Zobrazeno 1 - 10
of 13
pro vyhledávání: '"George Daaboul"'
Autor:
Jerome Nouvel, Gonzalo Bustos Quevedo, Tony Prinz, Ramsha Masood, George Daaboul, Tanja Gainey‐Schleicher, Uwe Wittel, Sophia Chikhladze, Bence Melykuti, Martin Helmstaedter, Karl Winkler, Irina Nazarenko, Gerhard Pütz
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 10, Pp n/a-n/a (2024)
Abstract Extracellular vesicles (EVs) are valuable targets for liquid biopsy. However, attempts to introduce EV‐based biomarkers into clinical practice have not been successful to the extent expected. One of the reasons for this failure is the lack
Externí odkaz:
https://doaj.org/article/588507e5d9a54be8a0d1eefab47b6573
Autor:
Zachary C. Elmore, L. Patrick Havlik, Daniel K. Oh, Leif Anderson, George Daaboul, Garth W. Devlin, Heather A. Vincent, Aravind Asokan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Adeno-associated viruses can be secreted in a pre-lytic manner as free or extracellular vesicle (EV)-associated particles. Here, Elmore et al. show that the recently identified membrane-associated accessory protein (MAAP) functions as an AAV egress f
Externí odkaz:
https://doaj.org/article/77164043657048c7a3dd23f08da5097f
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 9, Pp n/a-n/a (2022)
Abstract CD47 regulates the trafficking of specific coding and noncoding RNAs into extracellular vesicles (EVs), and the RNA contents of CD47+ EVs differ from that of CD63+ EVs released by the same cells. Single particle interferometric reflectance i
Externí odkaz:
https://doaj.org/article/a8ba02e1a151407d841454c1433a182e
Autor:
Andreia M. Silva, Elisa Lázaro‐Ibáñez, Anders Gunnarsson, Aditya Dhande, George Daaboul, Ben Peacock, Xabier Osteikoetxea, Nikki Salmond, Kristina Pagh Friis, Olga Shatnyeva, Niek Dekker
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 10, Pp n/a-n/a (2021)
Abstract Extracellular Vesicles (EVs) have been intensively explored for therapeutic delivery of proteins. However, methods to quantify cargo proteins loaded into engineered EVs are lacking. Here, we describe a workflow for EV analysis at the single
Externí odkaz:
https://doaj.org/article/2ca44902d95e4a328a40c83c1e76dc25
Autor:
Ling Huang, Bruno Bockorny, Indranil Paul, Dipikaa Akshinthala, Pierre-Oliver Frappart, Omar Gandarilla, Arindam Bose, Veronica Sanchez-Gonzalez, Emily E. Rouse, Sylvain D. Lehoux, Nicole Pandell, Christine M. Lim, John G. Clohessy, Joseph Grossman, Raul Gonzalez, Sofia Perea Del Pino, George Daaboul, Mandeep S. Sawhney, Steven D. Freedman, Alexander Kleger, Richard D. Cummings, Andrew Emili, Lakshmi B. Muthuswamy, Manuel Hidalgo, Senthil K. Muthuswamy
Publikováno v:
JCI Insight, Vol 5, Iss 21 (2020)
Patient-derived organoid models are proving to be a powerful platform for both basic and translational studies. Here we conduct a methodical analysis of pancreatic ductal adenocarcinoma (PDAC) tumor organoid drug response in paired patient-derived xe
Externí odkaz:
https://doaj.org/article/ece33f7ae51a4b3987a1856d60d1d5c9
Autor:
Aled Clayton, Dominik Buschmann, J. Brian Byrd, David R. F. Carter, Lesley Cheng, Carolyn Compton, George Daaboul, Andrew Devitt, Juan Manuel Falcon-Perez, Chris Gardiner, Dakota Gustafson, Paul Harrison, Clemens Helmbrecht, An Hendrix, Andrew Hill, Andrew Hoffman, Jennifer C. Jones, Raghu Kalluri, Ji Yoon Kang, Benedikt Kirchner, Cecilia Lässer, Charlotte Lawson, Metka Lenassi, Carina Levin, Alicia Llorente, Elena S. Martens-Uzunova, Andreas Möller, Luca Musante, Takahiro Ochiya, Ryan C Pink, Hidetoshi Tahara, Marca H. M. Wauben, Jason P. Webber, Joshua A. Welsh, Kenneth W. Witwer, Hang Yin, Rienk Nieuwland
