Zobrazeno 1 - 10
of 23
pro vyhledávání: '"George Borg"'
Autor:
George Borg
Publikováno v:
George Borg
The “Instrumental Revolution” in chemistry refers to a transitional period in the mid-20th century during which sophisticated instrumentation based on physical principles was introduced to solve chemical problems. Historical and philosophical ref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f77ada05934928e7a1911916a72462
https://doi.org/10.1016/j.shpsa.2019.05.008
https://doi.org/10.1016/j.shpsa.2019.05.008
Autor:
George Borg
Publikováno v:
Perspectives on Science. 27:861-890
An important fact about human labor is that it can result not just in reproduction of what it started with, but in something new, a surplus product. When the latter is a means of production, it makes possible a mechanism of change consisting of repro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b02e228b6e8031bbefc7c5315a67e57
https://doi.org/10.1162/posc_a_00328
https://doi.org/10.1162/posc_a_00328
Autor:
George Borg
Publikováno v:
Philosophia. 48:421-423
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::550d761e19637f392b94044740d6cf6a
https://doi.org/10.1007/s11406-019-00100-9
https://doi.org/10.1007/s11406-019-00100-9
Autor:
Virginia Berry, Alexander M. Long, Tom DeMelfi, Nicholas Doerr, Philip Roveto, Yohannes Teffera, Loren Berry, Anthony Polverino, Danlin Chen, Juan Estrada, George Borg, Roger Zanon, Charlie Starnes, James Bready, Shawn Harriman, Kelly Regal, Michael Schrag, Jean-Christophe Harmange, David Bauer, Russell Graceffa, Daniel S. La, Vinod F. Patel, Sesha Neervannan, Matthew Weiss, Angela Coxon, Andrew Tasker, Douglas A. Whittington, Michele Potashman, Julie Flynn, Stephen Kaufman, Deborah Choquette
Publikováno v:
Journal of Medicinal Chemistry. 51:1668-1680
We have previously shown N-arylnaphthamides can be potent inhibitors of vascular endothelial growth factor receptors (VEGFRs). N-Alkyl and N-unsubstituted naphthamides were prepared and found to yield nanomolar inhibitors of VEGFR-2 (KDR) with an imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16dcee1e3d9e10f0342608292540a2cd
https://doi.org/10.1021/jm701098w
https://doi.org/10.1021/jm701098w
Publikováno v:
Angewandte Chemie International Edition. 41:3188-3191
Asaresultoftheir transient nature, the utilityof these compounds inorganicchemistryremainslimited. Theisolation of tetrahe-dralintermediatescouldprovideinsightintotheacyl-transferprocess as well as useful compounds for organic synthesis.Whiletheadduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::540107e510f408709340c8de38bdc9c8
https://doi.org/10.1002/1521-3773(20020902)41:17<3188::aid-anie3188>3.0.co
https://doi.org/10.1002/1521-3773(20020902)41:17<3188::aid-anie3188>3.0.co
Publikováno v:
Tetrahedron Letters. 40:6709-6712
A one-pot method for the asymmetric synthesis of tert -butanesulfinyl-protected amines is described. The ketones bd2 are condensed with (R)-tert -butanesulfinamide bd1 and the tert -butanesulfinyl imine intermediates reduced in situ with NaBH 4 to af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6927b9b38f204bb7a64f4ce05b222ecb
https://doi.org/10.1016/s0040-4039(99)01351-9
https://doi.org/10.1016/s0040-4039(99)01351-9
Autor:
David Marcoux, Pascal Bindschädler, David A. Evans, George Borg, Joseph E. Pero, Anna Chiu, Alexander W. H. Speed
Publikováno v:
Organic letters. 13(14)
The use of cyclic α,β-unsaturated iminium-ion dienophiles is documented in two highly diastereoselective Diels–Alder (DA) reactions. The dienophilic counterion was found to have a significant effect on reactivity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d1e2ed282bd69fcda44197b2d50a56c
https://pubmed.ncbi.nlm.nih.gov/21678927
https://pubmed.ncbi.nlm.nih.gov/21678927
Publikováno v:
Tetrahedron Letters. 42:1433-1435
A method for the asymmetric synthesis of pre-protected α,α-disubstituted amino acids is described. 5-Methylfuryllithium is added into sulfinyl ketimines 1 in the presence of AlMe3 to afford the sulfinamides 2 in 75–97% yields and with diastereose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a7cb3de8a477f1cb288134352d7eb16
https://doi.org/10.1016/s0040-4039(00)02300-5
https://doi.org/10.1016/s0040-4039(00)02300-5
Publikováno v:
ChemInform. 30
A one-pot method for the asymmetric synthesis of tert -butanesulfinyl-protected amines is described. The ketones bd2 are condensed with (R)-tert -butanesulfinamide bd1 and the tert -butanesulfinyl imine intermediates reduced in situ with NaBH 4 to af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9ee4b9d5354f7b4510d3fa97503e05b
https://doi.org/10.1002/chin.199947045
https://doi.org/10.1002/chin.199947045
Publikováno v:
ChemInform. 32
A method for the asymmetric synthesis of pre-protected α,α-disubstituted amino acids is described. 5-Methylfuryllithium is added into sulfinyl ketimines 1 in the presence of AlMe3 to afford the sulfinamides 2 in 75–97% yields and with diastereose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94cdbe235ced48a5cac880f9c66339e5
https://doi.org/10.1002/chin.200121172
https://doi.org/10.1002/chin.200121172