Zobrazeno 1 - 8
of 8
pro vyhledávání: '"George Bowley"'
Autor:
George Bowley, Sophie Irving, Imo Hoefer, Robert Wilkinson, Gerard Pasterkamp, Hazem M. S. Darwish, Stephen White, Sheila E. Francis, Tim Chico, Emily Noel, Jovana Serbanovic-Canic, Paul C. Evans
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Local haemodynamics control arterial homeostasis and dysfunction by generating wall shear stress (WSS) which regulates endothelial cell (EC) physiology. Here we use a zebrafish model to identify genes that regulate EC proliferation in respon
Externí odkaz:
https://doaj.org/article/0c4300ace1ce4f219ddb975cc9ed40fe
Autor:
Elisabeth Kugler, Ryan Snodgrass, George Bowley, Karen Plant, Jovana Serbanovic-Canic, Noémie Hamilton, Paul C Evans, Timothy Chico, Paul Armitage
Publikováno v:
Vascular Biology, Vol 3, Iss 1, Pp 1-16 (2021)
The role of blood flow in vascular development is complex and context-dependent. In this study, we quantify the effect of the lack of blood flow on embryonic vascular development on two vascular beds, namely the cerebral and trunk vasculature in zebr
Externí odkaz:
https://doaj.org/article/5accb5ba9bbe4e05ba735c616f0f73e1
Publikováno v:
F1000Research, Vol 10 (2021)
Introduction: Endothelial cell (EC) proliferation is a fundamental determinant of vascular development and homeostasis, and contributes to cardiovascular disease by increasing vascular permeability to blood-borne lipoproteins. Rodents have been tradi
Externí odkaz:
https://doaj.org/article/e9b50c2afb394a04a60954219b401992
Autor:
Allan Lawrie, Elizabeth Kugler, George Bowley, Emily S. Noël, Jovana Serbanovic-Canic, Freek van Eeden, Timothy J. A. Chico, Paul C. Evans, Robert N. Wilkinson
Publikováno v:
British Journal of Pharmacology. 179:900-917
Mammalian models including non-human primates, pigs and rodents have been used extensively to study the mechanisms of cardiovascular disease. However, there is an increasing desire for alternative model systems that provide excellent scientific value
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d17d1b77d2aacc67fd0c167f36c521
https://doi.org/10.1111/bph.15473
https://doi.org/10.1111/bph.15473
Autor:
Paul A. Armitage, George Bowley, Jovana Serbanovic-Canic, Ryan Snodgrass, Elisabeth Kugler, Karen Plant, Noémie Hamilton, Timothy J. A. Chico, Paul C. Evans
Publikováno v:
Vascular Biology
Vascular Biology, Vol 3, Iss 1, Pp 1-16 (2021)
Vascular Biology, Vol 3, Iss 1, Pp 1-16 (2021)
The role of blood flow in vascular development is complex and context-dependent. In this study, we quantify the effect of the lack of blood flow on embryonic vascular development on two vascular beds, namely the cerebral and trunk vasculature in zebr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1371760b108bc97f71c7d7f6eb48cccb
Publikováno v:
Basic science.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5ba3605255358114a4446ac817cf044
https://doi.org/10.1136/heartjnl-2021-bcs.213
https://doi.org/10.1136/heartjnl-2021-bcs.213
Autor:
Timothy J. A. Chico, George Bowley, Paul C. Evans, Karen Plant, Elisabeth Kugler, Paul A. Armitage, Jovana Serbanovic-Canic, Ryan Snodgrass
The role of blood flow is complex and context-dependent. In this study, we quantify the effect of the lack of blood flow on vascular development and compare its impact in two vascular beds, namely the cerebral and trunk vasculature, using zebrafish a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::005f6238c306c8211d87c21811f9487a
https://doi.org/10.1101/2020.07.23.216192
https://doi.org/10.1101/2020.07.23.216192
Publikováno v:
F1000Research. 10:1032
Introduction: Endothelial cell (EC) proliferation is a fundamental determinant of vascular development and homeostasis, and contributes to cardiovascular disease by increasing vascular permeability to blood-borne lipoproteins. Rodents have been tradi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b5cdcf5b334d399333e40246ae4ed47
https://doi.org/10.12688/f1000research.73130.1
https://doi.org/10.12688/f1000research.73130.1