Safety of growth hormone replacement in survivors of cancer and intracranial and pituitary tumours: a consensus statement

Autor: Margaret C S Boguszewski, Cesar L Boguszewski, Wassim Chemaitilly, Laurie E Cohen, Judith Gebauer, Claire Higham, Andrew R Hoffman, Michel Polak, Kevin C J Yuen, Nathalie Alos, Zoltan Antal, Martin Bidlingmaier, Beverley M K Biller, George Brabant, Catherine S Y Choong, Stefano Cianfarani, Peter E Clayton, Regis Coutant, Adriane A Cardoso-Demartini, Alberto Fernandez, Adda Grimberg, Kolbeinn Guðmundsson, Jaime Guevara-Aguirre, Ken K Y Ho, Reiko Horikawa, Andrea M Isidori, Jens Otto Lunde Jørgensen, Peter Kamenicky, Niki Karavitaki, John J Kopchick, Maya Lodish, Xiaoping Luo, Ann I McCormack, Lillian Meacham, Shlomo Melmed, Sogol Mostoufi Moab, Hermann L Müller, Sebastian J C M M Neggers, Manoel H Aguiar Oliveira, Keiichi Ozono, Patricia A Pennisi, Vera Popovic, Sally Radovick, Lars Savendahl, Philippe Touraine, Hanneke M van Santen, Gudmundur Johannsson

Publikováno v: European Journal of Endocrinology, 186(6), 35-52. Bioscientifica Ltd
Boguszewski, M C S, Boguszewski, C L, Chemaililly, W, Cohen, L E, Gebauer, J, Higham, C, Hoffman, A R, Polak, M, Yuen, K C J, Alos, N, Antal, Z, Bidlingmaier, M, Biller, B M K, Brabant, G, Choong, C S Y, Cianfarani, S, Clayton, P E, Coutant, R, Cardoso-Demartini, A A, Fernandez, A, Grimberg, A, Guðmundsson, K, Guevara-Aquirre, J, Ho, K K Y, Horikawa, R, Isidori, A M, Jørgensen, J O L, Kamenicky, P, Karavitaki, N, Kopchick, J J, Lodish, M, Luo, X, McCormack, A I, Meacham, L, Melmed, S, Mostoufi Moab, S, Müller, H L, Neggers, S J C M M, Aguiar Oliveira, M H, Ozono, K, Pennisi, P A, Popovic, V, Radovick, S, Savendahl, L, Touraine, P, van Santen, H H & Johannsson, G 2022, ' Safety of growth hormone replacement in survivors of cancer and intracranial and pituitary tumours : a consensus statement ', European Journal of Endocrinology, vol. 186, no. 6, pp. P35-P52 . https://doi.org/10.1530/EJE-21-1186

Growth hormone (GH) has been used for over 35 years, and its safety and efficacy has been studied extensively. Experimental studies showing the permissive role of GH/insulin-like growth factor 1 (IGF-I) in carcinogenesis have raised concerns regardin

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https://hdl.handle.net/2108/313619