Zobrazeno 1 - 10
of 43
pro vyhledávání: '"George, Kouvatseas"'
Autor:
Angelos Koutras, Georgios Lazaridis, Georgia-Angeliki Koliou, George Kouvatseas, Christos Christodoulou, Dimitrios Pectasides, Vassiliki Kotoula, Anna Batistatou, Mattheos Bobos, Eleftheria Tsolaki, Kyriaki Papadopoulou, George Pentheroudakis, Pavlos Papakostas, Stavroula Pervana, Kalliopi Petraki, Sofia Chrisafi, Evangelia Razis, Amanda Psyrri, Dimitrios Bafaloukos, Konstantine T Kalogeras, Haralambos P Kalofonos, George Fountzilas
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0207707 (2018)
In the current study, we performed a complete analysis, with four different methods, of all four HER family receptors, in a series of patients with metastatic breast cancer treated with trastuzumab-based regimens and evaluated their prognostic value.
Externí odkaz:
https://doaj.org/article/02859fb3024e4a0f9a806df523249868
Autor:
Flora Zagouri, Vassiliki Kotoula, George Kouvatseas, Maria Sotiropoulou, Triantafyllia Koletsa, Theofani Gavressea, Christos Valavanis, Helen Trihia, Mattheos Bobos, Georgios Lazaridis, Angelos Koutras, George Pentheroudakis, Pantelis Skarlos, Dimitrios Bafaloukos, Niki Arnogiannaki, Sofia Chrisafi, Christos Christodoulou, Pavlos Papakostas, Gerasimos Aravantinos, Paris Kosmidis, Charisios Karanikiotis, George Zografos, Christos Papadimitriou, George Fountzilas
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0180489 (2017)
To evaluate the prognostic role of elaborate molecular clusters encompassing cyclin D1, cyclin E1, p21, p27 and p53 in the context of various breast cancer subtypes.Cyclin E1, cyclin D1, p53, p21 and p27 were evaluated with immunohistochemistry in 10
Externí odkaz:
https://doaj.org/article/442358f042b046048f2e20f9815cc4d0
Autor:
Petros, Georgopoulos, Maria, Papaioannou, Soultana, Markopoulou, Aikaterini, Fragou, George, Kouvatseas, Apostolos, Apostolidis
Publikováno v:
Urology journal. 19(3)
Several studies have shown frequent changes in DNA methylation in bladder cancer (BCa), which vary among different geographical areas. The aim of this study is to examine the diagnostic accuracy of a panel of DNA methylation biomarkers in a Greek cli
Autor:
Kotoula, Ioannis Efstratiou, E Res, Sofia Lampaki, Paris Kosmidis, Despoina Televantou, Kyriaki Papadopoulou, G. Fountzilas, Emily Daskalaki, X. Mavropoulou, Grigorios Rallis, H. Linardou, Karavasilis, Samantas E, Anna Kalogera-Fountzila, Dimitrios Pectasides, Kostas N. Syrigos, George Kouvatseas, Thomas Zaramboukas, Mountzios G
Publikováno v:
Cancer Genomics - Proteomics. 16:531-541
Background/Aim: KRAS mutations are reported in 20-25% of non-small cell lung cancer (NSCLC) and their prognostic role is unclear. We studied KRAS and EGFR genotyping in Greek NSCLC patients. Patients and Methods: KRAS and EGFR genotypes were centrall
Autor:
Giannis Mountzios, Dimitra Aivazi, Ioannis Kostopoulos, Helen P Kourea, George Kouvatseas, Eleni Timotheadou, Pantelis Zebekakis, Ioannis Efstratiou, Helen Gogas, Chrisanthi Vamvouka, Sofia Chrisafi, Anastasios Stofas, George Pentheroudakis, Angelos Koutras, Eleni Galani, Dimitrios Bafaloukos, George Fountzilas
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91407 (2014)
INTRODUCTION: We sought to determine the level of protein expression of the critical components of the insulin-like growth factor receptor (IGFR) pathway and to evaluate their prognostic significance across the different early breast cancer subtypes.
