Zobrazeno 1 - 10
of 25
pro vyhledávání: '"George B. Naff"'
Publikováno v:
Ciba Foundation Symposium-Complement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c6ad9e7941f0ba77a952e506a0920c0
https://doi.org/10.1002/9780470719381.ch4
https://doi.org/10.1002/9780470719381.ch4
Autor:
Robert E. Galloway, George H. Goldsmith, Thomas Butler, Hidehiko Saito, Jack Levin, Sissay Awoke, Craig K. Wallace, George B. Naff
Publikováno v:
The American Journal of Medicine. 63:933-938
Fifteen patients with Borrelia recurrentis infection were studied to evaluate the role of certain plasma proteins and endotoxin in the pathophysiology of both the acute illness and the Jarisch-Herxheimer-like reaction. The causative spirochetes disap
Autor:
George B. Naff, R. W. Kellermeyer
Publikováno v:
Arthritis & Rheumatism. 18:765-770
Publikováno v:
The Journal of Trauma: Injury, Infection, and Critical Care. 28:1295-1300
This study examines the effects of complement activation and of complement-induced oxygen radical production on the principal determinant of hepatic function, i.e., effective hepatic blood flow (EHBF). Female Sprague-Dawley rats received cobra venom
Autor:
George B. Naff, Jeanne E. Anderson, Chester A. Alper, Jeffrey J. Wisnieski, Michael H. Nathanson, Alvin E. Davis
Publikováno v:
Arthritis & Rheumatism. 30:919-926
We studied a kindred in which C4 deficiency had been discovered. Unlike families with total absence of C4, in this kindred C4 deficiency was found to be incomplete, autosomal dominant, not caused by null alleles, and not associated with a high incide
Publikováno v:
Journal of Surgical Research. 45:28-36
Intravascular complement activation with either zymosan or cobra venom factor (CVF) impairs hepatic blood flow. Oxygen radical scavengers given at the time of complement activation attenuate the resulting hepatic ischemia. It is not clear whether com
Autor:
George B. Naff, Oscar D. Ratnoff
Publikováno v:
Journal of Experimental Medicine. 125:337-358
The formation of C'1 esterase from C'1, the first component of complement, may be brought about by the action of plasmin or trypsin upon C'1s, a subcomponent of C'1. These enzymes also decrease the esterolytic activity of C'1 esterase. The formation
Autor:
Oscar D. Ratnoff, George B. Naff
Publikováno v:
The Journal of Experimental Medicine
Human C'1, a macromolecular complex composed of three subunits, is the zymogen for at least two distinct enzymes. Preparations of one subunit, C'1r, functioned as a protease which converted another subunit, C'1s, to C'1 esterase. The conversion of C'
Publikováno v:
Journal of Clinical Investigation. 50:642-649
Kidney tissue from 97 patients was studied by immunofluorescent techniques using antiserum to purified properdin. All patients with acute poststreptococcal glomerulonephritis showed deposition of properdin and the third component of complement (C3),
Publikováno v:
The Journal of Experimental Medicine
The fraction of human serum designated as C'1 esterase inhibitor is known to inhibit the action of C'1 esterase, a plasma kallikrein, and PF/Dil, an enzyme in plasma enhancing cutaneous vascular permeability. In the present study, C'1 esterase inhibi