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pro vyhledávání: '"Georg Topalov"'
Autor:
James D. Winkler, Susan L. Gloor, Michael J. Humphries, Walt E. DeWolf, Kelly Regal, Kevin Ronald Condroski, Greg Miknis, John Fischer, John A. Josey, Boys Mark Laurence, Mareli Rodriguez, Stefan Gross, Kevin Koch, Georg Topalov, Lisa DeMeese, John S. Zuzack, Rui Xu, Eli M. Wallace, Kristin Shotts, Brad Fell, Nicholas J. Raddatz
Publikováno v:
Cancer Research. 70:4484-4484
As a consequence of a variety of genetic lesions, the PI3K/Akt pathway is constitutively activated in a large proportion of human cancers. The mTOR kinase plays an important role in this pathway as the key component of two independent signaling compl