Externí odkaz:
https://doaj.org/article/652f33702e93467f811acf194f56503f
Autor:
Petros Georgopoulos, Maria Papaioannou, Soultana Markopoulou, Aikaterini Fragou, George Kouvatseas, Apostolos Apostolidis
PurposeThe aim of this study was to explore the diagnostic potential of a panel of five hypermethylated gene promoters in bladder cancer. Individuals with primary BCa and control individuals matching the gender, age and smoking status of the cancer p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2eee69464bd8283065d4c3e881983789
https://doi.org/10.21203/rs.3.rs-153535/v1
https://doi.org/10.21203/rs.3.rs-153535/v1
Autor:
George Fountzilas, Vassiliki Kotoula, Dimitrios Pectasides, George Kouvatseas, Eleni Timotheadou, Mattheos Bobos, Xanthipi Mavropoulou, Christos Papadimitriou, Eleni Vrettou, Georgia Raptou, Angelos Koutras, Evangelia Razis, Dimitrios Bafaloukos, Epaminontas Samantas, George Pentheroudakis, Dimosthenis V Skarlos
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69256 (2013)
To explore the activity and safety of two schedules of ixabepilone, as first line chemotherapy, in patients with metastatic breast cancer previously treated with adjuvant chemotherapy, a randomized non-comparative phase II study was conducted. From N
Externí odkaz:
https://doaj.org/article/f6f0fb98581f4d6290390420788ff9a3
Autor:
Vasiliki Kotoula, Dimitris Bafaloukos, Kyriaki Papadopoulou, Pavlos Papakostas, Kalliopi Petraki, C. Christodoulou, Anna Batistatou, Georgios Pentheroudakis, Eleftheria Tsolaki, Mattheos Bobos, D.G. Pectasides, Sofia Chrisafi, George Kouvatseas, E. Razis, S. Pervana, Angelos Koutras, A. Psyrri, Konstantine T. Kalogeras, G-A Koliou, G. Fountzilas, Haralabos P. Kalofonos
Publikováno v:
Cancer Research. 78:P1-07
Background-aim: Metastatic breast cancer (MBC) is an incurable disease. Trastuzumab, a recombinant humanized monoclonal antibody, was found to significantly prolongsurvival of patients with metastatic HER2 over-expressing and/or amplified breast canc
Autor:
Georgios Pentheroudakis, Flora Zagouri, George Kouvatseas, Ioannis Tikas, Eleftheria Tsolaki, Dimitrios Pectasides, Pavlos Papakostas, Christos Christodoulou, Angelos Koutras, Mattheos Bobos, G. Fountzilas, PA Kosmidis, Elpida Charalambous, Georgios Lazaridis, Vasiliki Kotoula, Eleni Giannoulatou, Ioannis Efstratiou
Publikováno v:
Cancer Research. 77:P6-09
Background-aim: HER2-positive breast cancer (BC) features high rates of tumor infiltrating lymphocytes (TILs) and mutations (mut) in various genes, more frequently in TP53. We investigated associations between TILs and mutations in HER2-positive BC a
Autor:
Grigorios Rallis, Christos N. Papandreou, George Fountzilas, Evangelia Razis, Epaminontas Samantas, Kalliopi Varaki, Christos Christodoulou, Konstantine T. Kalogeras, Mattheos Bobos, Konstantinos N. Syrigos, Anna Kalogera-Fountzila, Vasilios Karavasilis, Athina Goudopoulou, Georgios C. Papadopoulos, George Kouvatseas
Publikováno v:
Journal of neuro-oncology. 134(2)
Small molecules, mainly tyrosine kinase inhibitors, are currently used in various malignancies. Lapatinib, a dual inhibitor of EGFR/HER2 tyrosine kinases, has demonstrated effectiveness in brain metastases from HER2-overexpressing breast cancer. It a