Zobrazeno 1 - 10
of 106
pro vyhledávání: '"George A. Beck"'
Autor:
Sreedhara Sangadala, Chi Heon Kim, Lorenzo M Fernandes, Pooja Makkar, George R Beck, Scott D Boden, Hicham Drissi, Steven M Presciutti
Publikováno v:
eLife, Vol 12 (2023)
Background: The clinical healing environment after a posterior spinal arthrodesis surgery is one of the most clinically challenging bone-healing environments across all orthopedic interventions due to the absence of a contained space and the need to
Externí odkaz:
https://doaj.org/article/f938d673b72c40d2acd5d55d22983de8
Autor:
Joseph L. Roberts, Mingcan Yu, Manjula Viggeswarapu, Jamie L. Arnst, Roberto Pacifici, George R. Beck Jr
Publikováno v:
JCI Insight, Vol 8, Iss 10 (2023)
The intake of dietary phosphate far exceeds recommended levels; however, the long-term health consequences remain relatively unknown. Here, the chronic physiological response to sustained elevated and reduced dietary phosphate consumption was investi
Externí odkaz:
https://doaj.org/article/ad4a4086c828464eac336155a4505759
Autor:
Nancy H. Colburn, Matthew R. Young, George R. Beck, Christine M. Perella, Alyson R. Baker, Alysia M. Birkholz, Connie P. Matthews
Supplementary Figures 1-3, Tables 1-2 from Dominant-Negative Activator Protein 1 (TAM67) Targets Cyclooxygenase-2 and Osteopontin under Conditions in which It Specifically Inhibits Tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b16780135abd4693f9fd3e88675bd67d
https://doi.org/10.1158/0008-5472.22365828
https://doi.org/10.1158/0008-5472.22365828
Autor:
Nancy H. Colburn, Matthew R. Young, George R. Beck, Christine M. Perella, Alyson R. Baker, Alysia M. Birkholz, Connie P. Matthews
Activation of activator protein 1 (AP-1) and nuclear factor κB (NFκB)–dependent transcription is required for tumor promotion in cell culture models and transgenic mice. Dominant-negative c-Jun (TAM67) blocks AP-1 activation by dimerizing with Ju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47217f02b39d0d866db4ba50c2f351b3
https://doi.org/10.1158/0008-5472.c.6494877.v1
https://doi.org/10.1158/0008-5472.c.6494877.v1
Autor:
Lorenzo M. Fernandes, Steven M. Presciutti, Hicham Drissi, Pooja Makkar, Chi Heon Kim, George R. Beck, Scott D. Boden, Sreedhara Sangadala
BackgroundThe healing environment within the posterolateral lumbar spine is one of the most clinically challenging bone healing environments in all of orthopaedics due to a lack of a contained space and the need to formde novobone in a non-bony envir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e1be1964f9f5338e11fb400126f242d
https://doi.org/10.1101/2021.08.12.456145
https://doi.org/10.1101/2021.08.12.456145
Autor:
Seong-Ho Hong, Arash Minai-Tehrani, Seung-Hee Chang, Hu-Lin Jiang, Somin Lee, Ah-Young Lee, Hwi Won Seo, Chanhee Chae, George R Beck, Myung-Haing Cho
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
[This corrects the article DOI: 10.1371/journal.pone.0077121.].
Externí odkaz:
https://doaj.org/article/ad74b8ff92654f7085d59ecc59ac3755
Knockdown of the sodium-dependent phosphate co-transporter 2b (NPT2b) suppresses lung tumorigenesis.
Autor:
Seong-Ho Hong, Arash Minai-Tehrani, Seung-Hee Chang, Hu-Lin Jiang, Somin Lee, Ah-Young Lee, Hwi Won Seo, Chanhee Chae, George R Beck, Myung-Haing Cho
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77121 (2013)
The sodium-dependent phosphate co-transporter 2b (NPT2b) plays an important role in maintaining phosphate homeostasis. In previous studies, we have shown that high dietary inorganic phosphate (Pi) consumption in mice stimulated lung tumorigenesis and
Externí odkaz:
https://doaj.org/article/c3d3610e1e4b4914ab9a2074afd2b2f0
Autor:
George R. Beck, Jamie L. Arnst
Publikováno v:
Biochem Pharmacol
Phosphorus, often in the form of inorganic phosphate (Pi), is critical to cellular function on many levels; it is required as an integral component of kinase signaling, in the formation and function of DNA and lipids, and energy metabolism in the for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98c9a20069230b4cd4538a2adb764a55
https://europepmc.org/articles/PMC9667393/
https://europepmc.org/articles/PMC9667393/
Bioactive effects of silica nanoparticles on bone cells are size, surface, and composition dependent
Publikováno v:
Acta Biomater
Silica based nanoparticles have been demonstrated to have intrinsic biologic activity towards the skeleton and to function by promoting the differentiation of bone forming osteoblasts while inhibiting the differentiation of bone resorbing osteoclasts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f414bba278f05baaaf7fe671a1cce688
https://doi.org/10.1016/j.actbio.2018.10.018
https://doi.org/10.1016/j.actbio.2018.10.018
Autor:
Roberto Pacifici, Timothy F. Lane, Mark M. Habib, Susanne Roser-Page, Daiana Weiss, M. Neale Weitzmann, George R. Beck, Tatyana Vikulina
Publikováno v:
Annals of the New York Academy of Sciences. 1415:21-33
Activated lymphocytes promote inflammation and bone destruction in rheumatoid arthritis (RA), making T cells and B cells therapeutic targets. Indeed, pharmacological blockade of CD28 costimulation using CTLA-4Ig (abatacept), approved for amelioration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d95385f48451695cc81e098856419eb7
https://doi.org/10.1111/nyas.13643
https://doi.org/10.1111/nyas.13643