Zobrazeno 1 - 10
of 514
pro vyhledávání: '"George, du Toit"'
Autor:
Carolyn H. Baloh, MD, Noha Lim, Michelle Huffaker, Pooja Patel, Jody Tversky, George Du Toit, MB, BCh, Gideon Lack, MB, BCh, Tanya M. Laidlaw, Donald W. MacGlashan
Publikováno v:
World Allergy Organization Journal, Vol 17, Iss 8, Pp 100940- (2024)
Antigen-specific IgG2 and IgG3 are rarely measured in food allergy clinical trials despite known function in preventing mast cell and basophil activation. Our objective was to determine whether measuring peanut-specific IgG2 and IgG3 levels would cor
Externí odkaz:
https://doaj.org/article/ef11928c1bdf4be4a4603d24b9ca3e0f
Autor:
Rebecca C. Knibb, Lily Hawkins, Cassandra Screti, M. Hazel Gowland, Mamidipudi Thirumala Krishna, George du Toit, Christina J. Jones
Publikováno v:
Clinical and Translational Allergy, Vol 14, Iss 2, Pp n/a-n/a (2024)
Abstract Background Food hypersensitivity (FHS) management requires daily risk assessments of all food and drinks consumed to prevent unpleasant and potentially fatal adverse reactions. Most research has focussed on food allergy in children and famil
Externí odkaz:
https://doaj.org/article/8ba5b60c884540f2a96fb96cc46a2bee
Autor:
Katharina Blumchen, Andreas Kleinheinz, Ludger Klimek, Kirsten Beyer, Aikaterini Anagnostou, Christian Vogelberg, Sergejus Butovas, Robert Ryan, David Norval, Stefan Zeitler, George Du Toit
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 19, Iss 1, Pp 1-11 (2023)
Abstract Purpose Peanut allergy and its current management, involving peanut avoidance and use of rescue medication during instances of accidental exposure, are burdensome to patients and their caregivers and can be a source of stress, uncertainty, a
Externí odkaz:
https://doaj.org/article/d8d0d7fd76f3459cb961e76a1f5c79b0
Autor:
J. Andrew Bird, MD, Caroline Nilsson, MD, Kari Brown, MD, Trinh Pham, MS, Stephen Tilles, MD, George du Toit, MB, BCh, Amal Assa’ad, MD
Publikováno v:
Journal of Allergy and Clinical Immunology: Global, Vol 2, Iss 3, Pp 100120- (2023)
Background: Oral immunotherapy containing peanut (Arachis hypogaea) allergen powder-dnfp (PTAH) (Palforzia [Aimmune Therapeutics, Brisbane, Calif]) for 9 to 12 months resulted in higher tolerated amounts of peanut protein in PTAH-treated individuals
Externí odkaz:
https://doaj.org/article/880df47945f042aeb9a2cf79f96c1241
Autor:
Jay Portnoy, Christina E. Ciaccio, Janet Beausoleil, George Du Toit, Stanley Fineman, Stephen A. Tilles, June Zhang, Claire Lawrence, Mohamed Yassine, S Shahzad Mustafa
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 18, Iss 1, Pp 1-9 (2022)
Abstract Background Shared learnings from the early use of novel therapies can aid in their optimization. The recent introduction of peanut oral immunotherapy (peanut OIT; Palforzia [Peanut (Arachis hypogaea) Allergen Powder-dnfp]) for peanut allergy
Externí odkaz:
https://doaj.org/article/fe08691edeb945cfb62568c25f5d1212
Autor:
Benedetta Pessina, Mattia Giovannini, Francesca Mori, Giuseppe Di Cara, Elio Novembre, Susan Chan, Carsten Flohr, George du Toit
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/1f72ff1bf1f143a8b8f448846f0a39cc
Autor:
Kanika Kanchan, Gautam Shankar, Michelle F. Huffaker, Henry T. Bahnson, R Sharon Chinthrajah, Srinath Sanda, Monali Manohar, Hua Ling, Justin E. Paschall, George Du Toit, Ingo Ruczinski, Alkis Togias, Gideon Lack, Kari C. Nadeau, Stacie M. Jones, Gerald T. Nepom, Rasika A. Mathias
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
RationalePrevious studies identified an interaction between HLA and oral peanut exposure. HLA-DQA1*01:02 had a protective role with the induction of Ara h 2 epitope-specific IgG4 associated with peanut consumption during the LEAP clinical trial for p
Externí odkaz:
https://doaj.org/article/8558baf74a48493da4005046ba32951e
Autor:
Stephanie A. Leonard, Yasushi Ogawa, Paul T. Jedrzejewski, Soheila J. Maleki, Martin D. Chapman, Stephen A. Tilles, George Du Toit, S. Shahzad Mustafa, Brian P. Vickery
Publikováno v:
Frontiers in Allergy, Vol 3 (2022)
BackgroundImportant components of drug safety, efficacy, and acceptability involve manufacturing and testing of the drug substance and drug product. Peanut flour sourcing/processing and manufacturing processes may affect final drug product allergen p
Externí odkaz:
https://doaj.org/article/66b9658d81e64749b0fcdf9cea33ce93
Autor:
Francesco Pegoraro, Marzio Masini, Mattia Giovannini, Simona Barni, Francesca Mori, George du Toit, Irene Bartha, Enrico Lombardi
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/07906cc8d059439db3a640f1efe47cd9
Autor:
Margitta Worm, DucTung Nguyen, Russ Rackley, Antonella Muraro, George Du Toit, Tracey Lawrence, Hong Li, Kurt Brumbaugh, Magnus Wickman
Publikováno v:
Clinical and Translational Allergy, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Background Intramuscular (IM) injection of epinephrine (adrenaline) at the mid-anterolateral (AL) thigh is the international standard therapy for acute anaphylaxis. Concerns exist regarding implications of epinephrine auto-injector needles n
Externí odkaz:
https://doaj.org/article/706b9bee34a4432baf1fedace4238688