Zobrazeno 1 - 10
of 8 193
pro vyhledávání: '"George, Just"'
Autor:
Alastair J. Hayes, Xiaozhong Zheng, James O’Kelly, Lucile P.A. Neyton, Natalia A. Bochkina, Iain Uings, John Liddle, J. Kenneth Baillie, George Just, Margaret Binnie, Natalie Z.M. Homer, Toby B.J. Murray, James Baily, Kris McGuire, Christos Skouras, O. James Garden, Scott P. Webster, John P. Iredale, Sarah E.M. Howie, Damian J. Mole
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112763- (2023)
Summary: Kynurenine monooxygenase (KMO) blockade protects against multiple organ failure caused by acute pancreatitis (AP), but the link between KMO and systemic inflammation has eluded discovery until now. Here, we show that the KMO product 3-hydrox
Externí odkaz:
https://doaj.org/article/60fcd40d031a4ce4a162a97e4de568a3
Publikováno v:
Perfusion. 34:392-398
Background:Administering isoflurane 2.5% into the oxygenator during cardiopulmonary bypass results in no patient movement. However, doing so may result in an excessive depth of anaesthesia particularly, when hypothermia is induced. Bispectral index a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dfa0b833e2e7aaffe0e7266cf84d55a
https://doi.org/10.1177/0267659118822946
https://doi.org/10.1177/0267659118822946
Autor:
Robert M. Gifford, George Just, Patricia Lee, Joanna Simpson, Rebecca M. Reynolds, Scott Denham, Jennifer Richardson, Ruth Andrew, Catriona Kyle, Natalie Z.M. Homer
Steroid analysis is important in the clinical assessment of endocrine function in health and disease. Although tandem mass spectrometry methods coupled with chromatographic separation are considered the gold standard analytical technique in this sett
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a384ff1133a418160dfbebbf40b851
Publikováno v:
Journal of Cardiothoracic and Vascular Anesthesia. 31:2035-2041
Objective Volatile anesthetic agents such as isoflurane may be associated with fewer adverse myocardial events compared with total intravenous anesthesia in cardiac surgery. The authors aimed to determine whether reasonable isoflurane concentrations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b2563696648a353cc7d1eec4e1610c3
https://doi.org/10.1053/j.jvca.2017.03.014
https://doi.org/10.1053/j.jvca.2017.03.014
Publikováno v:
Perfusion. 33:148-155
Introduction: Bispectral index (BIS) and monitoring of end-tidal concentration may be associated with a reduction in the incidence of awareness during volatile-based general anaesthesia. An analogue of end-tidal concentration during cardiopulmonary b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::204a31abda9e63439f4b2ea8643f6f91
https://doi.org/10.1177/0267659117735883
https://doi.org/10.1177/0267659117735883
Autor:
Karen E. Chapman, Mark Nixon, Manu Verma, Karen Sooy, Natalie Z.M. Homer, Ruth Morgan, George Just, Ruth Andrew
Publikováno v:
Verma, M, Sooy, K, Just, G, Nixon, M, Morgan, R, Andrew, R, Chapman, K & Homer, N 2019, ' Quantitative analysis of 11-dehydrocorticosterone and corticosterone for preclinical studies by liquid chromatography triple quadrupole mass spectrometry ', Rapid communications in mass spectrometry . https://doi.org/10.1002/rcm.8610
Rapid Communications in Mass Spectrometry
Rapid Communications in Mass Spectrometry
Rationale The activity of the glucocorticoid activating enzyme 11β-hydroxysteroid dehydrogenase type-1 (11βHSD1) is altered in diseases such as obesity, inflammation and psychiatric disorders. In rodents 11βHSD1 converts inert 11-dehydrocorticoste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1601a4f78284b33574363fc769359be
https://hdl.handle.net/20.500.11820/284ffa6d-8d03-4e28-80d3-9874351b4433
https://hdl.handle.net/20.500.11820/284ffa6d-8d03-4e28-80d3-9874351b4433
Autor:
Karen E. Chapman, Carmel M. Moran, Adrian Garcia-Burgos, Paula J. Brunton, Natalie Z.M. Homer, Emma J Agnew, Hermes Manos, Karen Sooy, Adrian Thomson, George Just, Rachel V. Richardson, Gillian A. Gray
Publikováno v:
The Journal of Endocrinology
Agnew, E, Garcia-Burgos, A, Richardson, R, Manos, H, Thomson, A, Sooy, K, Just, G, Homer, N, Moran, C, Brunton, P J, Gray, G A & Chapman, K 2019, ' Antenatal dexamethasone treatment transiently alters diastolic function in the mouse fetal heart ', Journal of Endocrinology . https://doi.org/10.1530/JOE-18-0666
Agnew, E, Garcia-Burgos, A, Richardson, R, Manos, H, Thomson, A, Sooy, K, Just, G, Homer, N, Moran, C, Brunton, P J, Gray, G A & Chapman, K 2019, ' Antenatal dexamethasone treatment transiently alters diastolic function in the mouse fetal heart ', Journal of Endocrinology . https://doi.org/10.1530/JOE-18-0666
Endogenous glucocorticoid action is important in the structural and functional maturation of the fetal heart. In fetal mice, although glucocorticoid concentrations are extremely low before E14.5, glucocorticoid receptor (GR) is expressed in the heart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c890b5872d50a603eaac5943113c1f6f
https://pubmed.ncbi.nlm.nih.gov/31013474
https://pubmed.ncbi.nlm.nih.gov/31013474