Zobrazeno 1 - 10
of 80
pro vyhledávání: '"George, Falkay"'
Publikováno v:
Journal of Clinical Gastroenterology and Hepatology.
Background: The possible gastrointestinal effects of khat (Catha edulis) chewing still under debate. Some authors are on the opinion that khat has a gastric and/or duodenal ul-cerogenic effect, while others denies this effect. Considering the absolut
Publikováno v:
Molecular Reproduction and Development. 81:524-530
Summary Aquaporins (AQPs) are integral membrane channels responsible for the transport of water across a cell membrane. Based on reports that AQPs are present and accumulate in the female reproductive tract late in pregnancy, our aim was to study the
Autor:
Yang Chang Wu, Patrick Trouillas, George Falkay, Da Wei Chuang, Balázs Dankó, Ana Teresa Martins, Fang Rong Chang, Attila Hunyadi
Publikováno v:
Tetrahedron Letters. 54:6529-6532
Xanthine oxidase (XO) is a key enzyme in purine metabolism with an important role in various pathologies. Several flavonoids have been reported for their capacity to inhibit this enzyme, and, for these compounds, the ability to adopt a planar 3D stru
Publikováno v:
European Journal of Pharmacology. 714:96-104
The endogenous neuropeptide nociceptin/orphanin FQ, translated from the prepronociceptin gene, exerts a contraction-inhibitory effect on the rat uterus. As nocistatin has been reported to cause functional antagonism of the pro-nociceptive effects of
Publikováno v:
International Journal of Molecular Sciences; Volume 17; Issue 8; Pages: 1300
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 17, Iss 8, p 1300 (2016)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 17, Iss 8, p 1300 (2016)
Thirteen mammalian aquaporin (AQP) water channels are known, and few of them play a role in the mammalian reproductive system. In our earlier study, the predominance of AQP5 in the late-pregnant rat uterus was proven. Our current aim was to investiga
Autor:
Zsolt Kormányos, Judit Verli, Róbert Gáspár, Adrienn Seres, Anna Klukovits, Eszter Ducza, Judit Hajagos-Tóth, George Falkay
Publikováno v:
Journal of Obstetrics and Gynaecology Research. 39:31-39
Aims: Our aims were to examine the effects of a simultaneous stimulation of β2-adrenergic receptors and inhibition of uterine phosphodiesterases (PDE), in the pregnant rat uterus in vivo and on human uterine tissue in vitro. We also set out to measu
Autor:
Martin Frotscher, Sandrine Marchais-Oberwinkler, Ágnes Berényi, George Falkay, Renáta Minorics, István Zupkó, Rolf W. Hartmann, Imre Ocsovszki
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry. 28:695-703
Inhibition of the local formation of estrogens seems to be an attractive strategy for pharmacological intervention in hormone-dependent disorders. The direct antiproliferative properties of ten nonsteroidal 17β-hydroxysteroid dehydrogenase type 1 (1
Ontogeny of sulfonylurea-binding regulatory subunits of KATP channels in the pregnant rat myometrium
Publikováno v:
REPRODUCTION. 142:175-181
ATP-sensitive potassium channels (KATPchannels) are composed of sulfonylurea receptors (SURs) and potassium inward rectifiers (Kir6.x) that assemble to form a large octameric channel. This study was designed to examine the expression and role of sulf
Publikováno v:
Life Sciences. 87:733-737
Previous results by our group showed that the in vitro uterus-relaxing potency of β(2)-adrenergic receptor (β(2)-AR) agonists and uterine cAMP accumulation are enhanced in case of visceral inflammation. Our aim was to study the effects of the non-s
Autor:
George Falkay, Andrea Vasas, Aimun A. E. Ahmed, Árpád Márki, Judit Hohmann, Róbert Gáspár, Mahmoud Mudawi Eltahir Mudawi
Publikováno v:
American Journal of Biochemistry and Biotechnology. 6:231-238
Problem statement: The aim of this study is to investigate the pharmacological effects of the Methanolic-extract (AH2) of El-Hazha and its sub-fractions. Approach: These investigations were carried out on in vitro isolated uterus preparations from No