Zobrazeno 1 - 10
of 85
pro vyhledávání: '"George C. Wellman"'
Autor:
Hannah R. Ferris, Nathan C. Stine, David C. Hill-Eubanks, Mark T. Nelson, George C. Wellman, Masayo Koide
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16284 (2023)
Functional hyperemia—activity-dependent increases in local blood perfusion—underlies the on-demand delivery of blood to regions of enhanced neuronal activity, a process that is crucial for brain health. Importantly, functional hyperemia deficits
Externí odkaz:
https://doaj.org/article/7d9b56705de84971b27290e7788825cf
Autor:
Nuria Villalba, George C. Wellman
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/853a75594243425c9d87ac62382d5321
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Subarachnoid hemorrhage (SAH) is a common form of hemorrhagic stroke associated with high rates of mortality and severe disability. SAH patients often develop severe neurological deficits days after ictus, events attributed to a phenomenon referred t
Externí odkaz:
https://doaj.org/article/61271d7e0a5d4b2d97e27f79b490bde3
Publikováno v:
Stroke Research and Treatment, Vol 2013 (2013)
Aneurysmal subarachnoid hemorrhage (SAH) has devastating consequences on brain function including profound effects on communication between neurons and the vasculature leading to cerebral ischemia. Physiologically, neurovascular coupling represents a
Externí odkaz:
https://doaj.org/article/4da2e0fd10c14ac3a88482b8963ee782
Autor:
Masayo Koide, Hannah R. Ferris, George C. Wellman, Mark T. Nelson, Thomas A Longden, David C. Hill-Eubanks, Osama F. Harraz, Fabrice Dabertrand, Adam Greenstein
Publikováno v:
J Clin Invest
Dementia resulting from small vessel diseases of the brain (SVDs) is an emerging epidemic for which there is no treatment. Hypertension is the major risk factor for SVDs, but how hypertension damages the brain microcirculation is unclear. Here, we sh
Autor:
Li Yang, Lei Zhou, Fei Wang, Heng-Jui Chang, Ming-Ying Luo, Giuseppe Lanzino, George C. Wellman
Publikováno v:
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 16(2)
Endocrine dysfunction is known to occur after traumatic brain injury. The purpose of this study was to examine the incidence of various endocrine dysfunctions after a stroke. The Taiwan National Health Insurance Research Database (NHIRD) was searched
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 37:3625-3634
Subarachnoid hemorrhage (SAH) induces acute changes in the cerebral microcirculation. Recent findings ex vivo suggest neurovascular coupling (NVC), the process that increases cerebral blood flow upon neuronal activity, is also impaired after SAH. The
Publikováno v:
The FASEB Journal. 33
Publikováno v:
Frontiers in Physiology
Voltage-dependent calcium channels (VDCCs) play an essential role in regulating cerebral artery diameter and it is widely appreciated that the L-type VDCC, CaV1.2, encoded by the CACNA1C gene, is a principal Ca2+ entry pathway in vascular myocytes. H
Publikováno v:
Journal of Molecular Neuroscience. 54:443-450
Pituitary adenylate cyclase activating polypeptide (PACAP) is a potent vasodilator of numerous vascular beds, including cerebral arteries. Although PACAP-induced cerebral artery dilation is suggested to be cyclic AMP (cAMP)-dependent, the downstream