Zobrazeno 1 - 10
of 42
pro vyhledávání: '"George A Wilkinson"'
Autor:
Sreenivasulu Kilari, Stephanie Cossette, Shabnam Pooya, Michelle Bordas, Yi-Wen Huang, Ramani Ramchandran, George A Wilkinson
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144185 (2015)
Elevated plasma triglycerides are associated with increased susceptibility to heart disease and stroke, but the mechanisms behind this relationship are unclear. A clearer understanding of gene products which influence plasma triglycerides might help
Externí odkaz:
https://doaj.org/article/d79b98ce0c854d208d5567f57ce57411
Autor:
Noah R Leigh, Marcus-Oliver Schupp, Keguo Li, Vakeel Padmanabhan, Adam Gastonguay, Ling Wang, Chang Z Chun, George A Wilkinson, Ramani Ramchandran
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76484 (2013)
The extracellular matrix plays a critical role in neural crest (NC) cell migration. In this study, we characterize the contribution of the novel GPI-linked matrix metalloproteinase (MMP) zebrafish mmp17b. Mmp17b is expressed post-gastrulation in the
Externí odkaz:
https://doaj.org/article/5976424d5d9448498361d5d806c8403d
Autor:
Baofeng Zhao, Ramani Ramchandran, Paula E. North, George A. Wilkinson, Sreenivasulu Kilari, Nader Rahimi, Indulekha Remadevi, Jing Pan, Robert Q. Miao, Ming You
Publikováno v:
Journal of Biological Chemistry. 288:10265-10274
The endothelial cell-specific chemotaxis receptor (ECSCR) is a cell-surface protein selectively expressed by endothelial cells (ECs), with roles in EC migration, apoptosis and proliferation. Our previous study (Verma, A., Bhattacharya, R., Remadevi,
Autor:
Mark Horswill, Ramani Ramchandran, Kallal Pramanik, Rajendra K. Kothinti, Noah R. Leigh, Mathias Francois, Monica Beltrame, George A. Wilkinson, Niloofar M. Tabatabai, Marcus O. Schupp, Ganesh V. Samant, Chang Zoon Chun, Peter Koopman, Suzanna Sellars, Indranil Sinha, Indulekha Remadevi, Silvia Moleri, Keguo Li
Publikováno v:
Journal of Biological Chemistry. 286:30740-30747
Despite their importance as members of the Roundabout (Robo) family in the control of axonal and vascular patterning, the transcriptional regulation of these genes is poorly understood. In this study, we show that members of the Sry-related high mobi
Autor:
Sascha Seidel, Amparo Acker-Palmer, Till Acker, Clara L. Essmann, George A. Wilkinson, Mara E. Pitulescu, Suphansa Sawamiphak
Publikováno v:
Nature
The formation and guidance of specialized endothelial tip cells is essential for both developmental and pathological angiogenesis. Notch-1 signalling regulates the generation of tip cells, which respond to gradients of vascular endothelial growth fac
Autor:
Indulekha Remadevi, Sreenivas Kilari, George A. Wilkinson, Baofeng Baofeng Zhao, Paula E. North, Ming You, Ramani Ramchandran, Nader Rahimi, Jing Pan, Robert Q. Miao
Publikováno v:
The FASEB Journal. 28
The endothelial cell-specific chemotaxis receptor (ECSCR) is a cell-surface protein selectively expressed by endothelial cells (ECs), with roles in EC migration, apoptosis and proliferation. Our pr...
Autor:
Ramani Ramchandran, Chang Z. Chun, George A. Wilkinson, Marcus-Oliver Schupp, Ling Wang, Noah R. Leigh, Adam J. Gastonguay, Vakeel Padmanabhan, Keguo Li
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 10, p e76484 (2013)
PLoS ONE, Vol 8, Iss 10, p e76484 (2013)
The extracellular matrix plays a critical role in neural crest (NC) cell migration. In this study, we characterize the contribution of the novel GPI-linked matrix metalloproteinase (MMP) zebrafish mmp17b. Mmp17b is expressed post-gastrulation in the
Autor:
Nicholas W. Gale, Ralf H. Adams, Francesca Diella, George A. Wilkinson, Cornelia Weiss, Werner Risau, Rüdiger Klein, Urban Deutsch
Publikováno v:
Genes & Development. 13:295-306
Eph receptor tyrosine kinases and their cell-surface-bound ligands, the ephrins, regulate axon guidance and bundling in the developing brain, control cell migration and adhesion, and help patterning the embryo. Here we report that two ephrinB ligands
Autor:
Minjie Hu, Ben A. Barres, Elizabeth G. Munro, Louis F. Reichardt, Anke Meyer-Franke, Alex Krüttgen, Martin G. Hanson, George A Wilkinson
Publikováno v:
Neuron. 21(4):681-693
Here, we describe a novel mechanism for the rapid regulation of surface levels of the neurotrophin receptor TrkB. Unlike nodose ganglion neurons, both retinal ganglion cells (RGCs) and spinal motor neurons (SMNs) in culture display only low levels of
Publikováno v:
Neuron. 21:325-334
Spinal sensory ganglia have been shown to contain neuronal subpopulations with different functions and neurotrophin dependencies. Neurotrophins act, in large part, through Trk receptor tyrosine kinases: nerve growth factor (NGF) via TrkA, brain-deriv