Zobrazeno 1 - 10
of 28
pro vyhledávání: '"George, Thyphronitis"'
Autor:
Spyridoula Tsiomita, Effrosyni Maria Liveri, Panagiota Vardaka, Angeliki Vogiatzi, Argyris Skiadaresis, George Saridis, Ioannis Tsigkas, Theologos M Michaelidis, George Mavrothalassitis, George Thyphronitis
Publikováno v:
Journal of Leukocyte Biology. 112:641-657
Thymocyte differentiation and lineage commitment is regulated by an extensive network of transcription factors and signaling molecules among which Erk plays a central role. However, Erk effectors as well as the molecular mechanisms underlying this ne
Analysis of Protein Interaction Networks for the Detection of Candidate Hepatitis B and C Biomarkers
Publikováno v:
IEEE Journal of Biomedical and Health Informatics. 19:181-189
Hepatitis B virus (HBV) and hepatitis C virus (HCV) infection are the major causes of chronic liver disease, cirrhosis and hepatocellular carcinoma (HCC). The resolution or chronicity of acute infection is dependent on a complex interplay between vir
Autor:
George Thyphronitis, Urania Georgopoulou, Konstantina Katsarou, P.P. Doumba, Penelope Mavromara, Manousos M. Konstandoulakis, Pelagia Foka, John Koskinas, Panagiota Tsitoura, Elisavet Serti
Publikováno v:
Cellular and Molecular Life Sciences. 68:505-522
Hepatitis C virus (HCV) has been shown to actively replicate in cells of the immune system, altering both their function and cytokine expression. Naked nucleocapsids have been reported in the serum of infected patients. We investigated interference o
Autor:
George Dimitracopoulos, George Thyphronitis, Laura Virgilio, Fotini Paliogianni, Stavroula Boubali, Kassiani Liopeta, George Mavrothalassitis
Publikováno v:
Molecular Immunology. 46:345-354
Signal transduction by the cAMP/cAMP-dependent protein kinase A (PKA) pathway is triggered through multiple receptors and is important for many processes in a variety of cells. In T cells, the engagement of the TCR-CD3 complex induces CAMP, a second
Publikováno v:
bchm. 389:541-545
Type I interferons (IFNs) produced primarily by plasmacytoid dendritic cells (pDCs) as part of the innate immune response to infectious agents induce the maturation of myeloid DCs and enhance antigen presentation. Type I IFNs also enhance apoptosis o
Publikováno v:
Arthritis & Rheumatism. 46:215-222
Objective To identify genes that may participate in the pathophysiology of Sjogren's syndrome (SS), the technique of differential display was applied to labial minor salivary gland (MSG) biopsy samples. Methods Total RNA was isolated from MSG biopsy
Autor:
George Thyphronitis, Sylva Haralambous, Maria Evangelidou, Melina Markogiannaki, Michael G. Tovey, Nadia Kavrochorianou
Publikováno v:
Journal of leukocyte biology. 99(1)
Although interferon-β is used as first-line therapy for multiple sclerosis, the cell type-specific activity of type I interferons in multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis, remains obscure. In this study,
Publikováno v:
International Immunology. 9:523-531
Polarization of the immune response towards T(h)1 or T(h)2 profiles is under the control of several, not yet well known, mechanisms. The present study was undertaken to investigate whether immune responses generated against major protein antigens, of
Publikováno v:
BIBE
According to the World Health Organization hepatitis is a global threat to public health. Various statistics reveal that hundreds of millions of people worldwide are infected by chronic hepatitis C (HCV), which accounts for only the 15% of viral hepa
Autor:
George Thyphronitis, George Mavrothalassitis, Dimitrios T. Boumpas, Fotini Paliogianni, Nobuaki Hama
Publikováno v:
Cellular Immunology. 168:33-38
We have studied the signal requirements for human IL-4 promoter activation in Jurkat T cells by the use of DNA transfection assays with vectors carrying the IL-4 promoter linked to a reporter gene, Stimulation with calcium (Ca2+) ionophores (ionomyci