Zobrazeno 1 - 10
of 101
pro vyhledávání: '"George Banting"'
Publikováno v:
Biology Open, Vol 2, Iss 11, Pp 1253-1263 (2013)
Summary The integral membrane protein CD317/tetherin has been associated with a plethora of biological processes, including restriction of enveloped virus release, regulation of B cell growth, and organisation of membrane microdomains. CD317 possesse
Externí odkaz:
https://doaj.org/article/f99f0174fac345f99bbc53e929c457b9
Publikováno v:
eLife, Vol 5 (2016)
Exosomes are extracellular vesicles that are released when endosomes fuse with the plasma membrane. They have been implicated in various functions in both health and disease, including intercellular communication, antigen presentation, prion transmis
Externí odkaz:
https://doaj.org/article/5b4c396c9e5f4891ae3a7ecb40bb22e2
Microtubules depolymerization caused by the CK1 inhibitor IC261 may be not mediated by CK1 blockage.
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100090 (2014)
The ubiquitously expressed serine/threonine specific casein kinase 1 (CK1) family plays important roles in the regulation of various physiological processes. Small-molecule inhibitors, such as the CK1δ/ε selectively inhibitor IC261, have been used
Externí odkaz:
https://doaj.org/article/7b3a723808894499a8a48ffc0ff8eeab
Autor:
Ruth Rollason, Katie Dunstan, Peter G Billcliff, Paul Bishop, Paul Gleeson, Helen Wise, Paul Digard, George Banting
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75680 (2013)
CD317/tetherin (aka BST2 or HM1.24 antigen) is an interferon inducible membrane protein present in regions of the lipid bilayer enriched in sphingolipids and cholesterol (often termed lipid rafts). It has been implicated in an eclectic mix of cellula
Externí odkaz:
https://doaj.org/article/1d61ca2e839a4f198d470ebb3c46b1a8
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32386 (2012)
The inositol (1,4,5) trisphosphate 3-kinases comprise a family of enzymes (A, B, and C) that phosphorylate the calcium mobilising molecule inositol (1,4,5) trisphosphate (IP(3)) to generate inositol (1,3,4,5) tetrakisphosphate. This molecule can func
Externí odkaz:
https://doaj.org/article/9f0c330a81d847d09e083e7e5b943ac9
Autor:
Jawad Khalil, James L Hutchinson, George Banting, David Lee Phillips, Christopher Williams, Stephen Cross, Alastair W. Poole, Ting Sun, Dominic Alibhai, Alan D. Leard, Yong Li, Lei Zhang, Richard Seager, Caroline M McKinnon, Stuart J. Mundell, Riyaad Aungraheeta, Richard B. Sessions, Xiaojuan Zhao, Kaya Olzak
Publikováno v:
Blood Adv
Zhao, X, Alibhai, D R, Khalil, J S, Williams, C M, Li, Y, Sessions, R B, Cross, S, Seager, R A, Aungraheeta, M S R H, Leard, A D, McKinnon, C M, Phillips, D J, Poole, A W, Banting, G S & Mundell, S J 2021, ' Tetherin/BST2, a physiologically and therapeutically relevant regulator of platelet receptor signalling ', Blood Advances, vol. 5, no. 7, pp. 1884–1898 . https://doi.org/10.1182/bloodadvances.2020003182
Zhao, X, Alibhai, D R, Khalil, J S, Williams, C M, Li, Y, Sessions, R B, Cross, S, Seager, R A, Aungraheeta, M S R H, Leard, A D, McKinnon, C M, Phillips, D J, Poole, A W, Banting, G S & Mundell, S J 2021, ' Tetherin/BST2, a physiologically and therapeutically relevant regulator of platelet receptor signalling ', Blood Advances, vol. 5, no. 7, pp. 1884–1898 . https://doi.org/10.1182/bloodadvances.2020003182
The reactivity of platelets, which play a key role in the pathogenesis of atherothrombosis, is tightly regulated. The integral membrane protein tetherin/bone marrow stromal antigen-2 (BST-2) regulates membrane organization, altering both lipid and pr
Autor:
George Banting, J. Paul Luzio
The cell is a dynamic entity. Cells are not simply building blocks that are linked together to create an organism: each cell comprises a dynamic network of interacting macromolecules. Just how dynamic has been brought home by recent advances in cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca1a35011a57f5ac18390ed3e4f1359c
https://doi.org/10.1093/med/9780198746690.003.0029
https://doi.org/10.1093/med/9780198746690.003.0029
Autor:
Derek N. Woolfson, Lorna Hodgson, Holly Baum, Joseph L. Beesley, Paul Verkade, George Banting
Publikováno v:
Beesley, J, Baum, H, Hodgson, L, Verkade, P, Banting, G & Woolfson, D 2018, ' Modifying self-assembled peptide cages to control internalization into mammalian cells ', Nano Letters . https://doi.org/10.1021/acs.nanolett.8b02633
Nanoparticles can be used to transport a variety of biological cargoes into eukaryotic cells. Polypeptides provide a versatile material for constructing such systems. Previously, we have assembled nanoscale peptide cages (SAGEs) from de novo designed
Correction to Modifying Self-Assembled Peptide Cages To Control Internalization into Mammalian Cells
Autor:
Derek N. Woolfson, Holly Baum, Paul Verkade, Joseph L. Beesley, Lorna Hodgson, George Banting
Publikováno v:
Nano letters. 19(5)
Publikováno v:
Biology Open
Biology Open, Vol 2, Iss 11, Pp 1253-1263 (2013)
Biology Open, Vol 2, Iss 11, Pp 1253-1263 (2013)
Summary The integral membrane protein CD317/tetherin has been associated with a plethora of biological processes, including restriction of enveloped virus release, regulation of B cell growth, and organisation of membrane microdomains. CD317 possesse