Zobrazeno 1 - 10
of 51
pro vyhledávání: '"George Desmond Clark-Walker"'
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56465 (2013)
The mitochondrial genome maintenance gene, MGM101, is essential for yeasts that depend on mitochondrial DNA replication. Previously, in Saccharomyces cerevisiae, it has been found that the carboxy-terminal two-thirds of Mgm101p has a functional core.
Externí odkaz:
https://doaj.org/article/bd91d0b4363e4eb3bbbe429b0ccd771b
Publikováno v:
Mitochondrion. 38:17-22
Conventional DNA replication is initiated from specific origins and requires the synthesis of RNA primers for both the leading and lagging strands. In contrast, the replication of yeast mitochondrial DNA is origin-independent. The replication of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af6e34535e220c18db3d75d8f6fa8d06
https://doi.org/10.1016/j.mito.2017.07.009
https://doi.org/10.1016/j.mito.2017.07.009
Publikováno v:
FEMS Yeast Research. 7:131-140
Analysis of Mgm101p isolated from mitochondria shows that the mature protein of 27.6 kDa lacks 22 amino acids from the N-terminus. This mitochondrial targeting sequence has been incorporated in the design of oligonucleotides used to determine a funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::577c58262fdc4264fa2b94afc6def23b
https://doi.org/10.1111/j.1567-1364.2006.00141.x
https://doi.org/10.1111/j.1567-1364.2006.00141.x
Publikováno v:
Genetics. 159:929-938
Loss of mtDNA or mitochondrial protein synthesis cannot be tolerated by wild-type Kluyveromyces lactis. The mitochondrial function responsible for ρ0-lethality has been identified by disruption of nuclear genes encoding electron transport and F0-ATP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c640af4af9950fa53a71c6ebda21b454
https://doi.org/10.1093/genetics/159.3.929
https://doi.org/10.1093/genetics/159.3.929
Publikováno v:
Journal of Biological Chemistry. 275:14865-14872
The nuclear gene encoding the Sit4 protein phosphatase was identified in the budding yeast Kluyveromyces lactis. K. lactis cells carrying a disrupted sit4 allele are resistant to oligomycin, antimycin, ketoconazole, and econazole but hypersensitive t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb1dda2e858ceac43886062409a5fd2f
https://doi.org/10.1074/jbc.275.20.14865
https://doi.org/10.1074/jbc.275.20.14865
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1478:125-137
Characterisation of 35 Kluyveromyces lactis strains lacking mitochondrial DNA has shown that mutations suppressing rho(0)-lethality are limited to the ATP1, 2 and 3 genes coding for the alpha-, beta- and gamma- subunits of mitochondrial F(1)-ATPase.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64007ef9f6149ac59590bdeac020185
https://doi.org/10.1016/s0167-4838(00)00003-0
https://doi.org/10.1016/s0167-4838(00)00003-0
Publikováno v:
Current Genetics. 33:46-51
Kluyveromyces lactis is a petite-negative yeast that does not form viable mitochondrial genome-deletion mutants (petites) when treated with DNA-targeting drugs. Loss of mtDNA is lethal for this yeast but mutations at three loci termed MGI, for mitoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::860f6a0ebfa9b0bd2cd354988b8f657c
https://doi.org/10.1007/s002940050307
https://doi.org/10.1007/s002940050307
F 1 -ATPase is a rotary molecular machine with a subunit stoichiometry of α 3 β 3 γ 1 δ 1 ε 1 . It has a robust ATP-hydrolyzing activity due to effective cooperativity between the three catalytic sites. It is believed that the central γ rotor d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c966880b331def1c151f4cc3f68483
https://europepmc.org/articles/PMC3837939/
https://europepmc.org/articles/PMC3837939/
The N-Terminal Intrinsically Disordered Domain of Mgm101p Is Localized to the Mitochondrial Nucleoid
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 2, p e56465 (2013)
PLoS ONE, Vol 8, Iss 2, p e56465 (2013)
The mitochondrial genome maintenance gene, MGM101, is essential for yeasts that depend on mitochondrial DNA replication. Previously, in Saccharomyces cerevisiae, it has been found that the carboxy-terminal two-thirds of Mgm101p has a functional core.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd22555f61732da18fb7716b2f491c70
http://europepmc.org/articles/PMC3572067
http://europepmc.org/articles/PMC3572067
Publikováno v:
Current Genetics. 20:99-114
The cytochrome oxidase subunit 1 gene (COX1) in K. lactis K8 mtDNA spans 8,826 bp and contains five exons (termed E1-E5) totalling 1,602 bp that show 88% nucleotide base matching and 91% amino acid homology to the equivalent gene in S. cerevisiae. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b709dd9f88c57d287ca613a30c1485e0
https://doi.org/10.1007/bf00312772
https://doi.org/10.1007/bf00312772