Zobrazeno 1 - 10
of 50
pro vyhledávání: '"George Carlson"'
Autor:
Taek-Kyun Kim, Inyoul Lee, Ji-Hoon Cho, Brenda Canine, Andrew Keller, Nathan D. Price, Daehee Hwang, George Carlson, Leroy Hood
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-14 (2020)
Abstract Complex diseases involve dynamic perturbations of pathophysiological processes during disease progression. Transcriptional programs underlying such perturbations are unknown in many diseases. Here, we present core transcriptional regulatory
Externí odkaz:
https://doaj.org/article/0ccc6d1799fa414ea34bbc6cb5e976f9
Autor:
Carl George Carlson
Publikováno v:
Muscles. 1:75-81
A recent study describing unique effects of myostatin inhibition on a severely dystrophic (mdx) muscle, and independent experiments showing that branched fibers are uniquely sensitive to activity-induced membrane rupture, have led to a new hypothesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51f2c2e074c0bbc131e604b41f731868
https://doi.org/10.3390/muscles1010008
https://doi.org/10.3390/muscles1010008
Autor:
Linda H. Younkin, Josef Anrather, Rose Pistik, George Carlson, Michelle Murphy, Lidia Garcia-Bonilla, Steven Younkin, Laibaik Park, Costantino Iadecola, Kenzo Koizumi, Ping Zhou, Ken Uekawa
Publikováno v:
Circulation Research. 121:258-269
Rationale: Increasing evidence indicates that alterations of the cerebral microcirculation may play a role in Alzheimer disease, the leading cause of late-life dementia. The amyloid-β peptide (Aβ), a key pathogenic factor in Alzheimer disease, indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a325783b1cbd45036e7eb172a3f53d27
https://doi.org/10.1161/circresaha.117.311054
https://doi.org/10.1161/circresaha.117.311054
Autor:
Christopher Borowy, Ravi Kumar, C. George Carlson, Cory Nielsen, Kimberly Jacinto, Ross M. Potter
Publikováno v:
Journal of Cellular Physiology. 232:1774-1793
The efficacy of two ActRIIB ligand-trapping agents (RAP-031 and RAP-435) in treating muscular dystrophy was examined by determining their morphological effects on the severely dystrophic triangularis sterni (TS) muscle of the mdx mouse, a model for D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2251f5b1f853864bfba4862f75497047
https://doi.org/10.1002/jcp.25694
https://doi.org/10.1002/jcp.25694
Publikováno v:
Muscle & Nerve. 53:431-437
Introduction Previous experiments have indicated that in vivo administration of ursodeoxycholic acid (UDCA) inhibits nuclear NF-κB activation and has beneficial effects on the structure and function of dystrophic (mdx) muscle. We examined the effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::957869a71319862c9dfa288b46cbd9e4
https://doi.org/10.1002/mus.24755
https://doi.org/10.1002/mus.24755
Publikováno v:
Journal of Cellular Physiology. 231:788-797
Inhibiting the NF-κB signaling pathway provides morphological and functional benefits for the mdx mouse, a model for Duchenne muscular dystrophy characterized by chronic elevations in the nuclear expression of p65, the transactivating component of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e79e267d15e6319a28ea8b1a3aef225
https://doi.org/10.1002/jcp.25085
https://doi.org/10.1002/jcp.25085
Autor:
Eleanor K, Pickett, Christopher M, Henstridge, Elizabeth, Allison, Rose, Pitstick, Amy, Pooler, Susanne, Wegmann, George, Carlson, Bradley T, Hyman, Tara L, Spires-Jones
Publikováno v:
Synapse (New York, N.y.)
Synaptic dysfunction and loss is the strongest pathological correlate of cognitive decline in Alzheimer's disease (AD) with increasing evidence implicating neuropathological tau protein in this process. Despite the knowledge that tau spreads through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cd7e5fe675ebcc98897eb3033cce8f70
https://pubmed.ncbi.nlm.nih.gov/28196395
https://pubmed.ncbi.nlm.nih.gov/28196395
Autor:
Cory, Nielsen, Ross M, Potter, Christopher, Borowy, Kimberly, Jacinto, Ravi, Kumar, C George, Carlson
Publikováno v:
Journal of cellular physiology. 232(7)
The efficacy of two ActRIIB ligand-trapping agents (RAP-031 and RAP-435) in treating muscular dystrophy was examined by determining their morphological effects on the severely dystrophic triangularis sterni (TS) muscle of the mdx mouse, a model for D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c4c5a37838e98954f3068e3658e10ac6
https://pubmed.ncbi.nlm.nih.gov/27859236
https://pubmed.ncbi.nlm.nih.gov/27859236
Autor:
Cathy Bledsoe, Jonas Berge, W. Tyler Winders, C. George Carlson, Eric Turin, Ashley Siegel, Beniamino Palmeiri, Gregory Millman, Jesse Lavin, John Rutter, Francesca Gatti
Publikováno v:
Neuromuscular Disorders. 19:131-139
The whole body tension (WBT) method was used to evaluate the hypothesis that long term treatment with NF-kappaB inhibitors improves the total forward pulling tension exerted by the limb musculature of the mdx mouse. Mdx mice exhibited significantly r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2631a3a18e3a616f52fbdd17d36707b6
https://doi.org/10.1016/j.nmd.2008.10.006
https://doi.org/10.1016/j.nmd.2008.10.006