Zobrazeno 1 - 10
of 22
pro vyhledávání: '"George B. Thornton"'
Autor:
Ekaterina Dadachova, Scott G. Kitchen, Gregory Bristol, Gayle Cocita Baldwin, Ekaterina Revskaya, Cyril Empig, George B. Thornton, Miroslaw K. Gorny, Susan Zolla-Pazner, Arturo Casadevall
Publikováno v:
PLoS ONE, Vol 7, Iss 8 (2012)
Externí odkaz:
https://doaj.org/article/a4f17d93d20f4a1d942d335d8970254a
Autor:
Giane A. Oliveira, Michael L. Corado, Elizabeth Nardin, Ashley J. Birkett, George B. Thornton, Kristiane Wetzel, Annette Schmidt, Carolin Maier, Pramod Sarpotdar, J. Mauricio Calvo-Calle
Publikováno v:
Infection and Immunity. 72:6519-6527
We report the first phase I trial to assess the safety and immunogenicity of a malaria vaccine candidate, ICC-1132 (Malarivax), composed of a modified hepatitis B virus core protein (HBc) containing minimal epitopes of thePlasmodium falciparumcircums
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6142a32f11b73968ec2b1d164a1ce64
https://doi.org/10.1128/iai.72.11.6519-6527.2004
https://doi.org/10.1128/iai.72.11.6519-6527.2004
Publikováno v:
Journal of Biological Chemistry. 270:696-699
In addition to its role in hemostasis, fibrinogen is obligatorily required to mount competent inflammatory responses in vivo. A molecular prerequisite of fibrinogen-dependent inflammation may reside in its ability to associate with intercellular adhe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4b87d391841fc53099b9c2e4c4353b2
https://doi.org/10.1074/jbc.270.2.696
https://doi.org/10.1074/jbc.270.2.696
Autor:
Ekaterina Dadachova, Scott G. Kitchen, Gregory Bristol, Gayle Cocita Baldwin, Ekaterina Revskaya, Cyril Empig, George B. Thornton, Miroslaw K. Gorny, Susan Zolla-Pazner, Arturo Casadevall
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 8 (2012)
PLoS ONE, Vol 7, Iss 8 (2012)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dcbb7bcff2b0e0a1ceea01a07bf3e41
http://europepmc.org/articles/PMC3414582
http://europepmc.org/articles/PMC3414582
Autor:
Eileen Garratty, N Dunlop, Dennis R. Burton, Paul W. H. I. Parren, Raju Koduri, George B. Thornton, R. Michael Hendry, Stephen J. Sharp, John P. Moore, Michael Lamacchia, Jayashree Pyati, Peter L. Nara, Lynette S. W. Sawyer, Yvonne J. Bryson, Carlos F. Barbas, David D. Ho, Yunzhen Cao, E. Richard Stiehm
Publikováno v:
Science. 266:1024-1027
The ability of antibodies to neutralize diverse primary isolates of human immunodeficiency virus-type 1 in vitro has been questioned, with implications for the likely efficacy of vaccines. A recombinant human antibody to envelope glycoprotein gp120 w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8be5ac9d2b097c236ec780b8edd3af5a
https://doi.org/10.1126/science.7973652
https://doi.org/10.1126/science.7973652
Autor:
M A Duchosal, Carlos F. Barbas, Roger H. Caothien, George B. Thornton, Sabine A. Eming, Peter Fischer, Didier Leturcq, Patricia J. McConahey, Frank J. Dixon, Dennis R. Burton
Publikováno v:
Nature. 355:258-262
ANTIBODIES are usually prepared from recently boosted animals and reflect ongoing immune responses1–6. In humans, this is restrictive as ethical constraints generally prevent antigen-boosting. Therefore the rich memory compartment of human antibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1578d6ef15968e38acf4dbf299c9c035
https://doi.org/10.1038/355258a0
https://doi.org/10.1038/355258a0
Autor:
Joyce E. Jones, Anneke K. Raney, Toshiyuki Maruyama, Janice Hughes, Richard A. Houghten, Alan McLachlan, George B. Thornton, David R. Milich
Publikováno v:
Proceedings of the National Academy of Sciences. 88:4348-4352
Studies in hepatitis B e antigen (HBeAg)-expressing transgenic mice indicate that self tolerance to two T-cell determinants on the same transgenic self molecule can differ markedly. The dominant T-cell site on HBeAg is tolerogenic, whereas a proporti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce5362d1942f5336046ad2c179e25d60
https://doi.org/10.1073/pnas.88.10.4348
https://doi.org/10.1073/pnas.88.10.4348
Autor:
H. Weiler, Ashley J. Birkett, Meike Hensmann, Elizabeth Nardin, Jan A.M. Langermans, George B. Thornton, Filip Dubovsky, Annette Schmidt, Richard A. W. Vervenne, J. Mauricio Calvo-Calle, Alan W. Thomas
Publikováno v:
Vaccine. 23(41)
ICC-1132 is a malaria vaccine candidate based on a modified hepatitis B virus core particle (HBc) bearing putative protective epitopes from the circumsporozoite protein (CS) of Plasmodium falciparum. While the epitope carrier itself is immunogenic, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4cfb09fc8286b84606633679498592c
https://pubmed.ncbi.nlm.nih.gov/15998554
https://pubmed.ncbi.nlm.nih.gov/15998554
Autor:
Susanna Dunachie, Robert E. Sinden, Jenni M. Vuola, Angela Hunt-Cooke, Ian D. Poulton, Carolin Maier, Eveline L. Tierney, Tamara Berthoud, Sheila M. Keating, George B. Thornton, Filip Dubovsky, Daniel P. Webster, Geoffrey Butcher, Simon Correa, Adrian V. S. Hill, Sarah C. Gilbert, Rikke Fredslund Andersen, Michael Walther, Annette Schmidt, Laura Andrews, Pramod Sarpotdar, Jack Williams
Publikováno v:
Vaccine. 23(7)
ICC-1132, a recombinant virus-like particle comprising of a modified hepatitis B core protein with a B cell (NANP) and two T cell epitopes of Plasmodium falciparum circumsporozoite protein (CSP), was administered i.m. as a single 50 microg dose in Se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c407cacd30f01af39e3502fcdb6d7e
https://pubmed.ncbi.nlm.nih.gov/15603885
https://pubmed.ncbi.nlm.nih.gov/15603885
Autor:
Alain Duperray, Lucia R. Languino, Dario C. Altieri, Karen J. Joganic, George B. Thornton, Mara Fornaro
Although primarily recognized for its role in hemostasis, fibrinogen is also required for competent inflammatory reactions in vivo. It is now shown that fibrinogen promotes adhesion to and migration across an endothelial monolayer of terminally diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f28b7ee27d51ebfb9ffd5bbb7eb85b
https://europepmc.org/articles/PMC42548/
https://europepmc.org/articles/PMC42548/
