Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Georg Zeller"'
Autor:
Maximilian Hohmann, Valentina Brunner, Widya Johannes, Dominik Schum, Laura M. Carroll, Tianzhe Liu, Daisuke Sasaki, Johanna Bosch, Thomas Clavel, Stephan A. Sieber, Georg Zeller, Markus Tschurtschenthaler, Klaus-Peter Janßen, Tobias A. M. Gulder
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract The gut microbiota influences human health and the development of chronic diseases. However, our understanding of potentially protective or harmful microbe-host interactions at the molecular level is still in its infancy. To gain further ins
Externí odkaz:
https://doaj.org/article/9dfc486a3c544c3f8858b03305338c9f
Autor:
Gaia Sambruni, Angeli D. Macandog, Jakob Wirbel, Danilo Cagnina, Carlotta Catozzi, Tiziano Dallavilla, Francesca Borgo, Nicola Fazio, Uberto Fumagalli-Romario, Wanda L. Petz, Teresa Manzo, Simona P. Ravenda, Georg Zeller, Luigi Nezi, Martin H. Schaefer
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-19 (2023)
Abstract Background The association between microbes and cancer has been reported repeatedly; however, it is not clear if molecular tumour properties are connected to specific microbial colonisation patterns. This is due mainly to the current technic
Externí odkaz:
https://doaj.org/article/213f6dde22fd4445b062116b7522266d
Autor:
Hans-Joachim Ruscheweyh, Alessio Milanese, Lucas Paoli, Nicolai Karcher, Quentin Clayssen, Marisa Isabell Keller, Jakob Wirbel, Peer Bork, Daniel R. Mende, Georg Zeller, Shinichi Sunagawa
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-12 (2022)
Abstract Background Taxonomic profiling is a fundamental task in microbiome research that aims to detect and quantify the relative abundance of microorganisms in biological samples. Available methods using shotgun metagenomic data generally depend on
Externí odkaz:
https://doaj.org/article/7dcca887fbe548e4aa354361f2fc4c09
Autor:
Anne Kerstin Thomann, Torsten Wüstenberg, Jakob Wirbel, Laura-Louise Knoedler, Philipp Arthur Thomann, Georg Zeller, Matthias Philip Ebert, Stefanie Lis, Wolfgang Reindl
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Extraintestinal symptoms are common in inflammatory bowel diseases (IBD) and include depression and fatigue. These are highly prevalent especially in active disease, potentially due to inflammation-mediated changes in the microbio
Externí odkaz:
https://doaj.org/article/e9aa2f81853c459da1350817e225802c
Autor:
Solomon A. Sowah, Alessio Milanese, Ruth Schübel, Jakob Wirbel, Ece Kartal, Theron S. Johnson, Frank Hirche, Mirja Grafetstätter, Tobias Nonnenmacher, Romy Kirsten, Marina López-Nogueroles, Agustín Lahoz, Kathrin V. Schwarz, Jürgen G. Okun, Cornelia M. Ulrich, Johanna Nattenmüller, Arnold von Eckardstein, Daniel Müller, Gabriele I. Stangl, Rudolf Kaaks, Tilman Kühn, Georg Zeller
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-21 (2022)
Abstract Background The gut microbiota has been suggested to play a significant role in the development of overweight and obesity. However, the effects of calorie restriction on gut microbiota of overweight and obese adults, especially over longer du
Externí odkaz:
https://doaj.org/article/b2a9d6f5ed5d4fb9a3a65f3eb76bef31
Autor:
Jakob Wirbel, Konrad Zych, Morgan Essex, Nicolai Karcher, Ece Kartal, Guillem Salazar, Peer Bork, Shinichi Sunagawa, Georg Zeller
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-27 (2021)
Abstract The human microbiome is increasingly mined for diagnostic and therapeutic biomarkers using machine learning (ML). However, metagenomics-specific software is scarce, and overoptimistic evaluation and limited cross-study generalization are pre
Externí odkaz:
https://doaj.org/article/95e2803d50604883abc56458a1115172
Autor:
Nicolai Karcher, Edoardo Pasolli, Francesco Asnicar, Kun D. Huang, Adrian Tett, Serena Manara, Federica Armanini, Debbie Bain, Sylvia H. Duncan, Petra Louis, Moreno Zolfo, Paolo Manghi, Mireia Valles-Colomer, Roberta Raffaetà, Omar Rota-Stabelli, Maria Carmen Collado, Georg Zeller, Daniel Falush, Frank Maixner, Alan W. Walker, Curtis Huttenhower, Nicola Segata
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-27 (2020)
Abstract Background Eubacterium rectale is one of the most prevalent human gut bacteria, but its diversity and population genetics are not well understood because large-scale whole-genome investigations of this microbe have not been carried out. Resu
Externí odkaz:
https://doaj.org/article/f32fcb210c9e4d5b862390f89e7cb781
Autor:
Daniel R. Garza, Rahwa Taddese, Jakob Wirbel, Georg Zeller, Annemarie Boleij, Martijn A. Huynen, Bas E. Dutilh
Publikováno v:
Cancer & Metabolism, Vol 8, Iss 1, Pp 1-13 (2020)
Abstract Background Colorectal cancer (CRC) is a complex multifactorial disease. Increasing evidence suggests that the microbiome is involved in different stages of CRC initiation and progression. Beyond specific pro-oncogenic mechanisms found in pat
Externí odkaz:
https://doaj.org/article/aa3e05f63aa2450ca7b2b371b6e0b5a5
Autor:
Isabel Moreno-Indias, Leo Lahti, Miroslava Nedyalkova, Ilze Elbere, Gennady Roshchupkin, Muhamed Adilovic, Onder Aydemir, Burcu Bakir-Gungor, Enrique Carrillo-de Santa Pau, Domenica D’Elia, Mahesh S. Desai, Laurent Falquet, Aycan Gundogdu, Karel Hron, Thomas Klammsteiner, Marta B. Lopes, Laura Judith Marcos-Zambrano, Cláudia Marques, Michael Mason, Patrick May, Lejla Pašić, Gianvito Pio, Sándor Pongor, Vasilis J. Promponas, Piotr Przymus, Julio Saez-Rodriguez, Alexia Sampri, Rajesh Shigdel, Blaz Stres, Ramona Suharoschi, Jaak Truu, Ciprian-Octavian Truică, Baiba Vilne, Dimitrios Vlachakis, Ercument Yilmaz, Georg Zeller, Aldert L. Zomer, David Gómez-Cabrero, Marcus J. Claesson
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The human microbiome has emerged as a central research topic in human biology and biomedicine. Current microbiome studies generate high-throughput omics data across different body sites, populations, and life stages. Many of the challenges in microbi
Externí odkaz:
https://doaj.org/article/58ddf268165e41df95208c7ec045cc9d
Autor:
Alessio Milanese, Daniel R Mende, Lucas Paoli, Guillem Salazar, Hans-Joachim Ruscheweyh, Miguelangel Cuenca, Pascal Hingamp, Renato Alves, Paul I Costea, Luis Pedro Coelho, Thomas S. B. Schmidt, Alexandre Almeida, Alex L Mitchell, Robert D. Finn, Jaime Huerta-Cepas, Peer Bork, Georg Zeller, Shinichi Sunagawa
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Metagenomic analysis based on universal phylogenetic marker gene (MG)-based operational taxonomic units (mOTUs) is a useful strategy, especially for microbial species without reference genomes. Here, the authors develop mOTUs2, an updated and functio
Externí odkaz:
https://doaj.org/article/a310312540d94a05b62a9e1f75202c64