Zobrazeno 1 - 10
of 18
pro vyhledávání: '"George B, Sigal"'
Autor:
Victoria Huang, Jennifer Roem, Derek K. Ng, Jamie McElrath Schwartz, Allen D. Everett, Nikhil Padmanabhan, Daniel Romero, Jessica Joe, Christopher Campbell, George B. Sigal, Jacob N. Wohlstadter, Melania M. Bembea
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract In this two-center prospective cohort study of children on ECMO, we assessed a panel of plasma brain injury biomarkers using exploratory factor analysis (EFA) to evaluate their interplay and association with outcomes. Biomarker concentration
Externí odkaz:
https://doaj.org/article/8804e732b0b449efa92e101c2eb34350
Autor:
Jamie McElrath Schwartz, Derek K. Ng, Jennifer Roem, Nikhil Padmanabhan, Daniel Romero, Jessica Joe, Christopher Campbell, George B. Sigal, Jacob N. Wohlstadter, Allen D. Everett, Melania M. Bembea
Publikováno v:
Resuscitation Plus, Vol 18, Iss , Pp 100609- (2024)
Aim: We sought to determine if higher plasma levels of brain injury biomarkers neurofilament light (NfL), phosphorylated tau 181 (pT181), tau, and ubiquitin C-terminal hydrolase L1 (UCHL1) were associated with unfavorable outcomes in children support
Externí odkaz:
https://doaj.org/article/834ff6633e5849379b68c26e6921c362
Autor:
Michail Spanos, Sigal Shachar, Thadryan Sweeney, H. Immo Lehmann, Priyanka Gokulnath, Guoping Li, George B. Sigal, Rajini Nagaraj, Pradeepthi Bathala, Farhan Rana, Ravi V. Shah, David A. Routenberg, Saumya Das
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104833- (2022)
Summary: Patients with SARS-CoV-2 infection (COVID-19) risk developing long-term neurologic symptoms after infection. Here, we identify biomarkers associated with neurologic sequelae one year after hospitalization for SARS-CoV-2 infection. SARS-CoV-2
Externí odkaz:
https://doaj.org/article/038a4058d8e64404a52471da81c08966
Autor:
Leah G Jarsberg, Komal Kedia, Jason Wendler, Aaron T Wright, Paul D Piehowski, Marina A Gritsenko, Tujin Shi, David M Lewinsohn, George B Sigal, Marc H Weiner, Richard D Smith, Joseph Keane, Jon M Jacobs, Payam Nahid
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0250586 (2021)
IntroductionContemporary phase 2 TB disease treatment clinical trials have found that microbiologic treatment responses differ between African versus non-African regions, the reasons for which remain unclear. Understanding host and disease phenotypes
Externí odkaz:
https://doaj.org/article/b9145d89909b47d4854d0bccdbebc6ef
Autor:
Annie Ren, Dorsa Sohaei, Antigona Ulndreaj, Oscar D. Pons-Belda, Amaia Fernandez-Uriarte, Ioannis Zacharioudakis, George B. Sigal, Martin Stengelin, Anu Mathew, Christopher Campbell, Nikhil Padmanabhan, Daniel Romero, Jessica Joe, Antoninus Soosaipillai, Vathany Kulasingam, Tony Mazzulli, Xinliu A. Li, Allison McGeer, Eleftherios P. Diamandis, Ioannis Prassas
Publikováno v:
Clinical Chemistry and Laboratory Medicine (CCLM). 60:771-777
Objectives Widespread SARS-CoV-2 testing is invaluable for identifying asymptomatic/pre-symptomatic individuals. There remains a technological gap for highly reliable, easy, and quick SARS-CoV-2 diagnostic tests suitable for frequent mass testing. Co
Autor:
