Zobrazeno 1 - 10
of 61
pro vyhledávání: '"George, Sandusky"'
Autor:
Rula Atwani, Rohit Pravin Nagare, Amber Rogers, Mayuri Prasad, Virginie Lazar, George Sandusky, Yan Tong, Fabrizio Pin, Salvatore Condello
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-20 (2024)
Abstract Background Platinum-based chemotherapy regimens are a mainstay in the management of ovarian cancer (OC), but emergence of chemoresistance poses a significant clinical challenge. The persistence of ovarian cancer stem cells (OCSCs) at the end
Externí odkaz:
https://doaj.org/article/61ab184379fa418987004cdab1fef9ee
Autor:
Brijesh Kumar, Aditi S. Khatpe, Jiang Guanglong, Katie Batic, Poornima Bhat-Nakshatri, Maggie M. Granatir, Rebekah Joann Addison, Megan Szymanski, Lee Ann Baldridge, Constance J. Temm, George Sandusky, Sandra K. Althouse, Michele L. Cote, Kathy D. Miller, Anna Maria Storniolo, Harikrishna Nakshatri
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract The biologic basis of genetic ancestry-dependent variability in disease incidence and outcome is just beginning to be explored. We recently reported enrichment of a population of ZEB1-expressing cells located adjacent to ductal epithelial ce
Externí odkaz:
https://doaj.org/article/75421f2ad75f4636aa0061e39d6146f1
Autor:
Natascia Marino, Rana German, Xi Rao, Ed Simpson, Sheng Liu, Jun Wan, Yunlong Liu, George Sandusky, Max Jacobsen, Miranda Stovall, Sha Cao, Anna Maria V. Storniolo
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/127cae61a9764ee8bb39113ee5efd650
Autor:
Rula Atwani, Rohit Pravin Nagare, Amber Rogers, Mayuri Prasad, Virginie Lazar, George Sandusky, Yan Tong, Fabrizio Pin, Salvatore Condello
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/5c560b7da6f24cf3b90118ef19e01fd7
Autor:
Lakshmi Reddy Palam, Baskar Ramdas, Katelyn Pickerell, Santhosh Kumar Pasupuleti, Rahul Kanumuri, Annamaria Cesarano, Megan Szymanski, Bryce Selman, Utpal P. Dave, George Sandusky, Fabiana Perna, Sophie Paczesny, Reuben Kapur
Publikováno v:
JCI Insight, Vol 8, Iss 9 (2023)
Loss-of-function mutations in the DNA methyltransferase 3A (DNMT3A) are seen in a large number of patients with acute myeloid leukemia (AML) with normal cytogenetics and are frequently associated with poor prognosis. DNMT3A mutations are an early pre
Externí odkaz:
https://doaj.org/article/ec0e132ad5ae448a979e9b996e562b3e
Autor:
Silpa Gampala, Fenil Shah, Xiaoyu Lu, Hye-ran Moon, Olivia Babb, Nikkitha Umesh Ganesh, George Sandusky, Emily Hulsey, Lee Armstrong, Amber L. Mosely, Bumsoo Han, Mircea Ivan, Jing-Ruey Joanna Yeh, Mark R. Kelley, Chi Zhang, Melissa L. Fishel
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-24 (2021)
Abstract Background Pancreatic cancer is a complex disease with a desmoplastic stroma, extreme hypoxia, and inherent resistance to therapy. Understanding the signaling and adaptive response of such an aggressive cancer is key to making advances in th
Externí odkaz:
https://doaj.org/article/751a9e3c189b45859ea1d97745ceb7f8
Autor:
Ruizhong Wang, Brijesh Kumar, Poornima Bhat‐Nakshatri, Mayuri S. Prasad, Max H. Jacobsen, Gabriela Ovalle, Calli Maguire, George Sandusky, Trupti Trivedi, Khalid S. Mohammad, Theresa Guise, Narsimha R. Penthala, Peter A. Crooks, Jianguo Liu, Teresa Zimmers, Harikrishna Nakshatri
Publikováno v:
JCSM Rapid Communications, Vol 4, Iss 1, Pp 24-39 (2021)
Abstract Background Loss of skeletal muscle volume and functional limitations are poor prognostic markers in breast cancer patients. Several molecular defects in skeletal muscle including reduced myoblast determination protein 1 (MyoD) levels and inc
Externí odkaz:
https://doaj.org/article/a00e580af8d34f4daa2fee42e2201e27
Autor:
Aditi S. Khatpe, Rebecca Dirks, Poornima Bhat-Nakshatri, Henry Mang, Katie Batic, Sarah Swiezy, Jacob Olson, Xi Rao, Yue Wang, Hiromi Tanaka, Sheng Liu, Jun Wan, Duojiao Chen, Yunlong Liu, Fang Fang, Sandra Althouse, Emily Hulsey, Maggie M. Granatir, Rebekah Addison, Constance J. Temm, George Sandusky, Audrey Lee-Gosselin, Kenneth Nephew, Kathy D. Miller, Harikrishna Nakshatri
Publikováno v:
Cancer Research. 83:1345-1360
Study of genomic aberrations leading to immortalization of epithelial cells has been technically challenging due to the lack of isogenic models. To address this, we used healthy primary breast luminal epithelial cells of different genetic ancestry an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d80bdbe8f7e3fd859b87ba6cb6728f30
https://doi.org/10.1158/0008-5472.can-22-3667
https://doi.org/10.1158/0008-5472.can-22-3667
Autor:
Brijesh Kumar, Katie Batic, Poornima Bhat-Nakshatri, Maggie Granatir, Rebekah Addison, Megan Szymanski, Lee Ann Baldridge, Constance Temm, George Sandusky, Sandra Althouse, Anna Maria Storniolo, Harikrishna Nakshatri
Publikováno v:
Cancer Research. 83:P2-26
The biologic basis of genetic ancestry-dependent variability in disease incidence and outcome is just beginning to be explored. We recently reported enrichment of a population of ZEB1-expressing cells located adjacent to the ductal epithelial cells i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8ea1b1476e1debcdc6c7d05ca39d6c3
https://doi.org/10.1158/1538-7445.sabcs22-p2-26-08
https://doi.org/10.1158/1538-7445.sabcs22-p2-26-08
Publikováno v:
Forensic Medicine and Anatomy Research. 11:30-37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95dfd4fa174a535d101718e714f25756
https://doi.org/10.4236/fmar.2023.112003
https://doi.org/10.4236/fmar.2023.112003