Zobrazeno 1 - 10
of 288
pro vyhledávání: '"George D Wilson"'
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 38, Iss , Pp 104-110 (2023)
Introduction: In this pilot study we have taken a novel functional approach to assess whether differences exist in the activity of key genes involved in the response to radiation and oxidative stress between patients with radiation cystitis. Material
Externí odkaz:
https://doaj.org/article/c2c2e4131d814db78131beae93b046b7
Autor:
Lee F Peoples
Publikováno v:
International Journal of Legal Information. 38:405-407
Autor:
George D. Wilson, Thomas G. Wilson, Alaa Hanna, Mohamad Dabjan, Katie Buelow, John Torma, Brian Marples, Sandra Galoforo
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 26, Iss , Pp 15-23 (2021)
Background and purpose: There has been little success targeting individual genes in combination with radiation in head and neck cancer. In this study we investigated whether targeting two key pathways simultaneously might be more effective. Materials
Externí odkaz:
https://doaj.org/article/3d7c6b9219014de496ae577fd150267e
Publikováno v:
MethodsX, Vol 6, Iss , Pp 1286-1291 (2019)
Molecular Interaction Network Approach (MINA) was used to elucidate candidate disease genes. The approach was implemented to identify novel gene association with commonly known autoimmune diseases [1]. In MINA, we evaluated the hypothesis that “net
Externí odkaz:
https://doaj.org/article/538e143ff9a34208a799579461359d2d
Autor:
Ray O Bahado-Singh, Sangeetha Vishweswaraiah, Buket Aydas, Ali Yilmaz, Raghu P Metpally, David J Carey, Richard C Crist, Wade H Berrettini, George D Wilson, Khalid Imam, Michael Maddens, Halil Bisgin, Stewart F Graham, Uppala Radhakrishna
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248375 (2021)
We evaluated the utility of leucocyte epigenomic-biomarkers for Alzheimer's Disease (AD) detection and elucidates its molecular pathogeneses. Genome-wide DNA methylation analysis was performed using the Infinium MethylationEPIC BeadChip array in 24 l
Externí odkaz:
https://doaj.org/article/d9537ca420cb4d748465ee176c2f4948
Autor:
Kevin Blas, Thomas G. Wilson, Nathan Tonlaar, Sandra Galoforo, Alaa Hana, Brian Marples, George D. Wilson
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 11, Iss , Pp 1-10 (2018)
Background and purpose: In this study we have combined fractionated radiation treatment (RT) with two molecular targeted agents active against key deregulated signaling pathways in head and neck cancer. Materials and methods: We used two molecularly
Externí odkaz:
https://doaj.org/article/b3e43db43440445898e71d315a92a086
Autor:
Prakash Chinnaiyan, C. Ryan Miller, George D. Wilson, Katie L. Buelow, Stewart F. Graham, Praveen Kumar, Shiva Kant, Antony Prabhu, Pravin Kesarwani
Supplemental Figures 1, 2, 3 and 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dadb4332afc63c53352cc36e44e0b55
https://doi.org/10.1158/1078-0432.22470348
https://doi.org/10.1158/1078-0432.22470348
Autor:
Prakash Chinnaiyan, C. Ryan Miller, George D. Wilson, Katie L. Buelow, Stewart F. Graham, Praveen Kumar, Shiva Kant, Antony Prabhu, Pravin Kesarwani
Supplementary Methods with description on Microarray analysis, Tumor models, Kynurenine estimation, Western Blotting, LC-MS and Flow cytometry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::157c827c4318ca5b332a591da7597072
https://doi.org/10.1158/1078-0432.22470345.v1
https://doi.org/10.1158/1078-0432.22470345.v1
Autor:
Prakash Chinnaiyan, C. Ryan Miller, George D. Wilson, Katie L. Buelow, Stewart F. Graham, Praveen Kumar, Shiva Kant, Antony Prabhu, Pravin Kesarwani
Purpose: Immune checkpoint inhibitors designed to revert tumor-induced immunosuppression have emerged as potent anticancer therapies. Tryptophan metabolism represents an immune checkpoint, and targeting this pathway's rate-limiting enzyme IDO1 is act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ba580291ee898eb8f3e43e00e5093d
https://doi.org/10.1158/1078-0432.c.6527529
https://doi.org/10.1158/1078-0432.c.6527529
Autor:
Frank Verhaegen, Karl T Butterworth, Anthony J Chalmers, Rob P Coppes, Dirk de Ruysscher, Sophie Dobiasch, John D Fenwick, Patrick V Granton, Stefan H J Heijmans, Mark A Hill, Constantinos Koumenis, Kirsten Lauber, Brian Marples, Katia Parodi, Lucas C G G Persoon, Nick Staut, Anna Subiel, Rianne D W Vaes, Stefan van Hoof, Ioannis L Verginadis, Jan J Wilkens, Kaye J Williams, George D Wilson, Ludwig J Dubois
Publikováno v:
Physics in Medicine and Biology, 68(6). IOP Publishing Ltd.
Verhaegen, F, Butterworth, K T, Chalmers, A J, Coppes, R P, de Ruysscher, D, Dobiasch, S, Fenwick, J D, Granton, P V, Heijmans, S H J, Hill, M A, Koumenis, C, Lauber, K, Marples, B, Parodi, K, Persoon, L C G G, Staut, N, Subiel, A, Vaes, R D W, van Hoof, S, Verginadis, I L, Wilkens, J J, Williams, K J & Wilson, G D 2023, ' Roadmap for precision preclinical x-ray radiation studies ', Physics in Medicine and Biology, vol. 68, no. 6, 06RM01 . https://doi.org/10.1088/1361-6560/acaf45
Verhaegen, F, Butterworth, K T, Chalmers, A J, Coppes, R P, de Ruysscher, D, Dobiasch, S, Fenwick, J D, Granton, P V, Heijmans, S H J, Hill, M A, Koumenis, C, Lauber, K, Marples, B, Parodi, K, Persoon, L C G G, Staut, N, Subiel, A, Vaes, R D W, van Hoof, S, Verginadis, I L, Wilkens, J J, Williams, K J & Wilson, G D 2023, ' Roadmap for precision preclinical x-ray radiation studies ', Physics in Medicine and Biology, vol. 68, no. 6, 06RM01 . https://doi.org/10.1088/1361-6560/acaf45
This Roadmap paper covers the field of precision preclinical x-ray radiation studies in animal models. It is mostly focused on models for cancer and normal tissue response to radiation, but also discusses other disease models. The recent technologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05103f95458dc0a4608333fb04c34423
https://cris.maastrichtuniversity.nl/en/publications/ec5c3a0a-a978-4f52-b112-e310333f3236
https://cris.maastrichtuniversity.nl/en/publications/ec5c3a0a-a978-4f52-b112-e310333f3236