Zobrazeno 1 - 10
of 319
pro vyhledávání: '"George A, O'Toole"'
Autor:
Diksha Sharma, Vignesh Gokuladas Menon, Manasi Desai, Danielle Niu, Eleanor Bates, Annie Kandel, Erik R. Zinser, David M. Fields, George A. O’Toole, Mukul Sharma
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Marine microorganisms play a critical role in regulating atmospheric CO2 concentration via the biological carbon pump. Deposition of continental mineral dust on the sea surface increases carbon sequestration but the interaction between miner
Externí odkaz:
https://doaj.org/article/eb66410eaea84f2f9331e25465211c20
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 6 (2024)
ABSTRACT Swarming motility in pseudomonads typically requires both a functional flagellum and the production/secretion of a biosurfactant. Published work has shown that the wild-type Pseudomonas fluorescens Pf0-1 is swarming deficient due to a point
Externí odkaz:
https://doaj.org/article/5c7a9adef7d845cf8185d10901f43d05
Publikováno v:
mSphere, Vol 9, Iss 5 (2024)
ABSTRACT The genome of Pseudomonas fluorescens encodes >50 proteins predicted to play a role in bis-(3′-5′)-cyclic dimeric guanosine monophosphate (c-di-GMP)-mediated biofilm formation. We built a network representation of protein–protein inter
Externí odkaz:
https://doaj.org/article/4985ce3a11204bb498402cc9263a442f
Autor:
Jaime de Anda, Sherry L. Kuchma, Shanice S. Webster, Arman Boromand, Kimberley A. Lewis, Calvin K. Lee, Maria Contreras, Victor F. Medeiros Pereira, William Schmidt, Deborah A. Hogan, Corey S. O’Hern, George A. O’Toole, Gerard C. L. Wong
Publikováno v:
mBio, Vol 15, Iss 4 (2024)
ABSTRACTSwarming is a macroscopic phenomenon in which surface bacteria organize into a motile population. The flagellar motor that drives swarming in Pseudomonas aeruginosa is powered by stators MotAB and MotCD. Deletion of the MotCD stator eliminate
Externí odkaz:
https://doaj.org/article/391efbc41e544b3484677d31ac9c0f1a
Autor:
Liyun Wang, Yu-Chern Wong, Joshua M. Correira, Megan Wancura, Chris J. Geiger, Shanice S. Webster, Ahmed Touhami, Benjamin J. Butler, George A. O’Toole, Richard M. Langford, Katherine A. Brown, Berkin Dortdivanlioglu, Lauren Webb, Elizabeth Cosgriff-Hernandez, Vernita D. Gordon
Publikováno v:
npj Biofilms and Microbiomes, Vol 9, Iss 1, Pp 1-17 (2023)
Abstract Attachment of bacteria onto a surface, consequent signaling, and accumulation and growth of the surface-bound bacterial population are key initial steps in the formation of pathogenic biofilms. While recent reports have hinted that surface m
Externí odkaz:
https://doaj.org/article/881635b30da043f7bc70264bd4d6caae
Autor:
Courtney E. Price, Rebecca A. Valls, Alexis R. Ramsey, Nicole A. Loeven, Jane T. Jones, Kaitlyn E. Barrack, Joseph D. Schwartzman, Darlene B. Royce, Robert A. Cramer, Juliette C. Madan, Benjamin D. Ross, James Bliska, George A. O'Toole
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Persons with cystic fibrosis (CF), starting in early life, show intestinal microbiome dysbiosis characterized in part by a decreased relative abundance of the genus Bacteroides. Bacteroides is a major producer of the intestinal short chain f
Externí odkaz:
https://doaj.org/article/6a530a3789b44d7fa6ae1050050a8bac
Autor:
Koichi Sudo, Amber Delmas-Eliason, Shannon Soucy, Kaitlyn E. Barrack, Jiabao Liu, Akshaya Balasubramanian, Chengyi Jenny Shu, Michael J. James, Courtney L. Hegner, Henry D. Dionne, Alex Rodriguez-Palacios, Henry M. Krause, George A. O’Toole, Saul J. Karpen, Paul A. Dawson, Daniel Schultz, Mark S. Sundrud
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 18, Iss 6, Pp 101392- (2024)
Backgrounds & Aims: Bile acids (BAs) are core gastrointestinal metabolites with dual functions in lipid absorption and cell signaling. BAs circulate between the liver and distal small intestine (i.e., ileum), yet the dynamics through which complex BA
Externí odkaz:
https://doaj.org/article/4c920e38c9f24de48d0c7062be6a9281
Autor:
Christopher A. Kesthely, Rendi R. Rogers, Bassam El Hafi, Fabrice Jean-Pierre, George A. O’Toole
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 5 (2023)
ABSTRACT Bacterial infections in the lungs of persons with cystic fibrosis are typically composed of multispecies biofilm-like communities, which modulate clinically relevant phenotypes that cannot be explained in the context of a single species cult
Externí odkaz:
https://doaj.org/article/a9172d0144824873a50a92f17c59e5b4
Autor:
Courtney E. Price, Thomas H. Hampton, Rebecca A. Valls, Kaitlyn E. Barrack, George A. O’Toole, Juliette C. Madan, Modupe O. Coker
Publikováno v:
mSphere, Vol 8, Iss 4 (2023)
ABSTRACT Cystic fibrosis (CF) is a heritable disease that causes altered physiology at mucosal sites; these changes result in chronic infections in the lung, significant gastrointestinal complications as well as dysbiosis of the gut microbiome, altho
Externí odkaz:
https://doaj.org/article/aa0b0337d724452394ed04389ec97a6d
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Pseudomonas aeruginosa is an opportunistic pathogen that can establish acute and chronic infections in individuals who lack fully functional innate immunity. In particular, phagocytosis by neutrophils and macrophages is a key mechanism that
Externí odkaz:
https://doaj.org/article/bea31bb1a58a49f9aa4c892a4f6e7a69