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of 5
pro vyhledávání: '"George, Dinos"'
Autor:
Artemis Tsirogianni, Nikolina Ntinou, Konstantina Karampatsou, George Dinos, Georgia G. Kournoutou, Constantinos M. Athanassopoulos
Publikováno v:
Molecules, Vol 29, Iss 17, p 4169 (2024)
Pactamycin (PCT), an antibiotic produced by Streptomyces pactum, is a five-membered ring aminocyclitol that is active against a variety of Gram-positive and Gram-negative microorganisms, as well as several animal tumor lines in culture and in vivo. P
Externí odkaz:
https://doaj.org/article/572e819f43e249958da866a576b61d73
Autor:
Artemis Tsirogianni, Georgia G. Kournoutou, Maria Mpogiatzoglou, George Dinos, Constantinos M. Athanassopoulos
Publikováno v:
Antibiotics, Vol 12, Iss 5, p 832 (2023)
In a previous study published by our group, successful modification of the antibiotic chloramphenicol (CHL) was reported, which was achieved by replacing the dichloroacetyl tail with alpha and beta amino acids, resulting in promising new antibacteria
Externí odkaz:
https://doaj.org/article/8a603ebaf91d4a0eb0c673c4fafce3ac
Autor:
Georgia G. Kournoutou, George Dinos
Publikováno v:
Antibiotics, Vol 11, Iss 8, p 1063 (2022)
Azithromycin has become famous in the last two years, not for its main antimicrobial effect, but for its potential use as a therapeutic agent for COVID-19 infection. Initially, there were some promising results that supported its use, but it has beco
Externí odkaz:
https://doaj.org/article/ba351f8744d144d7a809dd32ea457fb5
Autor:
Artemis Tsirogianni, Georgia G. Kournoutou, Anthony Bougas, Eleni Poulou-Sidiropoulou, George Dinos, Constantinos M. Athanassopoulos
Publikováno v:
Antibiotics, Vol 10, Iss 4, p 394 (2021)
To combat the dangerously increasing pathogenic resistance to antibiotics, we developed new pharmacophores by chemically modifying a known antibiotic, which remains to this day the most familiar and productive way for novel antibiotic development. We
Externí odkaz:
https://doaj.org/article/9597f02014bf476cb421d746648b1f10
Autor:
George, Dinos, Daniel N, Wilson, Yoshika, Teraoka, Witold, Szaflarski, Paola, Fucini, Dimitrios, Kalpaxis, Knud H, Nierhaus
Publikováno v:
Molecular cell. 13(1)
The crystal structures of the universal translation-initiation inhibitors edeine and pactamycin bound to ribosomal 30S subunit have revealed that edeine induces base pairing of G693:C795, residues that constitute the pactamycin binding site. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0aa3e31ea8157deff75558dd5d3434b4
https://pubmed.ncbi.nlm.nih.gov/14731399
https://pubmed.ncbi.nlm.nih.gov/14731399