Publikováno v:
Journal of Extracellular Vesicles, Vol 7, Iss 1 (2018)
This report summarises the presentations and activities of the ISEV Workshop on extracellular vesicle biomarkers held in Birmingham, UK during December 2017. Among the key messages was broad agreement about the importance of biospecimen science. Much
Externí odkaz:
https://doaj.org/article/7aa258f6366b42db8a466d43b6532a32
Autor:
Kai Härkönen, Sanna Oikari, Heikki Kyykallio, Janne Capra, Sini Hakkola, Kirsi Ketola, Uma Thanigai Arasu, George Daaboul, Andrew Malloy, Carla Oliveira, Otto Jokelainen, Reijo Sironen, Jaana M. Hartikainen, Kirsi Rilla
Publikováno v:
Cells, Vol 8, Iss 3, p 276 (2019)
CD44 is a multifunctional adhesion molecule typically upregulated in malignant, inflamed and injured tissues. Due to its ability to bind multiple ligands present in the tumor microenvironment, it promotes multiple cellular functions related to tumori
Externí odkaz:
https://doaj.org/article/1f935e40bb864eb1950432ca6fa63532
Autor:
Priyanka Gokulnath, Michail Spanos, H. Immo Lehmann, Quanhu Sheng, Rodosthenis Rodosthenous, Mark Chaffin, Dimitrios Varrias, Emeli Chatterjee, Elizabeth Hutchins, Guoping Li, George Daaboul, Farhan Rana, Ashley Mingyi Wang, Kendall Van Keuren-Jensen, Patrick T. Ellinor, Ravi Shah, Saumya Das
Publikováno v:
medRxiv
BackgroundAcute decompensation is associated with increased mortality in heart failure (HF) patients, though the underlying etiology remains unclear. Extracellular vesicles (EVs) and their cargo may mark specific cardiovascular physiologic states. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ae5d2fc0c9d55e47da5f47eeac5cebb
https://doi.org/10.1101/2023.02.17.23285936
https://doi.org/10.1101/2023.02.17.23285936
Autor:
Wei Zhang, Wenqun Zhong, Beike Wang, Jiegang Yang, Jingbo Yang, Ziyan Yu, Zhiyuan Qin, Alex Shi, Wei Xu, Cathy Zheng, Lynn M. Schuchter, Giorgos C. Karakousis, Tara C. Mitchell, Ravi Amaravadi, Meenhard Herlyn, Haidong Dong, Phyllis A. Gimotty, George Daaboul, Xiaowei Xu, Wei Guo
Publikováno v:
Dev Cell
Tumor-derived extracellular vesicles (TEVs) suppress the proliferation and cytotoxicity of CD8(+) T cells, thereby contributing to tumor immune evasion. Here we report that the adhesion molecule ICAM-1 co-localizes with PD-L1 on the exosomes; both IC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1bfc7447478166edf18663039c19655
https://europepmc.org/articles/PMC8881799/
https://europepmc.org/articles/PMC8881799/
Autor:
Leif G. Anderson, Garth Devlin, Daniel K. Oh, L. Patrick Havlik, George Daaboul, Aravind Asokan, Zachary C. Elmore, Heather A. Vincent
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Adeno-associated viruses (AAV) rely on helper viruses to transition from latency to lytic infection. Some AAV serotypes are secreted in a pre-lytic manner as free or extracellular vesicle (EV)-associated particles, although mechanisms underlying such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2db268b47dd74b117ab8a2a9e7103216
https://pubmed.ncbi.nlm.nih.gov/34716331
https://pubmed.ncbi.nlm.nih.gov/34716331