Zobrazeno 1 - 10
of 124
pro vyhledávání: '"George A DosReis"'
Autor:
Thaís S. Rigoni, Natália S. Vellozo, Mariela Cabral-Piccin, Laryssa Fabiano-Coelho, Ulisses G. Lopes, Alessandra A. Filardy, George A. DosReis, Marcela F. Lopes
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Macrophages host Leishmania major infection, which causes cutaneous Leishmaniasis in humans. In the murine model, resistance to infection depends on the host immunity mediated by CD4 T-cell cytokines and macrophages. In association to other stimuli,
Externí odkaz:
https://doaj.org/article/f8b7c695bcd54ce39eef154ea8e0f272
Autor:
Kamila Guimarães-Pinto, Danielle Oliveira Nascimento, Antonia Corrêa-Ferreira, Alexandre Morrot, Celio G. Freire-de-Lima, Marcela F. Lopes, George A. DosReis, Alessandra A. Filardy
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Trypanosoma cruzi infects and replicates within a wide variety of immune and non-immune cells. Here, we investigated early cellular responses induced in NIH-3T3 fibroblasts upon infection with trypomastigote forms of T. cruzi. We show that fibroblast
Externí odkaz:
https://doaj.org/article/82b98e6311864d19b8b48960e36e31d4
Autor:
Fabricio Montalvão, Danielle Oliveira Nascimento, Marise P. Nunes, Carolina M. Koeller, Alexandre Morrot, Leticia Miranda S. Lery, Paulo M. Bisch, Santuza M. R. Teixeira, Rita Vasconcellos, Leonardo Freire-de-Lima, Marcela F. Lopes, Norton Heise, George A. DosReis, Célio Geraldo Freire-de-Lima
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Few studies investigate the major protein antigens targeted by the antibody diversity of infected mice with Trypanosoma cruzi. To detect global IgG antibody specificities, sera from infected mice were immunoblotted against whole T. cruzi extracts. By
Externí odkaz:
https://doaj.org/article/c879b508b68d4d519a59f4bbbf34b088
Autor:
Natália S. Vellozo, Sâmara T. Pereira-Marques, Mariela P. Cabral-Piccin, Alessandra A. Filardy, Flávia L. Ribeiro-Gomes, Thaís S. Rigoni, George A. DosReis, Marcela F. Lopes
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
As key cells, able to host and kill Leishmania parasites, inflammatory monocytes/macrophages are potential vaccine and therapeutic targets to improve immune responses in Leishmaniasis. Macrophage phenotypes range from M1, which express NO-mediated mi
Externí odkaz:
https://doaj.org/article/42f4b55cd2dd468a823c48c74d0aa5c0
Autor:
George A DosReis, Marcela F Lopes
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 104, Pp 259-262 (2009)
Host cell apoptosis plays an important immune regulatory role in parasitic infections. Infection of mice with Trypanosoma cruzi, the causative agent of Chagas disease, induces lymphocyte apoptosis. In addition, phagocytosis of apoptotic cells stimula
Externí odkaz:
https://doaj.org/article/cf3c6713eb834120a504c89d2b3686a5
Autor:
Angélica F Arcanjo, Isabel F LaRocque-de-Freitas, Juliana Dutra B Rocha, Daniel Zamith, Ana Caroline Costa-da-Silva, Marise Pinheiro Nunes, Fabio P Mesquita-Santos, Alexandre Morrot, Alessandra A Filardy, Mario Mariano, Christianne Bandeira-Melo, George A DosReis, Debora Decote-Ricardo, Célio Geraldo Freire-de-Lima
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0124888 (2015)
B-1 cells can be differentiated from B-2 cells because they are predominantly located in the peritoneal and pleural cavities and have distinct phenotypic patterns and activation properties. A mononuclear phagocyte derived from B-1 cells (B-1CDP) has
Externí odkaz:
https://doaj.org/article/f0c309d0961041668728e5877d475053
Autor:
Tatiana Luna-Gomes, Alessandra A Filardy, Juliana Dutra B Rocha, Debora Decote-Ricardo, Isabel Ferreira LaRocque-de-Freitas, Alexandre Morrot, Patrícia T Bozza, Hugo C Castro-Faria-Neto, George A DosReis, Marise P Nunes, Célio G Freire-de-Lima
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90582 (2014)
Neutrophils are involved in the initial steps of most responses to pathogens and are essential components of the innate immune response. Due to the ability to produce and release various soluble mediators, neutrophils may participate in the regulatio
Externí odkaz:
https://doaj.org/article/a1829306f9524d2494694bcaadbe1c29
Publikováno v:
Mediators of Inflammation, Vol 2014 (2014)
Infection by Leishmania takes place in the context of inflammation and tissue repair. Besides tissue resident macrophages, inflammatory macrophages and neutrophils are recruited to the infection site and serve both as host cells and as effectors agai
Externí odkaz:
https://doaj.org/article/01d585c335ce451d989bcdcaf1750c9a
Autor:
Alessandra A Filardy, Ana Caroline Costa-da-Silva, Carolina M Koeller, Kamila Guimarães-Pinto, Flávia L Ribeiro-Gomes, Marcela F Lopes, Norton Heise, Célio G Freire-de-Lima, Marise P Nunes, George A DosReis
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85715 (2014)
We investigated early cellular responses induced by infection with Leishmania major in macrophages from resistant C57/BL6 mice. Infection increased production of reactive oxygen species by resident, but not inflammatory peritoneal macrophages. In add
Externí odkaz:
https://doaj.org/article/fc8120d2e8f447b49682c85d733b6aa5
Autor:
GEORGE A. DOSREIS
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 72, Iss 1, Pp 79-82 (2000)
Trypanosomatid protozoan parasites express an aggressive strategy of parasitism by infecting host macrophages and inducing extensive T-lymphocyte activation. One goal of such strategy is to drive the immune response of genetically susceptible hosts t
Externí odkaz:
https://doaj.org/article/c156a8dd9f414b639092a793ed5c945c