Zobrazeno 1 - 10
of 12
pro vyhledávání: '"George E Hucks"'
Autor:
Timothy J. Voorhees, Anne W. Beaven, Christopher Dittus, George E Hucks, J. Kaitlin Morrison, Catherine Joyce Arago Cheng, Tammy Cavallo, Steven I. Park, Gianpietro Dotti, Jonathan S. Serody, Barbara Savoldo, Natalie S. Grover
Publikováno v:
Blood. 140:12723-12724
Autor:
Jonathan S. Serody, Timothy J Voorhees, Natalie S Grover, Anne W. Beaven, Amir H. Khandani, Jennifer S. Smith, Catherine Cheng, J. Kaitlin Morrison, Anastasia Ivanova, George E Hucks, Beibo Zhao, Thomas B. Shea, Barbara Savoldo, Jorge Oldan, Gianpietro Dotti, Steven I. Park, Christopher Dittus
Publikováno v:
Blood advances. 6(4)
Our group has recently demonstrated that chimeric antigen receptor T-cell therapy targeting the CD30 antigen (CD30.CAR-T) is highly effective in patients with relapsed and refractory (r/r) classical Hodgkin lymphoma (cHL). Despite high rates of clini
Autor:
Michael Winstead, Thomas C. Shea, George E Hucks, J. Kaitlin Morrison, Marcie L. Riches, Anne W. Beaven, Natalie S Grover, Caroline Babinec, Gianpietro Dotti, Catherine Cheng, Arpita Patel, Barbara Savoldo, Jonathan S. Serody, Kimberly A. Kasow, Cammie Moore Presler
Publikováno v:
Blood. 138:2829-2829
Background: Chimeric antigen receptor (CAR)-T cell therapy targeting the CD19 antigen has been effective in treating B-cell acute lymphoblastic leukemia. As CAR-T cells targeting new antigens are being explored for the treatment of other cancers in a
Autor:
Philip A. Roehrs, Katarzyna Jamieson, J. Kaitlin Morrison, Gianpietro Dotti, Barbara Savoldo, Natalie S Grover, George E Hucks, Paul M. Armistead, Spencer Laing, Matthew C. Foster, Faith Brianne Buchanan, Jonathan S. Serody, Catherine Cheng
Publikováno v:
Blood. 136:36-37
Introduction: CAR-T cells targeting the CD19 antigen are approved to treat children and young adults with relapsed and refractory B-cell ALL, in whom response rates are >80%. Acute toxicities, including cytokine release syndrome (CRS) and immune effe
Autor:
George E Hucks, Susan R. Rheingold
Publikováno v:
Blood Cancer Journal
Blood Cancer Journal, Vol 9, Iss 2, Pp 1-9 (2019)
Blood Cancer Journal, Vol 9, Iss 2, Pp 1-9 (2019)
Outcomes of pediatric and young adult patients diagnosed with acute lymphoblastic leukemia (ALL) have improved significantly in the past few decades. Treatment advances have provided 5-year survival rates ranging from 78 to 91% depending on the age a
Autor:
Cammie Moore Presler, Arpita Patel, Joshua J. Bies, Timothy J. Vece, Kimberly A. Kasow, Michael Winstead, George E Hucks
Publikováno v:
Biology of Blood and Marrow Transplantation. 25:S316
Intro/Objectives Warts, hypogammaglobulinemia, infections, myelokathexis (WHIM) syndrome is a rare primary immunodeficiency defined by its symptoms and CXC chemokine receptor 4 (CXCR4) gene mutation. This leads to myelokathexis in which mature neutro
Autor:
Erika Mora, Ed Rothman, F. Jacob Seagull, George E Hucks, Schuyler Halverson, Kelly Walkovich, Kaleena Johnson, Michele M. Nypaver, Christopher A. Benner, John G. Younger, Emily L. Mueller
Publikováno v:
Pediatric emergency care. 34(5)
OBJECTIVES Febrile neutropenic pediatric patients are at heightened risk for serious bacterial infections, and rapid antibiotic administration (in
Autor:
Susan R. Rheingold, John Scholler, Katherine T. Marcucci, Jennifer Brogdon, Noelle V. Frey, George E Hucks, Simon F. Lacey, David L. Porter, Richard Aplenc, Pamela A. Shaw, Mala K. Talekar, Shannon L. Maude, Claire White, Colleen Callahan, Carl H. June, J. Joseph Melenhorst, Regina M. Young, Anne Chew, David T. Teachey, Stephan A. Grupp, David M. Barrett, Bruce L. Levine, Diane Baniewicz
Publikováno v:
Cytotherapy. 19:S9-S10
Autor:
Beth McBride, David T. Teachey, Stephan A. Grupp, Farzana Nazimuddin, Colleen Callahan, Simon F. Lacey, Diane Baniewicz, Vanessa E. Gonzalez, Amanda M. Li, Carl H. June, Alix E. Seif, Christina Fasano, George E Hucks, David L. Porter, Amanda M. DiNofia, Shannon L. Maude
Publikováno v:
Blood. 132:556-556
Abstract CAR T cell therapy in relapsed B-ALL can result in complete response (CR) rates of 80-90%, but relapse-free survival declines to 60% within the first 12-months due to both CD19-positive and negative relapses. CD19-positive relapses that occu
Autor:
Laura S Motley, J. Joseph Melenhorst, Colleen Callahan, David M. Barrett, George E Hucks, Susan R. Rheingold, Simon F. Lacey, Bruce L. Levine, David T. Teachey, Stephan A. Grupp, Diane Baniewicz, Mala K. Talekar, Claire White, Carl H. June, Shannon L. Maude
Publikováno v:
Journal of Clinical Oncology. 35:10507-10507
10507 Background: Anti-CD19 CAR-T cell therapies have shown high efficacy in inducing durable marrow responses in patients with relapsed/refractory CD19+ ALL. We now report on outcome of 10 patients with extramedullary (EM) involvement of ALL treated