Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Georg Stussi"'
Autor:
Sofie Brouwers, Raphael Heimgartner, Natallia Laptseva, Adriano Aguzzi, Niklas F. Ehl, Thomas Fehr, Felicitas Hitz, Hans H. Jung, Joel Kälin, Markus G. Manz, Beat Müllhaupt, Frank Ruschitzka, Harald Seeger, Georg Stussi, Markus Zweier, Andreas J. Flammer, Bernhard Gerber, Rahel Schwotzer
Publikováno v:
Swiss Medical Weekly, Vol 154, Iss 2 (2024)
AIMS OF THE STUDY: Systemic amyloidoses are rare protein-folding diseases with heterogeneous, often nonspecific clinical presentations. To better understand systemic amyloidoses and to apply state-of-the-art diagnostic pathways and treatment, the int
Externí odkaz:
https://doaj.org/article/cf69857cee974352a0bcd0080184335f
Autor:
Jacobien R. Hilberink, Isabelle A. van Zeventer, Dana A. Chitu, Thomas Pabst, Saskia K. Klein, Georg Stussi, Laimonas Griskevicius, Peter J. M. Valk, Jacqueline Cloos, Arjan A. van de Loosdrecht, Dimitri Breems, Danielle van Lammeren-Venema, Rinske Boersma, Mojca Jongen-Lavrencic, Martin Fehr, Mels Hoogendoorn, Markus G. Manz, Maaike Söhne, Rien van Marwijk Kooy, Dries Deeren, Marjolein W. M. van der Poel, Marie Cecile Legdeur, Lidwine Tick, Yves Chalandon, Emanuele Ammatuna, Sabine Blum, Bob Löwenberg, Gert J. Ossenkoppele, Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON), Swiss Group for Clinical Cancer Research (SAKK), Gerwin Huls
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Treatment choice according to the individual conditions remains challenging, particularly in older patients with acute myeloid leukemia (AML) and high risk myelodysplastic syndrome (MDS). The impact of performance status, comorbidities, and
Externí odkaz:
https://doaj.org/article/71614de5d82b474e855269ada1ea2dee
Autor:
Corentin Orvain, Sylvain Chantepie, Xavier Thomas, Martine Escofrre-Barbe, Francoise Huguet, Yohan Desbrosses, Gaelle Guillerm, Madalina Uzunov, Thibaut Leguay, Sarah Barbieux, Norbert Vey, Patrice Chevallier, Jean-Valere Malfuson, Stephane Lepretre, Michael Baumann, Murat Aykut, Abdelaziz Chaib, Magalie Joris, Hacene Zerazhi, Georg Stussi, Jacques Chapiro, Celine Berthon, Caroline Bonmati, Eric Jourdan, Diana Carp, Amb roise Marcais, Maria-Pilar Gallego-Hernanz, Iona Vaida, Karin Bilger, Alban Villate, Florence Pasquier, Yves Chalandon, Sebastien Maury, Veronique Lheritier, Norbert Ifrah, Herve Dombret, Nicolas Boissel, Mathilde Hunault-Berger.
Publikováno v:
Haematologica, Vol 108, Iss 12 (2023)
Whereas the prognosis of adult patients with Philadelphia-negative acute lymphoblastic leukemia (ALL) has greatly improved since the advent of pediatric-inspired regimens, the impact of initial central nervous system (CNS) involvement has not been fo
Externí odkaz:
https://doaj.org/article/c059a6d68eb242c0a6943328399d181f
Autor:
Andrea Ruberti, Johanna A. Kremer Hovinga, Federico Nappi, Aurora Vettese, Elena Bianchi, Eliana Fernandes, Elena Galfetti, Rita Monotti, Pamella Paul, Stefano Regazzoni, Daniela Valente, Davide Rossi, Georg Stussi, Bernhard Gerber
Publikováno v:
Swiss Medical Weekly, Vol 153, Iss 3 (2023)
AIMS OF THE STUDY: Acquired haemophilia A is a rare disease with an annual incidence of 1.48 per million. Based on clinical observations, we suspect a higher incidence in southern Switzerland, and aimed at providing local epidemiological data, and cl
Externí odkaz:
https://doaj.org/article/b9cd8e6b1af4463c9eb5e55afec7ae86
Autor:
Alberto J. Arribas, Sara Napoli, Luciano Cascione, Giulio Sartori, Laura Barnabei, Eugenio Gaudio, Chiara Tarantelli, Afua Adjeiwaa Mensah, Filippo Spriano, Antonella Zucchetto, Francesca M Rossi, Andrea Rinaldi, Manuel Castro de Moura, Sandra Jovic, Roberta Bordone-Pittau, Alessandra Di Veroli, Anastasios Stathis, Gabriele Cruciani, Georg Stussi, Valter Gattei, Jennifer R. Brown, Manel Esteller, Emanuele Zucca, Davide Rossi, Francesco Bertoni
Publikováno v:
