Zobrazeno 1 - 9
of 9
pro vyhledávání: '"George Crotts"'
Autor:
Klaus Wuchner, Linda Yi, Cyrille Chery, Felix Nikels, Friederike Junge, George Crotts, Gianluca Rinaldi, Jason A. Starkey, Karoline Bechtold-Peters, Melissa Shuman, Michael Leiss, Michael Jahn, Patrick Garidel, Rien de Ruiter, Sarah M. Richer, Shawn Cao, Sebastian Peuker, Sylvain Huille, Tingting Wang, Virginie Le Brun
Publikováno v:
Journal of Pharmaceutical Sciences. 111:2955-2967
Polysorbate (PS) 20 and 80 are the main surfactants used to stabilize biopharmaceutical products. Industry practices on various aspects of PS based on a confidential survey and following discussions by 16 globally acting major biotechnology companies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea8521e83744774d4dca728dc73db0b
https://doi.org/10.1016/j.xphs.2022.08.021
https://doi.org/10.1016/j.xphs.2022.08.021
Autor:
Klaus Wuchner, Linda Yi, Cyrille Chery, Felix Nikels, Friederike Junge, George Crotts, Gianluca Rinaldi, Jason A. Starkey, Karoline Bechtold-Peters, Melissa Shuman, Michael Leiss, Michael Jahn, Patrick Garidel, Rien de Ruiter, Sarah M Richer, Shawn Cao, Sebastian Peuker, Sylvain Huille, Tingting Wang, Virginie Le Brun
Publikováno v:
Journal of pharmaceutical sciences. 111(5)
Polysorbates (PS) are widely used as a stabilizer in biopharmaceutical products. Industry practices on various aspects of PS are presented in this part 1 survey report based on a confidential survey and following discussions by 16 globally acting maj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fabf14b911f2e159c164b7a11a62373
https://pubmed.ncbi.nlm.nih.gov/35192858
https://pubmed.ncbi.nlm.nih.gov/35192858
Autor:
Shubhadra N. Singh, George Crotts, Tanvir Tabish, Qingyan Hu, Brittney J. Mills, Lori S. Burton, Douglas E. Kamen, Hodge Tamara Shafer, Yongmei Wu, Francisca O. Gbormittah, Sonal Saluja, Elaine S.E. Stokes, Kevin Muthurania, Adithi C. Bhargava, Chakravarthy Nachu Narasimhan, Ligi Mathews
Publikováno v:
Journal of pharmaceutical sciences. 111(4)
In-use stability and compatibility studies are often used in biotherapeutic development to assess stability and compatibility of biologic drugs with diluents and/or administration components at relevant conditions for the target route of administrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1df8538532608b92255c19f48603c61c
https://pubmed.ncbi.nlm.nih.gov/34600941
https://pubmed.ncbi.nlm.nih.gov/34600941
Autor:
Peter M. Ihnat, Katherine Taylor, Chakravarthy Nachu Narasimhan, Dingjiang Liu, Valentyn Antochshuk, Jason E. Fernandez, Kapil Gupta, Daniel Dix, Eric Routhier, Elaine S.E. Stokes, Truong Nobel T, Sorina Morar-Mitrica, Fleming Michael, James K. Kranz, Diluzio Willow, Christine Wurth, George Crotts, Bing He, Monica L. Adams, Tanvir Tabish
Publikováno v:
Journal of pharmaceutical sciences. 107(2)
The Biophorum Development Group (BPDG) is an industry-wide consortium enabling networking and sharing of best practices for the development of biopharmaceuticals. To gain a better understanding of current industry approaches for establishing biopharm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061474570a3b0f2fc78623421fb44679
https://pubmed.ncbi.nlm.nih.gov/29074375
https://pubmed.ncbi.nlm.nih.gov/29074375
Autor:
Douglas P. Nesta, Ping Hu, Alexandra Beumer Sassi, George Crotts, Sorina Morar-Mitrica, Joshua Fuller, Manasi Puri
Publikováno v:
mAbs. 7(4)
The physical and chemical integrity of a biopharmaceutical must be maintained not only during long-term storage but also during administration. Specifically for the intravenous (i.v.) delivery of a protein drug, loss of stability can occur when the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adff940c86a5584606773e54eac26c95
https://pubmed.ncbi.nlm.nih.gov/26073995
https://pubmed.ncbi.nlm.nih.gov/26073995
Publikováno v:
Journal of Controlled Release. 47:101-111
A model protein, carboxymethylated bovine serum albumin (CM-BSA), was encapsulated within relatively fast degrading and slow degrading poly(d,l-lactide-co-glycolide, PLGA) microspheres using a multiple emulsion solvent evaporation technique. The spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b57abca85dff2c71311ce7ae4eb5224
https://doi.org/10.1016/s0168-3659(96)01624-0
https://doi.org/10.1016/s0168-3659(96)01624-0
Autor:
George Crotts, Tae Gwan Park
Publikováno v:
Journal of Controlled Release. 44:123-134
Various factors affecting the stability and release of a model protein, bovine serum albumin (BSA), encapsulated within biodegradable poly( d , l -lactide-co-glycolide) microparticles were examined in detail. Size exclusion chromatographic analysis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da01c12e89ccb042ed32f014c875039a
https://doi.org/10.1016/s0168-3659(96)01511-8
https://doi.org/10.1016/s0168-3659(96)01511-8
Autor:
Tae Gwan Park, George Crotts
Publikováno v:
Journal of Controlled Release. 35:91-105
A simple method to prepare various porous and nonporous hollow microspheres composed of poly( d,l -lactic-co-glycolic acid) using a water/oil/water (W/O/W) multiple emulsion solvent evaporation technique is described. The volume of the inner aqueous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffe2ade035631265ac6488bbc3a03615
https://doi.org/10.1016/0168-3659(95)00010-6
https://doi.org/10.1016/0168-3659(95)00010-6
Publikováno v:
Journal of Controlled Release. 33:211-222
Two proteins, carbonic anhydrase (Mr 31 000) and bovine serum albumin (Mr 66 000), have been encapsulated as model protein drugs within microspheres composed of relatively fast degrading poly(d,l-lactic acid-co-glycolic acid, 50/50). The microspheres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::050e988db8a88942f57cfb03846af9ac
https://doi.org/10.1016/0168-3659(94)00084-8
https://doi.org/10.1016/0168-3659(94)00084-8