Zobrazeno 1 - 10
of 14
pro vyhledávání: '"George C. Shaw"'
Autor:
Mehrdad Golian, MD, F. Daniel Ramirez, MD, MSc, Wael Alqarawi, MD, Simon P. Hansom, MBBS, Pablo B. Nery, MD, Calum J. Redpath, MBChB, PhD, Girish M. Nair, MBBS, MSc, FHRS, George C. Shaw, MD, FHRS, Darryl R. Davis, MD, David H. Birnie, MBChB, MD, Mouhannad M. Sadek, MD, FHRS
Publikováno v:
Heart Rhythm O2, Vol 1, Iss 5, Pp 317-323 (2020)
Background: High-power short-duration (HPSD) ablation has been explored for pulmonary vein isolation. Early data suggest similar efficacy with shorter procedure times and perhaps greater safety. Data are lacking on the use of this ablation strategy f
Externí odkaz:
https://doaj.org/article/a8d76179f8ac45f99cf8273f4f2f8759
Autor:
Mouhannad M. Sadek, Mehrdad Golian, Calum J. Redpath, Wael Alqarawi, F. Daniel Ramirez, Girish M. Nair, Pablo B. Nery, Simon P. Hansom, George C. Shaw, Darryl R. Davis, David H. Birnie
Publikováno v:
Heart Rhythm O2
Heart Rhythm O2, Vol 1, Iss 5, Pp 317-323 (2020)
Heart Rhythm O2, Vol 1, Iss 5, Pp 317-323 (2020)
Background High-power short-duration (HPSD) ablation has been explored for pulmonary vein isolation. Early data suggest similar efficacy with shorter procedure times and perhaps greater safety. Data are lacking on the use of this ablation strategy fo
Autor:
Leonard I. Zon, Owen J. Tamplin, Paul F. McBride, Kelli J. Carroll, Dhvanit I. Shah, Diana S. Branco, Ebrahim Shafizadeh, Gordon J. Hildick-Smith, Heidi Anderson, Clara Wong, Trista E. North, Barry H. Paw, Jeffrey D. Cooney, Patrick G. Gallagher, Arthur J. Dalton, George C. Shaw
Publikováno v:
Developmental Biology. 373:431-441
Growth Factor Independence (Gfi) transcription factors play essential roles in hematopoiesis, differentially activating and repressing transcriptional programs required for hematopoietic stem/progenitor cell (HSPC) development and lineage specificati
Autor:
Nathan Vandergrift, Barton F. Haynes, Kwan-Ki Hwang, Eleanor Marshal, S. Munir Alam, David C. Montefiori, David M. Margolis, Supriya Munshaw, Hua-Xin Liao, Michael Egholm, Ruijun Zhang, Katharine J. Bar, Bozena Hanczaruk, Sonya L. Heath, Thomas N. Denny, Jae-Sung Yu, Scott D. Boyd, George C. Shaw, Birgitte B. Simen, Garnett Kelsoe, Thomas B. Kepler, Xiaozhi Lu, Georgia D. Tomaras, Paul A. Goepfert, John F. Whitesides, Feng Gao, Martin Markowitz, Dawn J. Marshall, Gerald Voss, Andrew Fire, Xi Chen, M. Anthony Moody
Publikováno v:
The Journal of Experimental Medicine
Many HIV-1 envelope-reactive antibodies shortly after HIV-1 transmission may arise from crow-reactive memory B cells previously stimulated by non-HIV-1 host or microbial antigens
The initial antibody response to HIV-1 is targeted to envelope (En
The initial antibody response to HIV-1 is targeted to envelope (En
Autor:
Joseph R. Bloomer, Guang Yang, Jerry Kaplan, Nathaniel B. Langer, Barry H. Paw, George C. Shaw, Liangtao Li, Yongming Wang
Publikováno v:
Experimental Hematology. 39:784-794
Objective Most patients with erythropoietic protoporphyria have deficient ferrochelatase (FECH) activity due to changes in FECH DNA. We evaluated seven patients with erythropoietic protoporphyria phenotype in whom abnormalities of FECH DNA were not f
