Zobrazeno 1 - 10
of 70
pro vyhledávání: '"George, Jallo"'
Autor:
Kandarp Joshi, Menglang Yuan, Keisuke Katsushima, Olivier Saulnier, Animesh Ray, Ernest Amankwah, Stacie Stapleton, George Jallo, Michael D. Taylor, Charles G. Eberhart, Ranjan J. Perera
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-14 (2024)
Abstract Medulloblastoma, the most common malignant pediatric brain tumor, is classified into four main molecular subgroups, but group 3 and group 4 tumors are difficult to subclassify and have a poor prognosis. Rapid point-of-care diagnostic and pro
Externí odkaz:
https://doaj.org/article/326f988b197f4347bf4fff9b3108c6a0
Autor:
Menglang Yuan, Iqbal Mahmud, Keisuke Katsushima, Kandarp Joshi, Olivier Saulnier, Rudramani Pokhrel, Bongyong Lee, Wathsala Liyanage, Haritha Kunhiraman, Stacie Stapleton, Ignacio Gonzalez-Gomez, Rangaramanujam M. Kannan, Tanja Eisemann, Elayaraja Kolanthai, Sudipta Seal, Timothy J. Garrett, Saed Abbasi, Kimberly Bockley, Justin Hanes, Prem Chapagain, George Jallo, Robert J. Wechsler-Reya, Michael D. Taylor, Charles G. Eberhart, Animesh Ray, Ranjan J. Perera
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-17 (2023)
Abstract The prognosis of childhood medulloblastoma (MB) is often poor, and it usually requires aggressive therapy that adversely affects quality of life. microRNA-211 (miR-211) was previously identified as an important regulator of cells that descen
Externí odkaz:
https://doaj.org/article/d02fc40d411f4baba42e490fbec01155
Autor:
Keisuke Katsushima, Kandarp Joshi, Menglang Yuan, Brigette Romero, Mona Batish, Stacie Stapleton, George Jallo, Elayaraja Kolanthai, Sudipta Seal, Olivier Saulnier, Michael D. Taylor, Robert J. Wechsler-Reya, Charles G. Eberhart, Ranjan J. Perera
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113938- (2024)
Summary: Recent studies suggest that long non-coding RNAs (lncRNAs) contribute to medulloblastoma (MB) formation and progression. We have identified an lncRNA, lnc-HLX-2-7, as a potential therapeutic target in group 3 (G3) MBs. lnc-HLX-2-7 RNA specif
Externí odkaz:
https://doaj.org/article/4f95873122404b64823c7c17eb939dbe
Autor:
Keisuke Katsushima, Rudramani Pokhrel, Iqbal Mahmud, Menglang Yuan, Rabi Murad, Prabin Baral, Rui Zhou, Prem Chapagain, Timothy Garrett, Stacie Stapleton, George Jallo, Chetan Bettegowda, Eric Raabe, Robert J. Wechsler-Reya, Charles G. Eberhart, Ranjan J. Perera
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-13 (2023)
Abstract Medulloblastoma (MB) develops through various genetic, epigenetic, and non-coding (nc) RNA-related mechanisms, but the roles played by ncRNAs, particularly circular RNAs (circRNAs), remain poorly defined. CircRNAs are increasingly recognized
Externí odkaz:
https://doaj.org/article/189686aa08f2466da897e79be7e129e1
Autor:
Bongyong Lee, Iqbal Mohamad, Rudramani Pokhrel, Rabi Murad, Menglang Yuan, Stacie Stapleton, Chetan Bettegowda, George Jallo, Charles G. Eberhart, Timothy Garrett, Ranjan J. Perera
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-14 (2022)
Abstract Medulloblastoma (MB) is the most common malignant brain tumor in children. There remains an unmet need for diagnostics to sensitively detect the disease, particularly recurrences. Cerebrospinal fluid (CSF) provides a window into the central
Externí odkaz:
https://doaj.org/article/85f890cb07c74220837525066f03f625
Autor:
Alfredo Conti, Marcello Magnani, Matteo Zoli, Ralf A. Kockro, Constantin Tuleasca, Simone Peschillo, Giuseppe Emmanuele Umana, Seow Wan Tew, George Jallo, Kanwaljeet Garg, Robert F. Spetzler, Jesus Lafuente, Bipin Chaurasia
Publikováno v:
Brain and Spine, Vol 3, Iss , Pp 101728- (2023)
Introduction: Social media have become ubiquitous and their role in medicine is quickly growing. They provide an open platform by which members share educational material, clinical experiences, and collaborate with educational equity. Research questi
Externí odkaz:
https://doaj.org/article/a40a8a878df840909aa99b6262b14e39
Autor:
Bongyong Lee, Iqbal Mahmud, Rudramani Pokhrel, Rabi Murad, Menglang Yuan, Stacie Stapleton, Chetan Bettegowda, George Jallo, Charles G. Eberhart, Timothy Garrett, Ranjan J. Perera
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/02d75e089e904310b2512598bd097041
Autor:
Eric W. Prince, Ros Whelan, David M. Mirsky, Nicholas Stence, Susan Staulcup, Paul Klimo, Richard C. E. Anderson, Toba N. Niazi, Gerald Grant, Mark Souweidane, James M. Johnston, Eric M. Jackson, David D. Limbrick, Amy Smith, Annie Drapeau, Joshua J. Chern, Lindsay Kilburn, Kevin Ginn, Robert Naftel, Roy Dudley, Elizabeth Tyler-Kabara, George Jallo, Michael H. Handler, Kenneth Jones, Andrew M. Donson, Nicholas K. Foreman, Todd C. Hankinson
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Deep learning (DL) is a widely applied mathematical modeling technique. Classically, DL models utilize large volumes of training data, which are not available in many healthcare contexts. For patients with brain tumors, non-invasive diagnosi
Externí odkaz:
https://doaj.org/article/48a196a679684d488c084efeeb434cda
Publikováno v:
Neurobiology of Disease, Vol 141, Iss , Pp 104873- (2020)
Medulloblastoma is the most common malignant pediatric brain tumor with high fatality rate. Recent large-scale studies utilizing genome-wide technologies have sub-grouped medulloblastomas into four major subgroups: wingless (WNT), sonic hedgehog (SHH
Externí odkaz:
https://doaj.org/article/d8fab1a824924526aa30afcd96dde7cf
Autor:
Andrew M. Hersh, Daniel Lubelski, Nicholas Theodore, Daniel M. Sciubba, George Jallo, Nir Shimony
Publikováno v:
Pediatric Neurosurgery.
Background: Incidental intradural tumors of the spine in the pediatric population are rare lesions whose management remains unclear. Surgeons must balance the risks of iatrogenic deficits and complications after surgical resection against the risks f