Zobrazeno 1 - 10
of 348
pro vyhledávání: '"George A. Stouffer"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Atherosclerosis is rare in internal thoracic arteries (ITA) even in patients with severe atherosclerotic coronary artery (ACA) disease. To explore cellular differences, ITA SMC from 3 distinct donors and ACA SMC from 3 distinct donors were g
Externí odkaz:
https://doaj.org/article/0fa4856e1ea54e97a8a918d85f27ba31
Autor:
Kayla R. Tunehag, Cameron D. Thomas, Francesco Franchi, Joseph S. Rossi, Ellen C. Keeley, R. David Anderson, Amber L. Beitelshees, Julio D. Duarte, Yan Gong, Richard A. Kerensky, Caitrin W. McDonough, Anh B. Nguyen, Luis Ortega‐Paz, Sanjay Venkatesh, Yehua Wang, Julie A. Johnson, Almut G. Winterstein, George A. Stouffer, Dominick J. Angiolillo, Larisa H. Cavallari, Craig R. Lee
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 12 (2024)
Background Cytochrome P450 2C19 (CYP2C19) intermediate and poor metabolizer patients exhibit diminished clopidogrel clinical effectiveness after percutaneous coronary intervention (PCI). However, outcome studies to date have lacked racial diversity.
Externí odkaz:
https://doaj.org/article/50016bae702e4bcbb5b7ae35deb0f244
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Dual antiplatelet therapy with a P2Y12 inhibitor (clopidogrel, prasugrel, or ticagrelor) and aspirin remains the standard of care for all patients undergoing percutaneous coronary intervention (PCI). It is well-established that patients carrying CYP2
Externí odkaz:
https://doaj.org/article/32b6f9ead6864846850e7649e32d9567
Publikováno v:
Journal of the Society for Cardiovascular Angiography & Interventions, Vol 1, Iss 2, Pp 100029- (2022)
Externí odkaz:
https://doaj.org/article/fbd073177d534f52a7fa4720344f4ae0
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Cyr61 is a member of the CCN family of proteins that is expressed in atherosclerotic lesions and regulated by angiotensin II. It is unknown whether renal artery stenosis (RAS) increases Cyr61 expression. Male ApoE−/− mice were randomized
Externí odkaz:
https://doaj.org/article/3821fd40f44746c6aecf9ba0bd0c0704
Autor:
Amber L. Beitelshees, Cameron D. Thomas, Philip E. Empey, George A. Stouffer, Dominick J. Angiolillo, Francesco Franchi, Sony Tuteja, Nita A. Limdi, James C. Lee, Julio D. Duarte, Rolf P. Kreutz, Todd C. Skaar, James C. Coons, Jay Giri, Caitrin W. McDonough, Rachel Rowland, James M. Stevenson, Thuy Thai, Mark R. Vesely, Jacob T. Wellen, Julie A. Johnson, Almut G. Winterstein, Larisa H. Cavallari, Craig R. Lee
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 4 (2022)
Background Studies have demonstrated increased risk of major atherothrombotic events in CYP2C19 loss‐of‐function (LOF) variant carriers versus non‐carriers treated with clopidogrel after percutaneous coronary intervention (PCI). We sought to ev
Externí odkaz:
https://doaj.org/article/fdde104f3e8e43f68d0603d9571a4e08
Publikováno v:
JACC: Case Reports, Vol 2, Iss 10, Pp 1470-1474 (2020)
We describe the case of a 42-year-old female with recurrent left ventricular (LV) thrombus and multiple embolic events despite having normal LV systolic function. The clinical presentation, associated conditions, diagnostic evaluation and treatment o
Externí odkaz:
https://doaj.org/article/2007e34d702244949e0171848c33e000
Autor:
Sameer Arora, George A. Stouffer, Anna Kucharska‐Newton, Muthiah Vaduganathan, Arman Qamar, Kunihiro Matsushita, Dhaval Kolte, Harmony R. Reynolds, Sripal Bangalore, Wayne D. Rosamond, Deepak L. Bhatt, Melissa C. Caughey
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 19 (2018)
Background Standardization of evidence‐based medical therapies has improved outcomes for patients with non–ST‐segment–elevation myocardial infarction (NSTEMI). Although racial differences in NSTEMI management have previously been reported, it
Externí odkaz:
https://doaj.org/article/02d84ebe0174485199916a8fa8940dd4
Autor:
Akinyemi Oni-Orisan, Matthew L. Edin, John Andrew Lee, Michael A. Wells, Erin S. Christensen, Kimberly C. Vendrov, Fred B. Lih, Kenneth B. Tomer, Xue Bai, Joan M. Taylor, George A. Stouffer, Darryl C. Zeldin, Craig R. Lee
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 1, Pp 109-119 (2016)
Cytochrome P450 (CYP)-derived epoxyeicosatrienoic acids (EETs) exhibit potent cardiovascular protective effects in preclinical models, and promoting the effects of EETs has emerged as a potential therapeutic strategy for coronary artery disease (CAD)
Externí odkaz:
https://doaj.org/article/4f2cb1647d1e4547a04094c60e98c261
Autor:
Sameer Arora, Paula D. Strassle, Arman Qamar, Evan N. Wheeler, Alexandra L. Levine, Jacob A. Misenheimer, Matthew A. Cavender, George A. Stouffer, Prashant Kaul
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 7 (2018)
BackgroundThe International Classification of Diseases (ICD) coding system does not recognize type 2 myocardial infarction (MI) as a separate entity; therefore, patients with type 2 MI continue to be categorized under the general umbrella of non–ST
Externí odkaz:
https://doaj.org/article/45ec029b80b44b1bbcd2633f8f7891dc