Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Georg Vucak"'
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113583- (2023)
Summary: Selective autophagy mediates the removal of harmful material from the cytoplasm. This cargo material is selected by cargo receptors, which orchestrate its sequestration within double-membrane autophagosomes and subsequent lysosomal degradati
Externí odkaz:
https://doaj.org/article/ab634fcf79e74db9afc6897c181e658f
Autor:
Rainer Ettelt, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini
Lysosomes are highly dynamic organelles that regulate metabolic signaling pathways by recruiting cytosolic molecules to protein platforms on the lysosomal membrane. We performed a proximity-dependent labeling screen to identify novel proteins recruit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fc1426bafa24ed62c05d106004752ac
https://doi.org/10.1101/2023.02.01.526449
https://doi.org/10.1101/2023.02.01.526449
Publikováno v:
Biochemical Society Transactions. 45:27-36
The RAS/ERK pathway has been intensely studied for about three decades, not least because of its role in human pathologies. ERK activation is observed in the majority of human cancers; in about one-third of them, it is driven by mutational activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::311910668cbcaa28412c42b9934b2948
https://doi.org/10.1042/bst20160135
https://doi.org/10.1042/bst20160135
Publikováno v:
Biochemical Society transactions. 45(1)
The RAS/ERK pathway has been intensely studied for about three decades, not least because of its role in human pathologies. ERK activation is observed in the majority of human cancers; in about one-third of them, it is driven by mutational activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7e49c50487de7dfd8d00f829974ce077
https://pubmed.ncbi.nlm.nih.gov/28202657
https://pubmed.ncbi.nlm.nih.gov/28202657