Zobrazeno 1 - 10
of 131
pro vyhledávání: '"George, Savulich"'
Autor:
David J. Whiteside, Negin Holland, Kamen A. Tsvetanov, Elijah Mak, Maura Malpetti, George Savulich, P. Simon Jones, Michelle Naessens, Matthew A. Rouse, Tim D. Fryer, Young T. Hong, Franklin I. Aigbirhio, Eoin Mulroy, Kailash P. Bhatia, Timothy Rittman, John T. O’Brien, James B. Rowe
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract There is extensive synaptic loss from frontotemporal lobar degeneration, in preclinical models and human in vivo and post mortem studies. Understanding the consequences of synaptic loss for network function is important to support translatio
Externí odkaz:
https://doaj.org/article/ab6733cf5df64638bd28121108e81c94
Autor:
Maura Malpetti, Negin Holland, P. Simon Jones, Rong Ye, Thomas E. Cope, Tim D. Fryer, Young T. Hong, George Savulich, Timothy Rittman, Luca Passamonti, Elijah Mak, Franklin I. Aigbirhio, John T. O’Brien, James B. Rowe
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 7, Pp 1515-1523 (2021)
Abstract Synaptic loss is an early and clinically relevant feature of many neurodegenerative diseases. Here we assess three adults at risk of frontotemporal dementia from C9orf72 mutation, using [11C]UCB‐J PET to quantify synaptic density in compar
Externí odkaz:
https://doaj.org/article/28737b54cd6649fbb8471e172f44ff20
Autor:
Nicolas Nicastro, Negin Holland, George Savulich, Stephen F. Carter, Elijah Mak, Young T. Hong, Selena Milicevic Sephton, Tim D. Fryer, Franklin I. Aigbirhio, James B. Rowe, John T. O’Brien
Publikováno v:
European Journal of Hybrid Imaging, Vol 4, Iss 1, Pp 1-7 (2020)
Abstract Objective Dementia with Lewy bodies (DLB) is a common cause of dementia, but atrophy is mild compared to Alzheimer’s disease. We propose that DLB is associated instead with severe synaptic loss, and we test this hypothesis in vivo using po
Externí odkaz:
https://doaj.org/article/635372aa80de47148e5ac5852312c09b
Autor:
Roxanne W. Hook, Masanori Isobe, George Savulich, Jon E. Grant, Konstantinos Ioannidis, David Christmas, Barbara J. Sahakian, Trevor W. Robbins, Samuel R. Chamberlain
Publikováno v:
European Neuropsychopharmacology, 71, 55-64. Elsevier
The role of the adenosine neurochemical system in human cognition is under-studied, despite such receptors being distributed throughout the brain. The aim of this study was to shed light on the role of the adenosine A2A receptors in human cognition u
Publikováno v:
Psychological Medicine. :1-4
Autor:
George Savulich, Owen Bowden-Jones, Robert Stephenson, Annette B. Brühl, Karen D. Ersche, Trevor W. Robbins, Barbara J. Sahakian
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
Novel psychoactive substances (NPS) are popular “club/party” drugs that first attracted attention in the UK in 2009 and remained legal until the 2016 Psychoactive Substances Act criminalized their distribution. Unlike “traditional” illicit dr
Externí odkaz:
https://doaj.org/article/823705e8670e45d5b1a41d926e0f579b
Autor:
Maura Malpetti, P. Simon Jones, Thomas E. Cope, Negin Holland, Michelle Naessens, Matthew A. Rouse, Timothy Rittman, George Savulich, David J. Whiteside, Duncan Street, Tim D. Fryer, Young T. Hong, Selena Milicevic Sephton, Franklin I. Aigbirhio, John T. O′Brien, James B. Rowe
Publikováno v:
Annals of Neurology. 93:142-154
Autor:
Audrey Low, Elijah Mak, James D. Stefaniak, Maura Malpetti, Nicolas Nicastro, George Savulich, Leonidas Chouliaras, Hugh S. Markus, James B. Rowe, John T. O’Brien
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
BackgroundThe peak width of skeletonized mean diffusivity (PSMD) has been proposed as a fully automated imaging marker of relevance to cerebral small vessel disease (SVD). We assessed PSMD in relation to conventional SVD markers, global measures of n
Externí odkaz:
https://doaj.org/article/c6db892f90a548be873e9c7ed014c661
Autor:
Negin Holland, P. Simon Jones, George Savulich, Michelle Naessens, Maura Malpetti, David J. Whiteside, Duncan Street, Peter Swann, Young T. Hong, Tim D. Fryer, Timothy Rittman, Eoin Mulroy, Franklin I. Aigbirhio, Kailash P. Bhatia, John T. O'Brien, James B. Rowe
Publikováno v:
Movement Disorders.
Autor:
George Savulich, Emily Thorp, Thomas Piercy, Katie A. Peterson, John D. Pickard, Barbara J. Sahakian
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 13 (2019)
Work and study increasingly rely on the use of technologies requiring individuals to switch attention rapidly between emails, texts and tasks. This has led to healthy people having problems of attention and concentration and difficulties getting into
Externí odkaz:
https://doaj.org/article/8c219e2cb6134f8abddde4c2b234cb99