The Arab Awakening: The Story of the Arab National Movement (Classic Reprint)

Autor: George Antonius

Excerpt from The Arab Awakening: The Story of the Arab National Movement (Classic Reprint)The frequent risings and upheavals which, in the preceding three centuries, had stirred the Arab world from its torpid passivity under Ottoman dominance do not

Expression of the p16(INK4a) gene product, methylation of the p16(INK4a) promoter region and expression of the polycomb-group gene BMI-1 in squamous cell lung carcinoma and premalignant endobronchial lesions

Autor: Pieter E. Postmus, Roderick H.J. Breuer, Egbert F. Smit, Arie P. Otte, Richard George Antonius Bernardus Sewalt, C. J. L. M. Meijer, Frank M. Raaphorst, Peter J.F. Snijders, G. Sutedja

Publikováno v: Lung Cancer, 48, 299-306. Elsevier
Breuer, RH, Snijders, P J F, Sutedja, G T, Sewalt, RG, Otte, AP, Postmus, P E, Meijer, C J L M, Raaphorst, F M & Smit, E F 2005, ' Expression of the p16(INK4a) gene product, methylation of the p16(INK4a) promoter region and expression of the polycomb-group gene BMI-1 in squamous cell lung carcinoma and premalignant endobronchial lesions ', Lung Cancer, vol. 48, no. 3, pp. 299-306 . https://doi.org/10.1016/j.lungcan.2004.11.026
Lung Cancer, 48(3), 299-306. Elsevier Ireland Ltd

It is generally assumed that squamous cell carcinoma develops in a stepwise manner from normal bronchial epithelium towards cancer by the accumulation of (epi)genetic alterations. Several mechanisms including mutations and homozygous deletions or hyp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8b4216cc33ffb85b762bbbfae36e5a3
https://hdl.handle.net/11245/1.241556

Increased Expression of the EZH2 Polycomb Group Gene in BMI-1-Positive Neoplastic Cells during Bronchial Carcinogenesis

Autor: Arie P. Otte, Richard George Antonius Bernardus Sewalt, Folkert J. van Kemenade, Pieter E. Postmus, Peter J.F. Snijders, Thomas G. Sutedja, Egbert F. Smit, Roderick H.J. Breuer, Chris J.L.M. Meijer, Frank M. Raaphorst

Publikováno v: Neoplasia, 6, 736-743. Elsevier
Neoplasia: An International Journal for Oncology Research, Vol 6, Iss 6, Pp 736-743 (2004)

Polycomb group (PcG) genes are responsible for maintenance of cellular identity and contribute to regulation of the cell cycle. Recent studies have identified several PcG genes as oncogenes, and a role for PcG proteins in human oncogenesis is suspect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea255230af8a18f18257b79b5a02057f
https://doi.org/10.1593/neo.04160

The Arab Awakening : The Story of the National Arab Movement

Autor: George Antonius

First published in 1938, this fine book is the first study of the Arab national movement ever written.'The whole of this brilliantly written book moves at the same plane of objective and critical scholarship.'Daily Telegraph, London.'A good book writ

Selective Interactions between Vertebrate Polycomb Homologs and the SUV39H1 Histone Lysine Methyltransferase Suggest that Histone H3-K9 Methylation Contributes to Chromosomal Targeting of Polycomb Group Proteins

Autor: Arie P. Otte, Thijs Hendrix, Richard George Antonius Bernardus Sewalt, Dieter Schweizer, Martin Melcher, Monika Lachner, Karien M. Hamer, Mark Vargas, Jan L. den Blaauwen, Thomas Jenuwein

Publikováno v: Molecular and Cellular Biology. 22:5539-5553

Polycomb group (PcG) proteins form multimeric chromatin-associated protein complexes that are involved in heritable repression of gene activity. Two distinct human PcG complexes have been characterized. The EED/EZH2 PcG complex utilizes histone deace

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bace20ef47010be248e82a4ea8269d40
https://doi.org/10.1128/mcb.22.15.5539-5553.2002