Lisa Koeppel, Claudia M Denkinger, Romain Wyss, Tobias Broger, Novel N Chegou, Jill M Dunty, Kerry Scott, Tatiana Cáceres, Elloise Dutoit, Cesar Ugarte-Gil, Mark Nicol, Eduardo Gotuzzo, Paul L A M Corstjens, Annemieke Geluk, George B Sigal, Emmanuel Moreau, Audrey Albertini, Anna Mantsoki, Stefano Ongarello, Gerhard Walzl, Marta Fernandez Suarez
The current four symptom screen recommended by the WHO is widely used as screen to initiate diagnostic testing for active pulmonary tuberculosis (TB), yet the performance is poor especially when TB prevalence is low. In contrast, more sensitive molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff80a491c4eddf995814ff02dbc89eb6
https://doi.org/10.1101/2023.01.31.23285229
https://doi.org/10.1101/2023.01.31.23285229
Autor:
Tobias Broger, Michael Tsionksy, Anu Mathew, Todd L Lowary, Abraham Pinter, Tatiana Plisova, Daniel Bartlett, Simone Barbero, Claudia M Denkinger, Emmanuel Moreau, Kiyonori Katsuragi, Masanori Kawasaki, Payam Nahid, George B Sigal
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215443 (2019)
BackgroundTuberculosis (TB) infection was responsible for an estimated 1.3 million deaths in 2017. Better diagnostic tools are urgently needed. We sought to determine whether accurate TB antigen detection in blood or urine has the potential to meet t
Externí odkaz:
https://doaj.org/article/151ed0302cc54ea6b05a82ddb095acf5
Autor:
Daniel Solis, Mamdouh Sibai, Faith Kung, Timothy J. Break, Seth B. Harkins, ChunHong Huang, Fumiko Yamamoto, Malaya K. Sahoo, Jacob N. Wohlstadter, George B. Sigal, Benjamin A. Pinsky
Publikováno v:
Journal of Clinical Virology. 162:105444
Autor:
George B. Sigal, Tanya Novak, Anu Mathew, Janet Chou, Yubo Zhang, Navaratnam Manjula, Predeepthi Bathala, Jessica Joe, Nikhil Padmanabhan, Daniel Romero, Gabriella Allegri-Machado, Jill Joerger, Laura L. Loftis, Stephanie P. Schwartz, Tracie C. Walker, Julie C. Fitzgerald, Keiko M. Tarquinio, Matt S. Zinter, Jennifer E. Schuster, Natasha B. Halasa, Melissa L. Cullimore, Aline B. Maddux, Mary A. Staat, Katherine Irby, Heidi R. Flori, Bria M. Coates, Hillary Crandall, Shira J. Gertz, Adrienne G. Randolph, Nira R. Pollock
Publikováno v:
medRxiv : the preprint server for health sciences.
BackgroundDetection of SARS-CoV-2 antigens in blood has high sensitivity in adults with acute COVID-19, but sensitivity in pediatric patients is unclear. Recent data suggest that persistent SARS-CoV-2 spike antigenemia may contribute to multisystem i
Autor:
George B, Sigal, Tanya, Novak, Anu, Mathew, Janet, Chou, Yubo, Zhang, Navaratnam, Manjula, Pradeepthi, Bathala, Jessica, Joe, Nikhil, Padmanabhan, Daniel, Romero, Gabriella, Allegri-Machado, Jill, Joerger, Laura L, Loftis, Stephanie P, Schwartz, Tracie C, Walker, Julie C, Fitzgerald, Keiko M, Tarquinio, Matt S, Zinter, Jennifer E, Schuster, Natasha B, Halasa, Melissa L, Cullimore, Aline B, Maddux, Mary A, Staat, Katherine, Irby, Heidi R, Flori, Bria M, Coates, Hillary, Crandall, Shira J, Gertz, Adrienne G, Randolph, Nira R, Pollock
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
Background Detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigens in blood has high sensitivity in adults with acute coronavirus disease 2019 (COVID-19), but sensitivity in pediatric patients is unclear. Recent data sugges