Haematologica, Vol 107, Iss 11 (2022)
PI3Kδ inhibitors are active in patients with lymphoid neoplasms and a first series of them have been approved for the treatment of multiple types of B-cell lymphoid tumors, including marginal zone lymphoma (MZL). The identification of the mechanisms
Externí odkaz:
https://doaj.org/article/1745563a44104ecc87ba453e796f4738
Autor:
Eugenio Gaudio, Chiara Tarantelli, Filippo Spriano, Francesca Guidetti, Giulio Sartori, Roberta Bordone, Alberto J. Arribas, Luciano Cascione, Mario Bigioni, Giuseppe Merlino, Alessio Fiascarelli, Alessandro Bressan, Afua Adjeiwaa Mensah, Gaetanina Golino, Renzo Lucchini, Elena Bernasconi, Davide Rossi, Emanuele Zucca, Georg Stussi, Anastasios Stathis, Robert S. Boyd, Rachel L. Dusek, Arnima Bisht, Nickolas Attanasio, Christian Rohlff, Andrea Pellacani, Monica Binaschi, Francesco Bertoni
Publikováno v:
Haematologica, Vol 105, Iss 11 (2020)
Antibody drug conjugates represent an important class of anti-cancer drugs in both solid tumors and hematological cancers. Here, we report preclinical data on the anti-tumor activity of the first-in-class antibody drug conjugate MEN1309/OBT076 target
Externí odkaz:
https://doaj.org/article/fd52bf5cbc7f444ba1538b1b0e104dc7
Autor:
Stuart W. Hicks, Chiara Tarantelli, Alan Wilhem, Eugenio Gaudio, Min Li, Alberto J. Arribas, Filippo Spriano, Roberta Bordone, Luciano Cascione, Katharine C. Lai, Qifeng Qiu, Monica Taborelli, Davide Rossi, Georg Stussi, Emanuele Zucca, Anastasios Stathis, Callum M. Sloss, Francesco Bertoni
Publikováno v:
Haematologica, Vol 104, Iss 8 (2019)
Antibody-drug conjugates (ADC) are a novel way to deliver potent cytotoxic compounds to cells expressing a specific antigen. Four ADC targeting CD19, including SAR3419 (coltuximab ravtansine), have entered clinical development. Here, we present huB4-
Externí odkaz:
https://doaj.org/article/1f3dab50ef484dd68bae9787aaa3453e
Autor:
Beatrice Drexler, Jakob R. Passweg, Alexandar Tzankov, Martin Bigler, Alexandre PA Theocharides, Nathan Cantoni, Peter Keller, Georg Stussi, Axel Ruefer, Rudolf Benz, Geneviève Favre, Pontus Lundberg, Ronny Nienhold, Andrea Fuhrer, Christine Biaggi, Markus G. Manz, Mario Bargetzi, Simon Mendez-Ferrer, Radek C. Skoda
Publikováno v:
Haematologica, Vol 104, Iss 4 (2019)
The β-3 sympathomimetic agonist BRL37344 restored nestin-positive cells within the stem cell niche, and thereby normalized blood counts and improved myelofibrosis in a mouse model of JAK2-V617F-positive myeloproliferative neoplasms. We therefore tes
Externí odkaz:
https://doaj.org/article/8479aa021716446aad1f99447b3fef97
Autor:
Bernhard Gerber, Martina Manzoni, Valeria Spina, Alessio Bruscaggin, Marta Lionetti, Sonia Fabris, Marzia Barbieri, Gabriella Ciceri, Alessandra Pompa, Gabriela Forestieri, Erika Lerch, Paolo Servida, Francesco Bertoni, Emanuele Zucca, Michele Ghielmini, Agostino Cortelezzi, Franco Cavalli, Georg Stussi, Luca Baldini, Davide Rossi, Antonino Neri
Publikováno v:
Haematologica, Vol 103, Iss 6 (2018)
Externí odkaz:
https://doaj.org/article/cac49ae32fee42aa814cbe7b70af622f
Autor:
Jakob R. Passweg, Helen Baldomero, Marc Ansari, Gabriela M. Baerlocher, Mario Bargetzi, Yves Chalandon, Michel A. Duchosal, Sabine Gerull, Tayfun Güngör, Jörg P. Halter, Dominik Heim, Urs Hess, Kurt Leibundgut, Stavroula Masouridi-Levrat, Antonia Müller, Gayathri Nair, Thomas Pabst, Christoph Renner, Adrian Schmidt, Georg Stussi, Grazia Nicoloso de Faveri, Urs Schanz, for the Swiss Blood Stem Cell Transplantation Group (SBST)
Publikováno v:
Swiss Medical Weekly, Vol 148, Iss 0910 (2018)
In 1997, the Swiss Blood Stem Cell Transplantation Group (SBST) initiated a mandatory national registry for all haematopoietic stem cell transplants (HCTs) in Switzerland. As of 2016, after 20 years, information was available for 7899 patients who ha
Externí odkaz:
https://doaj.org/article/c36c8bd0307b48e194437f606e771da4