Zobrazeno 1 - 7
of 7
pro vyhledávání: '"George A. Basler"'
Autor:
Anna Maria Casazza, Pamela A. Trail, George A. Basler, Alfred R. Crosswell, Saulnier Mark G, William C. Rose
Publikováno v:
Investigational New Drugs. 8:S25-S32
BMY-40481-30 is a new, water-soluble derivative and probable prodrug of etoposide characterized by the presence of a phosphate group in position 4′ of the E ring of the etoposide molecule. The compound was only weakly cytotoxic in vitro and, conseq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e757bad3524eda5edc03350c98f63f3
https://doi.org/10.1007/bf00171981
https://doi.org/10.1007/bf00171981
Autor:
William R. Shapiro, Emile M. Hiesiger, George A. Basler, Lauren E. Lipschutz, Jerome B. Posner, Gail Austin Cooney
Publikováno v:
Journal of neuro-oncology. 8(3)
We used quantitative autoradiography (QAR) to evaluate the effect of systemically administered dexamethasone on capillary permeability in brain tumors and surrounding brain. Rats bearing unilateral right hemispheric C6 gliomas were studied at one and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4394cc5eac531536e06e38c7fb6478a2
https://pubmed.ncbi.nlm.nih.gov/2358852
https://pubmed.ncbi.nlm.nih.gov/2358852
Publikováno v:
JNCI: Journal of the National Cancer Institute. 62:447-453
Seven human brain tumors were transplanted into the brains (6/7 takes) and subcutaneous tissues (7/7 takes) of athymic nude mice. Compared to experimental animal brain tumors, these tumors, taken directly from patients in the operating room and trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62aeba1f2a8dd23a09c5e0ccbc96211b
https://doi.org/10.1093/jnci/62.3.447
https://doi.org/10.1093/jnci/62.3.447
Publikováno v:
Investigational New Drugs. 7:173-178
BMY-28090 is a novel actinomycete fermentation derived antitumor agent. The cytotoxic effect of BMY-28090 was evaluated in two murine and eight human tumor cell lines in vitro. Following 72-hour exposures, BMY-28090 was cytotoxic for all of these cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::487453a78764ac2905a08692996e302c
https://doi.org/10.1007/bf00170854
https://doi.org/10.1007/bf00170854
Publikováno v:
Journal of neuropathology and experimental neurology. 40(5)
Sixteen of 21 human malignant glial tumors were successfully heterotransplanted into the brains of nude mice, and one other was transplanted into the brain after prior subcutaneous heterotransplantation. Most xenografts grew preferentially as diffuse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a2ed85f52d21353cc20c4426b9020ea
https://pubmed.ncbi.nlm.nih.gov/7276991
https://pubmed.ncbi.nlm.nih.gov/7276991
Autor:
L. E. Lipschutz, William R. Shapiro, Jerome B. Posner, E. M. Hiesiger, R. M. Voorhies, George A. Basler
Publikováno v:
Annals of neurology. 19(1)
Using quantitative autoradiography, we investigated the effect of intracarotid infusions of hyperosmolar mannitol solutions on capillary permeability and blood flow. Capillary permeability, expressed in terms of a blood-to-tissue transfer constant (K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f5525dbecb3d1bd9c44f6dedd03048
https://pubmed.ncbi.nlm.nih.gov/3080944
https://pubmed.ncbi.nlm.nih.gov/3080944
Autor:
E. M. Hiesiger, L. E. Lipschutz, Jerome B. Posner, A. Picco-Del Bo, Howard T. Thaler, George A. Basler, William R. Shapiro
Publikováno v:
Neurology. 39:90-90
Using quantitative autoradiography, we investigated the effect of meningeal carcinomatosis on local cerebral glucose utilization (LCGU). A rat model of meningeal carcinomatosis using Walker 256 tumor was used. LCGU was evaluated using 14C-2-deoxy-D-g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a756840dbc8aec60186ec9d66515a02f
https://doi.org/10.1212/wnl.39.1.90
https://doi.org/10.1212/wnl.39.1.90