Zobrazeno 1 - 2
of 2
pro vyhledávání: '"George, Derbin"'
Autor:
Jennifer Wang, David Trinkle, George Derbin, Kyle Martin, Shasad Sharif, Peter Timmins, Divyakant Desa
Publikováno v:
Journal of Excipients and Food Chemicals, Vol 5, Iss 1 (2016)
A bilayer tablet formulation approach was used to develop a fixed dose combination tablet formulation of drugs Y & Z. The weight of Layer I containing Drug Y and the weight of Layer II A or II B containing Drug Z were 250 mg and 1280 mg, respectively
Externí odkaz:
https://doaj.org/article/5eb7087bf7c14c2bbcef9ad49762969e
Autor:
Zhen-wei, Cai, Yongzheng, Zhang, Robert M, Borzilleri, Ligang, Qian, Stephanie, Barbosa, Donna, Wei, Xiaoping, Zheng, Lawrence, Wu, Junying, Fan, Zhongping, Shi, Barri S, Wautlet, Steve, Mortillo, Robert, Jeyaseelan, Daniel W, Kukral, Amrita, Kamath, Punit, Marathe, Celia, D'Arienzo, George, Derbin, Joel C, Barrish, Jeffrey A, Robl, John T, Hunt, Louis J, Lombardo, Joseph, Fargnoli, Rajeev S, Bhide
Publikováno v:
Journal of medicinal chemistry. 51(6)
A series of amino acid ester prodrugs of the dual VEGFR-2/FGFR-1 kinase inhibitor 1 (BMS-540215) was prepared in an effort to improve the aqueous solubility and oral bioavailability of the parent compound. These prodrugs were evaluated for their abil