, George E. Mawer

Publikováno v: Epilepsia. 42(10)

Summary: Purpose: To identify prognostic factors for freedom from seizures and long-term retention of treatment in patients receiving lamotrigine (LTG). Methods: A multicenter, retrospective, case record study of 1,050 patients with chronic epilepsy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0d1ca734b007e7340a5ece6a8e7549
https://pubmed.ncbi.nlm.nih.gov/11737172