Zobrazeno 1 - 10
of 17
pro vyhledávání: '"George C. Brittain"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-5 (2021)
Externí odkaz:
https://doaj.org/article/23b227cfc3f94b7c8bd7efbdb64f1461
Autor:
Sergei Gulnik, George C. Brittain
Publikováno v:
Cytometry Part A. 91:351-363
A biochemical system and method have been developed to enable the quantitative measurement of cytoplasmic versus nuclear localization within cells in whole blood. Compared with the analyses of nuclear localization by western blot or fluorescence micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd745294f78d95f36678bd3417c5bc03
https://doi.org/10.1002/cyto.a.23103
https://doi.org/10.1002/cyto.a.23103
Autor:
George C. Brittain, Tyler Milston Renner, Yong Q. Chen, Vera A. Tang, Edgar Martinez, Marc-André Langlois, Sergei Gulnik
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
The CytoFLEX is a novel semiconductor-based flow cytometer that utilizes avalanche photodiodes, wavelength-division multiplexing, enhanced optics, and diode lasers to maximize light capture and minimize optical and electronic noise. Due to an increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d779c4000f973d4a0dc75f47b3803ecf
http://europepmc.org/articles/PMC6831566
http://europepmc.org/articles/PMC6831566
Autor:
Anna K. Fritzsche, Tyler Milston Renner, Vera A. Tang, Jennifer Jones, Dylan Burger, Edwin van der Pol, Marc-André Langlois, George C. Brittain, Joshua A. Welsh, Joanne Lannigan
There has been renewed interest in the use of flow cytometry for single particle phenotypic analysis of particles in the nanometer size-range such as viruses, organelles, bacteria and extracellular vesicles (EVs). However, many of these particles are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0a49d6eee4078c6392dceb0caa92cd1
https://doi.org/10.1101/614461
https://doi.org/10.1101/614461
Autor:
Khushroo Gandhi, Xiaochun Chen, James C. Sturm, Curt I. Civin, MinJung Kim, George C. Brittain, Sergei Gulnik, Zendra Peilun Lee, Tony Ward, Alison Skelley, Yu Chen, Lee Aurich, Joseph D'Silva, Robert H. Austin, Christopher Dosier, Diether J. Recktenwald, James R. Moynihan
Publikováno v:
Cytometry Part A. 89:1073-1083
We previously developed a Deterministic Lateral Displacement (DLD) microfluidic method in silicon to separate cells of various sizes from blood (Davis et al., Proc Natl Acad Sci 2006;103:14779-14784; Huang et al., Science 2004;304:987-990). Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfb0794eb59b1368e0b3abb001f4bdc4
https://doi.org/10.1002/cyto.a.23019
https://doi.org/10.1002/cyto.a.23019
Publikováno v:
Molecular Neurobiology
The tumor necrosis factor receptor-associated factors (TRAFs) have been classically described as adaptor proteins that function as solely cytosolic signaling intermediates for the TNF receptor superfamily, Toll-like receptors (TLRs), NOD, like recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a36f2b34ee1419a0983e14d65b0696ed
https://doi.org/10.1007/s12035-016-9742-4
https://doi.org/10.1007/s12035-016-9742-4
Autor:
Jiayi Yu, Robyn Starr, Hongbo Hu, Shao Cong Sun, George C. Brittain, Xuhong Cheng, Yichuan Xiao, Jin Jin, Mikyoung Chang, Jae Hoon Chang
Publikováno v:
Nature Immunology. 21:1134-1134
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3216cbe32df803079d38a2f72c1eb63
https://doi.org/10.1038/s41590-020-0748-8
https://doi.org/10.1038/s41590-020-0748-8
Autor:
Yichuan Xiao, Xuhong Cheng, Jin Jin, Mako Nakaya, Qiang Zou, Shao Cong Sun, Hongbo Hu, Xiaofei Zhou, George C. Brittain, Mikyoung Chang
Publikováno v:
The Journal of Experimental Medicine
TPL2 is required for Th17-mediated neuroinflammation during EAE by regulating the TAK1 signaling axis downstream of the IL-17R in astrocytes.
Development of autoimmune diseases, such as multiple sclerosis and experimental autoimmune encephalomye
Development of autoimmune diseases, such as multiple sclerosis and experimental autoimmune encephalomye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb84cda676abb3c500b010fc9351eb2d
https://doi.org/10.1084/jem.20132640
https://doi.org/10.1084/jem.20132640
Autor:
Shao Cong Sun, Hongbo Hu, Jiayi Yu, George C. Brittain, Qiang Zou, Stephanie S. Watowich, Frédérick A. Mallette, Haiyan S. Li, Jin Jin, Yichuan Xiao, Xuhong Cheng
Publikováno v:
Immunity. 40(3):342-354
SummaryProduction of type I interferons (IFN-I) is a crucial innate immune mechanism against viral infections. IFN-I induction is subject to negative regulation by both viral and cellular factors, but the underlying mechanism remains unclear. We repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::138b16abf2390b1e6b7b00c09e083de1
Autor:
Xiaodong Wang, Robert Brink, Christine Stansberg, Xiaofei Zhou, Shao Cong Sun, Jin Jin, Hongbo Hu, Jae Hoon Chang, Øivind Torkildsen, Xuhong Cheng, Yichuan Xiao, George C. Brittain, Mikyoung Chang
Publikováno v:
Nature medicine
Microglia are crucial for the pathogenesis of multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis (EAE). Here we show that the E3 ubiquitin ligase Peli1 is abundantly expressed in microglia and promotes microglial activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f882a694d27f6d2a60b70486a95bf93d
https://doi.org/10.1038/nm.3111
https://doi.org/10.1038/nm.3111