Cholesterol-containing lipid nanodiscs promote an α-synuclein binding mode that accelerates oligomerization

Autor: Jakubec, Martin, Bariås, Espen, Furse, Samuel Robert, Govasli Larsen, Morten Andreas, George, Vinnit, Turcu, Diana Cornelia, Iashchishyn, Igor A., Morozova-Roche, Ludmilla A., Halskau, Øyvind

Externí odkaz: https://hdl.handle.net/11250/2756380

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Cholesterol-containing lipid nanodiscs promote an α-synuclein binding mode that accelerates oligomerization.

Autor: Jakubec M; Department of Biological Sciences, University of Bergen, Norway.; Department of Molecular Biology, University of Bergen, Norway., Bariås E; Department of Biological Sciences, University of Bergen, Norway.; Department of Molecular Biology, University of Bergen, Norway., Furse S; Department of Molecular Biology, University of Bergen, Norway., Govasli ML; Department of Biological Sciences, University of Bergen, Norway.; Department of Molecular Biology, University of Bergen, Norway.; Division of Infection and Immunity, University College London, London, UK., George V; Department of Chemistry, University of Bergen, Norway., Turcu D; Department of Biological Sciences, University of Bergen, Norway.; Department of Molecular Biology, University of Bergen, Norway., Iashchishyn IA; Department of Medical Biochemistry and Biophysics, Umeå University, Sweden., Morozova-Roche LA; Department of Medical Biochemistry and Biophysics, Umeå University, Sweden., Halskau Ø; Department of Biological Sciences, University of Bergen, Norway.; Department of Molecular Biology, University of Bergen, Norway.

Publikováno v: The FEBS journal [FEBS J] 2021 Mar; Vol. 288 (6), pp. 1887-1905. Date of Electronic Publication: 2020 Sep 26.