Autor:
Barry H. Paw, Kimberly Dooley, Jennifer L. Axe, Bruce A. Barut, Heidi L. Schubert, Alan J. Davidson, Paula G. Fraenkel, Jenna L. Galloway, Rebecca A. Wingert, Paul D. Kingsley, Jerry Kaplan, Opal S. Chen, George C. Shaw, James Palis, Bettina Schmidt, Leonard I. Zon, Gerhard J. Weber, Helen Foott
Publikováno v:
Nature. 436:1035-1039
Iron is required to produce haem and iron–sulphur (Fe–S) clusters, processes thought to occur independently1,2. Here we show that the hypochromic anaemia in shiraz (sir) zebrafish mutants is caused by deficiency of glutaredoxin 5 (grx5), a gene r
Autor:
Sumon Datta, Luanne L. Peters, Kathryn M. Deck, Jerry Kaplan, Michael J. Chen, George C. Shaw, Amy J. Lambert, Nicholas C. Huston, Sheila A. Anderson, Matthias W. Hentze, Zong Wei, Nathaniel B. Langer, Babette Gwynn, Liangtao Li, Richard S. Eisenstein, Kenneth E. Sahr, Jacky Chung, Bruno Galy, Wen Chen, Diane M. Ward, Wange Lu, Barry H. Paw, Prasad N. Paradkar, Thorsten M. Schlaeger, Leah F. Boyer, Johannes G. Wittig
Mitochondrial iron is essential for the biosynthesis of heme and iron-sulfur ([Fe-S]) clusters in mammalian cells. In developing erythrocytes, iron is imported into the mitochondria by MFRN1 (mitoferrin-1, SLC25A37). Although loss of MFRN1 in zebrafi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a03f726b818204f4ff0573df0704e4df
https://europepmc.org/articles/PMC3953295/
https://europepmc.org/articles/PMC3953295/
Autor:
Karl Hsu, Ebrahim Shafizadeh, Tyler B. Moran, Barry H. Paw, Jeffrey D. Cooney, John P. Kanki, Robert I. Handin, Gabriele E. Ackermann, Nathaniel B. Langer, George C. Shaw, David Traver, Yi Zhou, Bruce A. Barut, Wyatt Horsely, Hui Feng Lin, Dongdong Ma, Nikolaus S. Trede, Dhvanit I. Shah, Sarah A. Wojiski, George Kourkoulis, Alan B. Cantor, Julio D. Amigo, Alan J. Davidson, Ming Yu, John J. Cope
Publikováno v:
Blood. 114(21)
The nuclear protein FOG-1 binds transcription factor GATA-1 to facilitate erythroid and megakaryocytic maturation. However, little is known about the function of FOG-1 during myeloid and lymphoid development or how FOG-1 expression is regulated in an
Autor:
Babette Gwynn, Jerry Kaplan, Adriana Donovan, John J. Cope, Gabriele E. Ackermann, George C. Shaw, Alison Brownlie, Bruce A. Barut, Rena Balzan, Mitchell J. Weiss, Barry H. Paw, Liangtao Li, Rebecca A. Wingert, Kenneth Corson, Candace Hersey, Emmanuel Minet, David Traver, Nikolaus S. Trede, Yi Zhou, Amy J. Lambert, Luanne L. Peters, Leonard I. Zon
Publikováno v:
Nature. 440(7080)
Iron has a fundamental role in many metabolic processes, including electron transport, deoxyribonucleotide synthesis, oxygen transport and many essential redox reactions involving haemoproteins and Fe-S cluster proteins. Defective iron homeostasis re
Autor:
Joseph R. Bloomer, Nathaniel B. Langer, Liangtao Li, Barry H. Paw, Jerry Kaplan, George C. Shaw, Yongming Wang
Publikováno v:
Blood. 108:3-3
Mitoferrin (mfrn, slc25a37) is the high-affinity transporter of iron into mitochondria of developing erythroblasts and is essential for normal erythropoiesis. Recently, we described the cloning and characterization of mfrn in the zebrafish frascati (