Transcriptome analysis identifies an ASD-Like phenotype in oligodendrocytes and microglia from C58/J amygdala that is dependent on sex and sociability

Autor: George D. Dalton, Stephen K. Siecinski, Viktoriya D. Nikolova, Gary P. Cofer, Kathryn J. Hornburg, Yi Qi, G. Allan Johnson, Yong-Hui Jiang, Sheryl S. Moy, Simon G. Gregory

Publikováno v: Behavioral and Brain Functions, Vol 20, Iss 1, Pp 1-23 (2024)

Abstract Background Autism Spectrum Disorder (ASD) is a group of neurodevelopmental disorders with higher incidence in males and is characterized by atypical verbal/nonverbal communication, restricted interests that can be accompanied by repetitive b

Externí odkaz: https://doaj.org/article/3a0dc3d8da37446598bf596a2a78dc61

CB1 Cannabinoid Receptors Stimulate Gβγ-GRK2-Mediated FAK Phosphorylation at Tyrosine 925 to Regulate ERK Activation Involving Neuronal Focal Adhesions

Autor: George D. Dalton, Skyla T. Carney, Jamie D. Marshburn, Derek C. Norford, Allyn C. Howlett

Publikováno v: Frontiers in Cellular Neuroscience, Vol 14 (2020)

CB1 cannabinoid receptors (CB1) are abundantly expressed in the nervous system where they regulate focal adhesion kinase (FAK) and the mitogen-activated protein kinases (MAPK) extracellular signal-regulated kinase 1 and 2 (ERK1/2). However, the role

Externí odkaz: https://doaj.org/article/3ec6c09a164b4384b31f85d5d9a5f6b7

Aging reduces liver resiliency by dysregulating Hedgehog signaling

Autor: Raquel Maeso‐Díaz, George D. Dalton, Sehhoon Oh, Kuo Du, Linda Tang, Tianyi Chen, Rajesh K. Dutta, Jessica H. Hartman, Joel N. Meyer, Anna Mae Diehl

Publikováno v: Aging Cell. 21

Older age is a major risk factor for damage to many tissues, including liver. Aging undermines resiliency and impairs liver regeneration. The mechanisms whereby aging reduces resiliency are poorly understood. Hedgehog is a signaling pathway with crit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9303b965c73dc20957bb3c8eab5f051
https://doi.org/10.1111/acel.13530

CB

Autor: George D, Dalton, Skyla T, Carney, Jamie D, Marshburn, Derek C, Norford, Allyn C, Howlett

Publikováno v: Frontiers in Cellular Neuroscience

CB1 cannabinoid receptors (CB1) are abundantly expressed in the nervous system where they regulate focal adhesion kinase (FAK) and the mitogen-activated protein kinases (MAPK) extracellular signal-regulated kinase 1 and 2 (ERK1/2). However, the role

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f7a07afefa07eb298f74386b28efe0bd
https://pubmed.ncbi.nlm.nih.gov/32655375

Soluble klotho binds monosialoganglioside to regulate membrane microdomains and growth factor signaling

Autor: George D. Dalton, Nicole Nischan, Evgenia Dobrinskikh, Joonho Yoon, Donald W. Hilgemann, Jennifer J. Kohler, Lutz Birnbaumer, Katherine Luby-Phelps, Saif I. Al-Juboori, Jian Xie, Sung Wan An, Chou Long Huang

Publikováno v: Proceedings of the National Academy of Sciences. 2017;114(4):752-757
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA

Fil: Dalton, George. University of Texas Southwestern Medical Center. Department of Medicine; Estados Unidos Fil: An, Sung-Wan. University of Texas Southwestern Medical Center. Department of Medicine; Estados Unidos Fil: Al-Juboori, Saif I. Universit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::418a27a974f6bbac2f709ea82a4a43d7
https://repositorio.uca.edu.ar/handle/123456789/8734