Zobrazeno 1 - 10
of 123
pro vyhledávání: '"George Chu"'
Publikováno v:
Non-Coding RNA, Vol 9, Iss 1, p 14 (2023)
Epithelial-to-mesenchymal transition (EMT) is critical to cutaneous wound healing. When skin is injured, EMT activates and mobilizes keratinocytes toward the wound bed, therefore enabling re-epithelialization. This process becomes dysregulated in pat
Externí odkaz:
https://doaj.org/article/392b4f9610b9406aadb2883843c11dd1
Autor:
Fei Fang, George Chu Liu, Xiaohua Zhou, Stuart Yang, Heather Naomi Reich, Vanessa Williams, Amanda Hu, Janice Pan, Ana Konvalinka, Gavin Yadram Oudit, James William Scholey, Rohan John
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71433 (2013)
Ischemia-reperfusion (I/R) is a model of acute kidney injury (AKI) that is characterized by vasoconstriction, oxidative stress, apoptosis and inflammation. Previous studies have shown that activation of the renin-angiotensin system (RAS) may contribu
Externí odkaz:
https://doaj.org/article/791fed6321854d9d988a12138323df36
Autor:
Zhang, Liping1 (AUTHOR), Hung, George Chu-Chih1 (AUTHOR), Meng, Songmei1 (AUTHOR), Evans, Robin2 (AUTHOR), Xu, Junwang1 (AUTHOR) jxu61@uthsc.edu
Publikováno v:
Non-Coding RNA. Feb2023, Vol. 9 Issue 1, p14. 11p.
Autor:
Jiwoon Park, Eliah G. Overbey, S. Anand Narayanan, JangKeun Kim, Braden T. Tierney, Namita Damle, Deena Najjar, Krista A. Ryon, Jacqueline Proszynski, Ashley Kleinman, Jeremy Wain Hirschberg, Matthew MacKay, Evan E. Afshin, Richard Granstein, Justin Gurvitch, Briana M. Hudson, Aric Rininger, Sean Mullane, Sarah E. Church, Cem Meydan, George Church, Afshin Beheshti, Jaime Mateus, Christopher E. Mason
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Spaceflight can change metabolic, immunological, and biological homeostasis and cause skin rashes and irritation, yet the molecular basis remains unclear. To investigate the impact of short-duration spaceflight on the skin, we conducted skin
Externí odkaz:
https://doaj.org/article/60b54f6af6b24c2694a1e6a88a4f7b8d
Autor:
Timothy J. Doyle, Megan Gumke, Danielle Stanek, Joshua Moore, Brian Buck, Timothy Locksmith, Kelly Tomson, Sarah Schmedes, George Churchwell, Shan Justin Hubsmith, Baskar Krishnamoorthy, Karalee Poschman, Brandi Danforth, Daniel Chacreton
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 4, Pp 634-643 (2024)
In 2022, concurrent outbreaks of hepatitis A, invasive meningococcal disease (IMD), and mpox were identified in Florida, USA, primarily among men who have sex with men. The hepatitis A outbreak (153 cases) was associated with hepatitis A virus genoty
Externí odkaz:
https://doaj.org/article/e5b637d4100a45fc97e21ba33ca4d025
Publikováno v:
Proceedings of International Symposium on Grids and Clouds (ISGC) 2017 — PoS(ISGC2017).
In this paper, we report the development of fanless single rack data centre (SRDC) which is noise-free and of efficiency in power, energy and operation. SRDC could be deployed as a building block according to different needs and close to users to red
Autor:
Yingtai Chen, Jianhua Yin, Lulu Zhao, Guangyu Zhou, Shichen Dong, Yueming Zhang, Penghui Niu, Hu Ren, Tianjiao Zheng, Juan Yan, Wenbin Li, Peiqin Ma, Cuijuan Zhang, Chen Wei, George Church, Guibo Li, Dongbing Zhao
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background Little is known on the tumor microenvironment (TME) response after neoadjuvant chemotherapy (NACT) in gastric cancer on the molecular level. Methods Here, we profiled 33,589 cell transcriptomes in 14 samples from 11 gastric cancer
Externí odkaz:
https://doaj.org/article/09d994aad5fc43f7b1b60b2e044ce359
Autor:
Fang, Fei1, Liu, George Chu1, Zhou, Xiaohua1, Yang, Stuart2, Reich, Heather Naomi2, Williams, Vanessa1, Hu, Amanda1, Pan, Janice1, Konvalinka, Ana1, Oudit, Gavin Yadram3, Scholey, James William1,2, John, Rohan4 rohan.john@uhn.on.ca
Publikováno v:
PLoS ONE. Aug2013, Vol. 8 Issue 8, p1-17. 17p.
Autor:
Yuting Chen, Eriona Hysolli, Anlu Chen, Stephen Casper, Songlei Liu, Kevin Yang, Chenli Liu, George Church
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Whole-genome recoding has been shown to enable nonstandard amino acids, biocontainment and viral resistance in bacteria. Here the authors extend this to human cells using base editing to convert TAG to TAA for 33 essential genes via a single transfec
Externí odkaz:
https://doaj.org/article/4d4f5949126f4732aa4cc9b34be9ee16
Autor:
Nicholas F G Chen, Chrispin Chaguza, Luc Gagne, Matthew Doucette, Sandra Smole, Erika Buzby, Joshua Hall, Stephanie Ash, Rachel Harrington, Seana Cofsky, Selina Clancy, Curtis J Kapsak, Joel Sevinsky, Kevin Libuit, Daniel J Park, Peera Hemarajata, Jacob M Garrigues, Nicole M Green, Sean Sierra-Patev, Kristin Carpenter-Azevedo, Richard C Huard, Claire Pearson, Kutluhan Incekara, Christina Nishimura, Jian Ping Huang, Emily Gagnon, Ethan Reever, Jafar Razeq, Anthony Muyombwe, Vítor Borges, Rita Ferreira, Daniel Sobral, Silvia Duarte, Daniela Santos, Luís Vieira, João Paulo Gomes, Carly Aquino, Isabella M Savino, Karinda Felton, Moneeb Bajwa, Nyjil Hayward, Holly Miller, Allison Naumann, Ria Allman, Neel Greer, Amary Fall, Heba H Mostafa, Martin P McHugh, Daniel M Maloney, Rebecca Dewar, Juliet Kenicer, Abby Parker, Katharine Mathers, Jonathan Wild, Seb Cotton, Kate E Templeton, George Churchwell, Philip A Lee, Maria Pedrosa, Brenna McGruder, Sarah Schmedes, Matthew R Plumb, Xiong Wang, Regina Bones Barcellos, Fernanda M S Godinho, Richard Steiner Salvato, Aimee Ceniseros, Mallery I Breban, Nathan D Grubaugh, Glen R Gallagher, Chantal B F Vogels
Publikováno v:
PLoS Biology, Vol 21, Iss 6, p e3002151 (2023)
The 2022 multicountry mpox outbreak concurrent with the ongoing Coronavirus Disease 2019 (COVID-19) pandemic further highlighted the need for genomic surveillance and rapid pathogen whole-genome sequencing. While metagenomic sequencing approaches hav
Externí odkaz:
https://doaj.org/article/f6624948d6784e6da2c1bd198855dab0