Zobrazeno 1 - 10
of 23
pro vyhledávání: '"George A, Kosmiadi"'
Autor:
Alexander V. Panteleev, Irina Yu Nikitina, Irina A. Burmistrova, George A. Kosmiadi, Tatyana V. Radaeva, Rasul B. Amansahedov, Pavel V. Sadikov, Yana V. Serdyuk, Elena E. Larionova, Tatef R. Bagdasarian, Larisa N. Chernousova, Vitaly V. Ganusov, Irina V. Lyadova
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
It is generally thought that Mycobacterium tuberculosis (Mtb)-specific CD4+ Th1 cells producing IFN-γ are essential for protection against tuberculosis (TB). In some studies, protection has recently been associated with polyfunctional subpopulation
Externí odkaz:
https://doaj.org/article/cdecbc8bf74e45cb8984be6178d9687c
Autor:
Irina Yu Nikitina, Natalya A Kondratuk, George A Kosmiadi, Rasul B Amansahedov, Irina A Vasilyeva, Vitaly V Ganusov, Irina V Lyadova
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43733 (2012)
Effector CD4 T cells represent a key component of the host's anti-tuberculosis immune defense. Successful differentiation and functioning of effector lymphocytes protects the host against severe M. tuberculosis (Mtb) infection. On the other hand, eff
Externí odkaz:
https://doaj.org/article/ac7efb02161e404a844628d474c20afc
Autor:
Yana Serdyuk, Tatiana V. Radaeva, Irina V. Lyadova, Alexander A Nikolaev, George A. Kosmiadi, Lubov A. Gorelova, Irina Yu. Nikitina, Alexander V. Panteleev, Tatiana A. Nenasheva, Bozhenko Vk, Yana Yu. Kiseleva
Publikováno v:
The Journal of Immunology. 200:2090-2103
Th1 lymphocytes are considered the main mediators of protection against tuberculosis (TB); however, their phenotypic characteristics and relationship with Th17 and Th1Th17 populations during TB are poorly understood. We have analyzed Th1, Th17, and T
Autor:
Helmy Rachman, Nayoung Kim, Timo Ulrichs, Sven Baumann, Lydia Pradl, Ali Nasser Eddine, Matthias Bild, Marion Rother, Ralf-Jürgen Kuban, Jong Seok Lee, Robert Hurwitz, Volker Brinkmann, George A Kosmiadi, Stefan H E Kaufmann
Publikováno v:
PLoS ONE, Vol 1, p e29 (2006)
Apoptosis and activation of macrophages play an important role in the host response to mycobacterial infection involving TNF-alpha as a critical autocrine mediator. The underlying mechanisms are still ill-defined. Here, we demonstrate elevated levels
Externí odkaz:
https://doaj.org/article/5f8a0d7b31f94a7389283a431a7462cf
Autor:
Irina Yu, Nikitina, Alexander V, Panteleev, George A, Kosmiadi, Yana V, Serdyuk, Tatiana A, Nenasheva, Alexander A, Nikolaev, Lubov A, Gorelova, Tatiana V, Radaeva, Yana Yu, Kiseleva, Vladimir K, Bozhenko, Irina V, Lyadova
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 200(6)
Th1 lymphocytes are considered the main mediators of protection against tuberculosis (TB); however, their phenotypic characteristics and relationship with Th17 and Th1Th17 populations during TB are poorly understood. We have analyzed Th1, Th17, and T
Autor:
Pavel V. Sadikov, Irina A. Burmistrova, Irina Yu. Nikitina, Yana Serdyuk, Alexander V. Panteleev, Tatef R. Bagdasarian, Rasul B. Amansahedov, Larisa Chernousova, George A. Kosmiadi, Vitaly V. Ganusov, Tatyana V. Radaeva, Irina V. Lyadova, Elena Larionova
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 8 (2017)
Frontiers in Immunology, Vol 8 (2017)
It is generally thought that Mycobacterium tuberculosis (Mtb)-specific CD4+ Th1 cells producing IFN-γ are essential for protection against tuberculosis (TB). In some studies, protection has recently been associated with polyfunctional subpopulation
Autor:
Ulrike Zedler, María A. Duque-Correa, Peter J. Murray, Anja A. Kühl, Joseph E. Qualls, George A. Kosmiadi, Sandra Schommer-Leitner, Martin Rao, Stefan H. E. Kaufmann, Stephen T. Reece, January Weiner, Robert Hurwitz, Paulo C. Rodriguez
Publikováno v:
Proceedings of the National Academy of Sciences
Lung granulomas develop upon Mycobacterium tuberculosis (Mtb) infection as a hallmark of human tuberculosis (TB). They are structured aggregates consisting mainly of Mtb-infected and -uninfected macrophages and Mtb-specific T cells. The production of
Autor:
George A. Kosmiadi, Sabine Jörg, Pia Gamradt, Robert Hurwitz, Geraldine Nouailles, Stefanie Kuhlmann, Stephen T. Reece, Mischo Kursar, Hans-Joachim Mollenkopf, Marc Jacobsen, Stefan H. E. Kaufmann, Markus Koch, Delia Miekley, Tracey A. Day
Publikováno v:
European Journal of Immunology. 40:1663-1673
Tuberculosis causes 2 million deaths per year, yet in most cases the immune response successfully contains the infection and prevents disease outbreak. Induced lymphoid structures associated with pulmonary granuloma are observed during tuberculosis i
Autor:
Timo Ulrichs, George A. Kosmiadi, David Eisenberg, Johannes Schuchhardt, Leander Grode, Michael J. Strong, Stefan H. E. Kaufmann, Hans J. Mollenkopf, Helmy Rachman
Publikováno v:
Infection and Immunity. 74:1233-1242
Although tuberculosis remains a substantial global threat, the mechanisms that enable mycobacterial persistence and replication within the human host are ill defined. This study represents the first genome-wide expression analysis of Mycobacterium tu
Autor:
Sabine Jörg, Vladimir Mishenko, Timo Ulrichs, Lydia Pradl, George A. Kosmiadi, Nadya Gushina, Stefan H. E. Kaufmann, Marina Titukhina
Publikováno v:
The Journal of Infectious Diseases. 192:89-97
Background. In 90% of all cases, Mycobacterium tuberculosis infection results in latency rather than active disease, with the pathogen being contained within granulomatous lesions at the site of primary infection. Failure of this containment leads to