Výsledky vyhledávání - "George Zografi"

Considerations in the Development of Physically Stable High Drug Load API- Polymer Amorphous Solid Dispersions in the Glassy State

Autor: Ann, Newman, George, Zografi

Publikováno v: Journal of Pharmaceutical Sciences. 112:8-18

In this Commentary, the authors expand on their earlier studies of the solid-state long-term isothermal crystallization of amorphous API from the glassy state in amorphous solid dispersions, and focus on the effects of polymer concentration, and its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7984337873512bfa900dc023ad2cea0e
https://doi.org/10.1016/j.xphs.2022.08.007

Zobrazit plný text záznamu

Perspectives on the Wetting of Solids in Pharmaceutical Systems

Autor: Ann Newman, George Zografi

Publikováno v: Pharmaceutical Research.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::096e1d651f87eacda4cd29aadf9c425f
https://doi.org/10.1007/s11095-023-03491-3

Zobrazit plný text záznamu

What Are the Important Factors That Influence API Crystallization in Miscible Amorphous API-Excipient Mixtures during Long-Term Storage in the Glassy State?

Autor: Ann Newman, George Zografi

Publikováno v: Molecular pharmaceutics. 19(2)

In this Perspective, the authors examine the various factors that should be considered when attempting to use miscible amorphous API-excipient mixtures (amorphous solid dispersions and coamorphous systems) to prevent the solid-state crystallization o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b2da06c4dcc2679f59cfc9a3bfa1f0b
https://pubmed.ncbi.nlm.nih.gov/34378939

Zobrazit plný text záznamu

An Examination of Water Vapor Sorption by Multicomponent Crystalline and Amorphous Solids and Its Effects on Their Solid-State Properties

Autor: Ann Newman, George Zografi

Publikováno v: Journal of Pharmaceutical Sciences. 108:1061-1080

This commentary critically evaluated the unique effects of water vapor sorption by multicomponent solid forms of active pharmaceutical ingredients (APIs), and its effects on their physical and chemical properties. Such multicomponent forms include th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf04fab5b91854de969a886245c4eab
https://doi.org/10.1016/j.xphs.2018.10.038

Zobrazit plný text záznamu

What We Need to Know about Solid-State Isothermal Crystallization of Organic Molecules from the Amorphous State below the Glass Transition Temperature

Autor: Ann Newman, George Zografi

Publikováno v: Molecular pharmaceutics. 17(6)

In this Perspective, the authors have examined various principles associated with the isothermal crystallization of organic molecules from the amorphous state. The major objective was to better understand the underlying principles influencing long-te

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::066532cc4e4c3ece0277f354175dfab4
https://pubmed.ncbi.nlm.nih.gov/32275832

Zobrazit plný text záznamu

Commentary: Considerations in the Measurement of Glass Transition Temperatures of Pharmaceutical Amorphous Solids

Autor: Ann Newman, George Zografi

Publikováno v: AAPS PharmSciTech

An increased interest in using amorphous solid forms in pharmaceutical applications to increase solubility, dissolution, and bioavailability has generated a need for better characterization of key properties, such as the glass transition (Tg) tempera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31c13c8bed48031f71bf70e1ae434322
https://pubmed.ncbi.nlm.nih.gov/31848763

Zobrazit plný text záznamu

Elektronická kniha

Solid-State Properties of Pharmaceutical Materials

Autor: Stephen R. Byrn, George Zografi, Xiaoming (Sean) Chen

Presents a detailed discussion of important solid-state properties, methods, and applications of solid-state analysis Illustrates the various phases or forms that solids can assume and discussesvarious issues related to the relative stability of soli

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání