Zobrazeno 1 - 10
of 35
pro vyhledávání: '"George, Hodgson"'
Autor:
Maria Szaruga, Dino A. Janssen, Claudia de Miguel, George Hodgson, Agnieszka Fatalska, Aleksandra P. Pitera, Antonina Andreeva, Anne Bertolotti
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Phosphorylation of the translation initiation factor eIF2α to initiate the integrated stress response (ISR) is a vital signalling event. Protein kinases activating the ISR, including PERK and GCN2, have attracted considerable attention for
Externí odkaz:
https://doaj.org/article/34a2e780c65b42a681d5eaae6d4c444a
Publikováno v:
Open Biology, Vol 11, Iss 12 (2021)
Phosphorylation of the translation initiation factor eIF2α is a rapid and vital cellular defence against many forms of stress. In mammals, the levels of eIF2α phosphorylation are set through the antagonistic action of four protein kinases and two h
Externí odkaz:
https://doaj.org/article/2ebf25ba0e42406a8cb5e2913927c95c
Autor:
Edward J. Hennessy, Marianne Schimpl, Emma Rivers, Paul D. Smith, Elizabeth Hardaker, Ann T. Doherty, Nichola L. Davies, Jon Travers, Qianxiu Zhu, Beth Williamson, Graham Smith, Lorraine Mooney, Helen Musgrove, Kristin Goldberg, Muireann Coen, Anne-Laure Lainé, Xiefeng Jiang, Philip Hopcroft, Yuting Zheng, Robert I Troup, George Hodgson, Nicola Lindsay, Lindsay McMurray, Olga Collingwood, Stephen D. Wilkinson, Sharon Tentarelli, Guang He, Philip B. Rawlins, Roshini Markandu, Jon Winter-Holt, Josephine Walton, Ankur Karmokar, J. Willem M. Nissink, Yumeng Mao, Dejian Yang, Alexander Pflug, Gary Fairley, Scott Boyd, Cheng Wang, Anne Jackson, Martin R. Brown, William McCoull, Neville McLean, Venkatesh Pilla Reddy
Publikováno v:
Journal of Medicinal Chemistry. 64:13524-13539
Inhibition of Mer and Axl kinases has been implicated as a potential way to improve the efficacy of current immuno-oncology therapeutics by restoring the innate immune response in the tumor microenvironment. Highly selective dual Mer/Axl kinase inhib
Autor:
William, McCoull, Scott, Boyd, Martin R, Brown, Muireann, Coen, Olga, Collingwood, Nichola L, Davies, Ann, Doherty, Gary, Fairley, Kristin, Goldberg, Elizabeth, Hardaker, Guang, He, Edward J, Hennessy, Philip, Hopcroft, George, Hodgson, Anne, Jackson, Xiefeng, Jiang, Ankur, Karmokar, Anne-Laure, Lainé, Nicola, Lindsay, Yumeng, Mao, Roshini, Markandu, Lindsay, McMurray, Neville, McLean, Lorraine, Mooney, Helen, Musgrove, J Willem M, Nissink, Alexander, Pflug, Venkatesh Pilla, Reddy, Philip B, Rawlins, Emma, Rivers, Marianne, Schimpl, Graham F, Smith, Sharon, Tentarelli, Jon, Travers, Robert I, Troup, Josephine, Walton, Cheng, Wang, Stephen, Wilkinson, Beth, Williamson, Jon, Winter-Holt, Dejian, Yang, Yuting, Zheng, Qianxiu, Zhu, Paul D, Smith
Publikováno v:
Journal of medicinal chemistry. 64(18)
Inhibition of Mer and Axl kinases has been implicated as a potential way to improve the efficacy of current immuno-oncology therapeutics by restoring the innate immune response in the tumor microenvironment. Highly selective dual Mer/Axl kinase inhib
Autor:
Richard George Hodgson
Publikováno v:
Charles Sorel. Polygraphe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d55499d82e4377779ea064060fe95cba
https://doi.org/10.3917/herm.bury.2017.01.0023
https://doi.org/10.3917/herm.bury.2017.01.0023
Publikováno v:
Annals of the New York Academy of Sciences. 77:703-709
Publikováno v:
Blood. 100:854-861
In steady-state hematopoiesis, G-CSF (granulocyte-colony stimulating factor) regulates the level of neutrophils in the bone marrow and blood. In this study, we have exploited the availability of G-CSF–deficient mice to evaluate the role of G-CSF in
Publikováno v:
Blood. 95:3725-3733
Granulocyte colony-stimulating factor (G-CSF) is a glycoprotein believed to play an important role in regulating granulopoiesis both at steady state and during an “emergency” situation. Generation of G-CSF and G-CSF receptor–deficient mice by g
Autor:
Richard George Hodgson
Publikováno v:
Littératures classiques. 35:195-206
Hodgson Richard George. Délicatesse, justesse, politesse : qualités intellectuelles, morales et esthétiques dans les Maximes et les Réflexions diverses de La Rochefoucauld. In: Littératures classiques, n°35, janvier 1999. La Rochefoucauld, Maxi