Zobrazeno 1 - 10
of 34
pro vyhledávání: '"George D. Prell"'
Autor:
V L Friedrich, Giorgio P. Martinelli, Ozlem Bozdagi, George D. Prell, G. R. Holstein, George W. Huntley, X. B. Wang
Publikováno v:
Journal of Neurophysiology. 105:1266-1275
Imidazole-4-acetic acid-ribotide (IAA-RP), an endogenous agonist at imidazoline receptors (I-Rs), is a putative neurotransmitter/regulator in mammalian brain. We studied the effects of IAA-RP on excitatory transmission by performing extracellular and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::913f7dc89c35c834adcab0b7f2799105
https://doi.org/10.1152/jn.00263.2010
https://doi.org/10.1152/jn.00263.2010
Autor:
George D. Prell, Boban Thomas
Publikováno v:
Journal of Neurochemistry. 65:818-826
It is generally accepted that in mammalian brain histamine is metabolized solely by histamine methyltransferase (HMT), to form tele-methylhistamine, then oxidized to tele-methylimidazoleacetic acid. However, histamine's oxidative metabolite in the pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea6c6cbcc97198522c0a5126e92f358e
https://doi.org/10.1046/j.1471-4159.1995.65020818.x
https://doi.org/10.1046/j.1471-4159.1995.65020818.x
Publikováno v:
Journal of Neurochemistry. 66:2153-2159
In mammalian brain, histamine is known to be metabolized solely by histamine methyltransferase (HMT), forming tele-methylhistamine (t-MH), then tele-methylimidazoleacetic acid (t-MIAA). We previously showed that imidazoleacetic acid (IAA), a GABA ago
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::243703ba96e18fb0d2205c6c9701f250
https://doi.org/10.1046/j.1471-4159.1996.66052153.x
https://doi.org/10.1046/j.1471-4159.1996.66052153.x
Publikováno v:
Journal of Neurochemistry. 68:142-151
In brain, the precursor of imidazoleacetic acid (IAA), a GABAA agonist but a GABAC antagonist, is not known. In the periphery, IAA derives from oxidation of histamine. But in brain, histamine is thought to be metabolized solely by histamine methyltra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e6e90c765b9428aa0c77743327aca3e
https://doi.org/10.1046/j.1471-4159.1997.68010142.x
https://doi.org/10.1046/j.1471-4159.1997.68010142.x
Publikováno v:
Experimental Neurology. 136:12-21
This study was performed to investigate the physicological properties of histaminergic neurons in intraocular hypothalamic transplants. Pieces of posterolateral hypothalamus containing the tuberomammillary nucleus were dissected from Embryonic Day 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1461798e1fd08f0b8a99159ed3cc6879
https://doi.org/10.1006/exnr.1995.1079
https://doi.org/10.1006/exnr.1995.1079
Autor:
Charles A. Kaufmann, Markku Linnoila, Jack Peter Green, Darrell G. Kirch, George D. Prell, Albert M. Morrishow, Richard Jed Wyatt, Jai K. Khandelwal
Publikováno v:
Schizophrenia Research. 14:93-104
Levels of the histamine metabolites, tele-methylhistamine (t-MH) and tele-methylimidazoleacetic acid (t-MIAA), and metabolites of other aminergic transmitters and of norepinephrine were measured in cerebrospinal fluid of 36 inpatients with chronic sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb4fa1e13f0404f4de145af3f596638
https://doi.org/10.1016/0920-9964(94)00034-6
https://doi.org/10.1016/0920-9964(94)00034-6
Publikováno v:
Neurology. 55:1222-1224
The authors induced a transient Wernicke's aphasia in a patient with left frontal arteriovenous malformation by superselective Wada injection exclusively into the lower division of the left middle cerebral artery. The patient was then asked to recall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf573df9944eaa81c2bb74f0a8d591e3
https://doi.org/10.1212/wnl.55.8.1222
https://doi.org/10.1212/wnl.55.8.1222
Autor:
George D. Prell, Albert M. Morrishow, R. S. Burns, Patrizio Blandina, Jai K. Khandelwal, Jack Peter Green
Publikováno v:
Journal of Neural Transmission - Parkinson's Disease and Dementia Section. 3:109-125
The cerebrospinal fluid (CSF) levels of pros-methylimidazoleacetic acid (p-MIAA) in thirteen medication-free patients with mild to moderate Parkinson's disease were highly correlated (Spearman's rho = 0.749, p less than 0.005) with the severity of si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6243c9b1702cedbc9a909492d6e77f8
https://doi.org/10.1007/bf02260886
https://doi.org/10.1007/bf02260886
Autor:
George D. Prell
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 29:111-115
15N,15N-imidazoleacetic acid was synthesized from 15N, 15N-DL-histidine (>99 atom % 15N). The latter, oxidized with sodium hypochiorite, formed 15N,15N-imidazoleacetonitrile. The free acid was prepared after acid hydrolysis of the nitrile, elution fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b67b0a164dc113dd149b172dac567ea8
https://doi.org/10.1002/jlcr.2580290115
https://doi.org/10.1002/jlcr.2580290115
Publikováno v:
Archives of Gerontology and Geriatrics. 12:1-12
The metabolites of histamine, tele-methylhistamine (t-MH) and tele-methylimidazoleacetic acid (t-MIAA), were measured in cerebrospinal fluid (CSF) from 47 subjects with neurological disorders and healthy controls. In lumbar CSF, concentrations of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad64b79e0918e10058b9771c0d56bb68
https://doi.org/10.1016/0167-4943(91)90002-8
https://doi.org/10.1016/0167-4943(91)90002-8